PTM - dbPAF Gene Name UniProt ID Position Type Species Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 1007 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 1008 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 1010 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 1011 T Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 1029 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 1032 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 1034 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 1047 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 137 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 234 T Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 235 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 237 T Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 241 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 256 T Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 378 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 405 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 419 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 420 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 513 T Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 514 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 515 T Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 543 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 546 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 552 Y Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 557 Y Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 566 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 592 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 595 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 596 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 607 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 608 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 619 Y Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 637 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 638 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 641 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 643 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 647 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 650 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 656 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 659 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 661 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 719 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 721 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 764 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 766 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 792 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 794 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 797 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 805 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 812 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 819 T Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 822 T Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 916 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 937 T Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 972 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 976 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 993 S Mus musculus(Mouse) Sh3pxd2a; Fish; Sh3md1; Tks5 O89032 995 T Mus musculus(Mouse)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O89032 R786-m1 Methylation LRPTGQLrGGLKGSR O89032 R1001-m1 Methylation LTATDSLrGVRRNss O89032 S84-p Phosphorylation GKILFRRsHIRDVAV O89032 T234-p Phosphorylation RDDSDINtsKtGEVs O89032 S235-p Phosphorylation DDSDINtsKtGEVsK O89032 T237-p Phosphorylation SDINtsKtGEVsKRR O89032 S241-p Phosphorylation tsKtGEVsKRRKAHL O89032 T256-p Phosphorylation RRLDRRWtLGGMVNR O89032 S378-p Phosphorylation PITKKEIsLPILCNA O89032 S405-p Phosphorylation TSKLAQGsPAVARIA O89032 S419-p Phosphorylation APQRAQIssPNLRTR O89032 S420-p Phosphorylation PQRAQIssPNLRTRP O89032 T513-p Phosphorylation KPNLSRRtstLTRPK O89032 S514-p Phosphorylation PNLSRRtstLTRPKV O89032 T515-p Phosphorylation NLSRRtstLTRPKVP O89032 S543-p Phosphorylation NPVGACEsQGsPLKV O89032 S546-p Phosphorylation GACEsQGsPLKVKyE O89032 Y552-p Phosphorylation GsPLKVKyEEPEyDV O89032 Y557-p Phosphorylation VKyEEPEyDVPAFGF O89032 S566-p Phosphorylation VPAFGFDsEPEMNEE O89032 S592-p Phosphorylation PAQPRRIsPASsLQR O89032 S596-p Phosphorylation RRIsPASsLQRAHFK O89032 S607-p Phosphorylation AHFKVGEsSEDVALE O89032 Y619-p Phosphorylation ALEEETIyENEGFRP O89032 S641-p Phosphorylation ARGSSGDsDsPGSSS O89032 S643-p Phosphorylation GSSGDsDsPGSSSLS O89032 S656-p Phosphorylation LSLAVKNsPKSDsPK O89032 S661-p Phosphorylation KNsPKSDsPKSSSLL O89032 S719-p Phosphorylation NGDLKPRsAsDAGIR O89032 S721-p Phosphorylation DLKPRsAsDAGIRDT O89032 S764-p Phosphorylation PVLNRAEsQsQEKMD O89032 S766-p Phosphorylation LNRAEsQsQEKMDIS O89032 S794-p Phosphorylation GGLKGSRsEDSELPP O89032 S812-p Phosphorylation SEGSRRGsADIIPLt O89032 T819-p Phosphorylation sADIIPLtATtPPCV O89032 T822-p Phosphorylation IIPLtATtPPCVPKK O89032 S916-p Phosphorylation QNEGKSDsLEKIEKR O89032 T937-p Phosphorylation VNQSKRAtPPIPSKP O89032 S972-p Phosphorylation QVAVRPQsVFVsPPP O89032 S976-p Phosphorylation RPQsVFVsPPPKDNN O89032 S993-p Phosphorylation CALRRNEsLTATDSL O89032 S1007-p Phosphorylation LrGVRRNssFSTARS O89032 S1008-p Phosphorylation rGVRRNssFSTARSA O89032 S1029-p Phosphorylation RLAERAAsQGsEsPL O89032 S1032-p Phosphorylation ERAAsQGsEsPLLPT O89032 S1034-p Phosphorylation AAsQGsEsPLLPTQR O89032 S1047-p Phosphorylation QRKGIPVsPVRPKPI

PTM - dbPTM UniProt ID Position Code Type Resources References O89032 546 S Phosphorylation Swiss-Prot 1010711 17114649 O89032 566 S Phosphorylation Swiss-Prot 1010711 19367708 O89032 993 S Phosphorylation Swiss-Prot 1010711 19367708 O89032 546 S Phosphorylation PhosphoELM.10011 17114649 O89032 1007 S Phosphorylation Phosphositeplus.1010730 19367708;21183079 O89032 1008 S Phosphorylation Phosphositeplus.1010730 19367708;21183079 O89032 1029 S Phosphorylation Phosphositeplus.1010730 19367708;20415495;21183079 O89032 1032 S Phosphorylation Phosphositeplus.1010730 18779572 O89032 1034 S Phosphorylation Phosphositeplus.1010730 21183079 O89032 419 S Phosphorylation Phosphositeplus.1010730 21183079 O89032 420 S Phosphorylation Phosphositeplus.1010730 18779572;19367708;20139300;21183079 O89032 546 S Phosphorylation Phosphositeplus.1010730 17114649;19367708;20415495;21183079;21659604;21659605 O89032 566 S Phosphorylation Phosphositeplus.1010730 18515860;19367708 O89032 592 S Phosphorylation Phosphositeplus.1010730 18779572;19367708;20139300;20531401;21183079;21659604;21659605 O89032 596 S Phosphorylation Phosphositeplus.1010730 21183079 O89032 607 S Phosphorylation Phosphositeplus.1010730 21183079 O89032 643 S Phosphorylation Phosphositeplus.1010730 20415495;21183079 O89032 719 S Phosphorylation Phosphositeplus.1010730 19367708 O89032 764 S Phosphorylation Phosphositeplus.1010730 21183079 O89032 766 S Phosphorylation Phosphositeplus.1010730 21183079 O89032 797 S Phosphorylation Phosphositeplus.1010730 21183079 O89032 805 S Phosphorylation Phosphositeplus.1010730 21183079 O89032 812 S Phosphorylation Phosphositeplus.1010730 17242355;19367708;21183079;21659604;21659605 O89032 972 S Phosphorylation Phosphositeplus.1010730 19367708 O89032 993 S Phosphorylation Phosphositeplus.1010730 17242355;19367708;20415495;21183079;21659604 O89032 256 T Phosphorylation Phosphositeplus.1010730 19367708;21183079;21659605 O89032 819 T Phosphorylation Phosphositeplus.1010730 21183079;21659604;21659605 O89032 822 T Phosphorylation Phosphositeplus.1010730 21183079;21659604;21659605 O89032 995 T Phosphorylation Phosphositeplus.1010730 21183079 O89032 552 Y Phosphorylation Phosphositeplus.1010730 19596797 O89032 557 Y Phosphorylation Phosphositeplus.1010730 18515860;18563927;19596797 O89032 619 Y Phosphorylation Phosphositeplus.1010730 18515860;19596797 O89032 420 S Phosphorylation SysPTM 1.1 18779572 O89032 546 S Phosphorylation SysPTM 1.1 17114649 O89032 566 S Phosphorylation SysPTM 1.1 18515860 O89032 592 S Phosphorylation SysPTM 1.1 18779572 O89032 812 S Phosphorylation SysPTM 1.1 17242355 O89032 993 S Phosphorylation SysPTM 1.1 17242355 O89032 1032 S Phosphorylation SysPTM 1.1 18779572 O89032 557 Y Phosphorylation SysPTM 1.1 18515860;18563927 O89032 619 Y Phosphorylation SysPTM 1.1 18515860

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type O89032 546 S 17114649 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs O89032 256 Phosphothreonine 21183079 O89032 546 Phosphoserine 21183079 O89032 643 Phosphoserine 21183079 O89032 764 Phosphoserine 21183079 O89032 766 Phosphoserine 21183079 O89032 812 Phosphoserine 17242355;21183079 O89032 822 Phosphothreonine 21183079 O89032 993 Phosphoserine 21183079 O89032 1007 Phosphoserine 21183079 O89032 1008 Phosphoserine 21183079 O89032 1029 Phosphoserine 21183079

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type Sh3pxd2a IPI00280250 S 1007 RGVRRNpSSFSTAR phosphorylation Sh3pxd2a IPI00280250 S 1008 GVRRNSpSFSTARS phosphorylation Sh3pxd2a IPI00280250 S 1029 LAERAApSQGSESP phosphorylation Sh3pxd2a IPI00280250 S 1034 ASQGSEpSPLLPTQ phosphorylation Sh3pxd2a IPI00280250 S 1047 RKGIPVpSPVRPKP phosphorylation Sh3pxd2a IPI00280250 S 420 QRAQISpSPNLRTR phosphorylation Sh3pxd2a IPI00280250 S 546 ACESQGpSPLKVKY phosphorylation Sh3pxd2a IPI00280250 S 592 AQPRRIpSPASSLQ phosphorylation Sh3pxd2a IPI00280250 S 643 SSGDSDpSPGSSSL phosphorylation Sh3pxd2a IPI00280250 S 719 GDLKPRpSASDAGI phosphorylation Sh3pxd2a IPI00280250 S 812 EGSRRGpSADIIPL phosphorylation Sh3pxd2a IPI00280250 S 993 ALRRNEpSLTATDS phosphorylation