PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Rbbp4 Pgls 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ezh1 Rbbp4 20064376 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Runx1 Rbbp4 22325351 biogrid exp G G G G G G G G G G G G G G G G Rbbp4 Uncharacterized protein C17orf96 homolog 23180766 biogrid,dip exp G G G G G Gata1 Rbbp4 15920471 biogrid exp G G G G G G G Rbbp4 Kdm2b 17296600 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Aicda 21186367 innatedb,intact exp G H3f3a, H3f3b Rbbp4 20211137 intact exp P Tcf3 Rbbp4 22354994 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Sall4 20362541 biogrid,intact exp Otx2 Rbbp4 26426291 biogrid exp G Rbbp4 Esrrb 20362541 biogrid exp G G G L3mbtl2 Rbbp4 22770845 biogrid exp Tfcp2l1 Rbbp4 20362541 intact exp G G G G G G G G G G G G G G Rbbp4 Nanog 21589869 biogrid exp Mtf2 Rbbp4 20064376 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhae Rbbp4 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Eed 20064376 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Suv39h1 Rbbp4 11788710 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Ezh2 20064376,23624931,20123894 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G Zfpm1 Rbbp4 i2d exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G Sap30 Rbbp4 9702189 intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Rnf2 17296600 biogrid,intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Jarid2 20064376 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hdac1 Rbbp4 11302704 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hist1h3b, Hist1h3c, Hist1h3d, Hist1h3e, Hist1h3f, Hist2h3b, Hist2h3c1, Hist2h3c2 Rbbp4 20211137 intact exp, ortho P G G G G Rbbp4 Suz12 22438827 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hist1h3a, Hist1h3g, Hist1h3h, Hist1h3i Rbbp4 20211137 intact exp, ortho P Rbbp4 Mta2 15920471 biogrid,i2d exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sox2 Rbbp4 21532573 intact exp, ortho G G G G G G G G G G G Sp3 Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Loxl2 Rbbp4 ortho G G G G Rbbp4 Rpn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Gatad2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Hat1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Dyrk4 ortho Rbbp4 Gatad2a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tk1 Rbbp4 ortho G G G G G G G G G G G G G Nr2c2 Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 HMG box domain containing 4, Protein Hmgxb4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Hdac6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Npm1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lamp2 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Tssk3 ortho G Rbbp4 Cdc5l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Atg5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo2 Rbbp4 ortho P Jun Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Taf6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hdgf Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Brms1 ortho G G G G G G G G G G G G G G G G G Rbbp4 Chd4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lrrk2 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G Esr1 Rbbp4 ortho G G G G G Kmt2a Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Setd8 Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Hist2h2ac ortho P Rbbp4 Hcfc1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdkn1a Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hist1h4a, Hist1h4b, Hist1h4c, Hist1h4d, Hist1h4f, Hist1h4h, Hist1h4i, Hist1h4j, Hist1h4k, Hist1h4m, Hist2h4a, Hist4h4 Rbbp4 ortho P G G G G G G G G G G G G G G Cd81 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Eaf2 ortho G G G G G G Rbbp4 Usf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Arid4a Rbbp4 ortho Rbbp4 Mta3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdk2ap1 Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ikzf1 Rbbp4 ortho P G G G G G Rbbp4 Zeb2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mtpn Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sirt6 Rbbp4 ortho Ubc Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gabarapl2 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Ncor1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Hdac4 ortho Mybl2 Rbbp4 ortho G G G G G G G Rbbp4 Aebp2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Xrcc6 Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Lin9 ortho G G G G G Rbbp4 Ddx39b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Git2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Cdyl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 E2f1 ortho G G G G G Cep76 Rbbp4 ortho Nr2c1 Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Phf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Ppp1r8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmc4 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sp1 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Phf19 ortho G G G G G G G G G G G Hdac2 Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Chaf1b ortho G G G G G G G G G G G G G Rbbp4 Mbd2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Bcl11b ortho G G G G G G G G G G G G G Rbbp4 Cbx5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Rbl1 ortho G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Irak2 ortho Rbbp4 Smarca2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Hic1 ortho G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Zfpm2 ortho G G G G G G G G G G G G G Rbbp4 Smarca1 ortho G G G G G G G G G G G G G G G Chd5 Rbbp4 ortho P Rbbp4 Kdm5b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Chd3 Rbbp4 ortho P Cul4a Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Bap18 ortho P Ctnnb1 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Nr2e3 ortho G Rbbp4 Rassf9 ortho G Rbbp4 Park7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hipk4 Rbbp4 ortho Rbbp4 Spen ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Dhx30 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vhl Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Kdm1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Zfp219 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gata3 Rbbp4 ortho G G G G G Rbbp4 Eif1b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Baz1a Rbbp4 ortho Nkx3-2 Rbbp4 ortho Anxa7 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vcp Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Nasp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Smarcb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dnmt3b Rbbp4 ortho G G G G G G G G G G G Rbbp4 Smarca5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Gabarap ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Elavl1 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rb1 Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Fbxo6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Mcm7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Asf1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Cdk20 ortho G G G G G G G Rbbp4 Racgap1 ortho G G G G G G G G G G G G G G G G G G G G Rbbp4 Zgpat ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Ing1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Brca1 Rbbp4 ortho G G G G G G G G G G G G G Tp53 Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nap1l1 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tubgcp3 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cit Rbbp4 ortho G G G G G Ntrk1 Rbbp4 ortho Rbbp4 E2f5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Rpn2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Mbd3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Ing2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sin3a Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Mbd3l1 ortho G Srsf6 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Rbl2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Eif3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Mta1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fn1 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Dpy30 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cenpa Rbbp4 ortho G G G G G G G G G G G G G G G G G G G Creb1 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G Rbbp4 Lin37 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Fam64a ortho G G G Kif4 Rbbp4 ortho G G G G G G G G G G Rbbp4 Asf1b ortho G G G G G G G G G G G G G G G G Brms1l Rbbp4 ortho Rbbp4 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atp6v1a Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hdac3 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Notch1 Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Uncharacterized protein KIAA1143 homolog ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Isg15 ortho P Rbbp4 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Lin52 ortho Hmox2 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pdia3 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Znf827 Rbbp4 ortho Rbbp4 Gnl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Shb ortho P Rbbp4 Pold3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Csnk1a1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cul4b Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Chaf1a ortho Mcm3 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G Rbbp4 Psmd13 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Appl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Bptf Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Nop58 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crebbp Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cep250 Rbbp4 ortho Rbbp4 Nacc2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Csnk2a1 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Rassf10 ortho Rbbp4 Igsf8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Sirt7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Pan2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Gabarapl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Ppa1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Topors ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Mis18a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Mib1 ortho P G G G G G G G G G Rbp1 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Cul7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Smarca4 Rbbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lin54 Rbbp4 ortho Lmna Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Banf1 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Phf6 ortho Rplp0 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Hdac5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dnmt1 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Hjurp ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q60972 - 14645126 - X 2 Q60972 E9PVV2 affinity chromatography technology 22354994 physical association X 2 Q60972 G3X9W7 affinity chromatography technology 22325351 physical association X 2 Q60972 A2RS90 affinity chromatography technology 21589869 physical association X 2 Q60972 affinity chromatography technology 20123894 physical association X 2 Q60972 affinity chromatography technology 20362541 physical association X 2 Q60972 affinity chromatography technology 20362541 physical association X 2 Q60972 Q921E6 affinity chromatography technology 20064376 physical association X 2 Q60972 affinity chromatography technology 20064376 physical association X 2 Q60972 affinity chromatography technology 20064376 physical association X 2 Q60972 Q9R190 affinity chromatography technology 15920471 physical association X 2 Q60972 Q9CQJ4 affinity chromatography technology 17296600 physical association X 2 Q60972 Q6P1G2-4 affinity chromatography technology 17296600 physical association X 2 P59178 Q60972 affinity chromatography technology 22770845 physical association X 2 P59178 Q60972 affinity chromatography technology 22770845 physical association X 2 Q60972 Q16695 enzymatic study 22619169 direct interaction X 2 Q60972 Q80U70 affinity chromatography technology 22438827 physical association X 2 Q60972 O09106 affinity chromatography technology 11302704 physical association X 2 Q60972 Q7TNS8 affinity chromatography technology 23180766 physical association X 2 Q60972 Q62315 affinity chromatography technology 20064376 physical association X 2 Q60972 affinity chromatography technology 20064376 physical association X 2 Q60972 P17679 affinity chromatography technology 15920471 physical association X 2 Q60972 coimmunoprecipitation 15920471 association C 13 Q60972 anti tag coimmunoprecipitation 14612411 association C 7 Q60972 anti tag coimmunoprecipitation 10204490 association C 12 Q60972 anti tag coimmunoprecipitation 23180766 - C 28 Q60972 anti tag coimmunoprecipitation 23142980 - C 5 O43189 Q60972 anti tag coimmunoprecipitation 23142980 physical association X 2 Q60972 Q7TNS8 anti tag coimmunoprecipitation 23180766 physical association X 2 Q60972 cosedimentation 16615898 colocalization C 1216 Q60972 anti tag coimmunoprecipitation 20064376 association C 12 Q60972 pull down 23624931 association C 129 Q60972 pull down 21186367 association C 20 Q60972 anti tag coimmunoprecipitation 20064376 association C 12 Q60972 anti bait coimmunoprecipitation 21532573 association C 30 Q60972 pull down 11788710 association C 5 Q60972 pull down 20211137 physical association C 24 Q60972 anti tag coimmunoprecipitation 20064376 association C 5 Q60972 anti tag coimmunoprecipitation 20064376 association C 5 Q60972 anti tag coimmunoprecipitation 20064376 association C 8 Q60972 pull down 20211137 association C 24 Q60972 pull down 17296600 association C 52 Q60972 anti tag coimmunoprecipitation 20064376 association C 9 Q60972 anti tag coimmunoprecipitation 20064376 association C 10 Q60972 anti tag coimmunoprecipitation 21532573 association C 50 Q60972 pull down 20211137 physical association C 32 Q60972 anti tag coimmunoprecipitation 20362541 association C 42 Q60972 anti tag coimmunoprecipitation 20064376 association C 17 O88574 Q60972 coimmunoprecipitation 9702189 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Rbbp4 Mta2 MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0004(affinity chromatography technology)|MI:0027(cosedimentation)|MI:0027(cosedimentation) 15920471,16615898 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization) (intact)|(intact)|(intact)|(biogrid)|(intact)|(intact) UniProt_167137|UniProt_167121|UniProt_167133|BIOGRID_314936|UniProt_167125|UniProt_167129 neutral component|neutral component|neutral component|prey|neutral component|neutral component neutral component|neutral component|neutral component|bait|neutral component|neutral component Rbbp4 Eed MI:0027(cosedimentation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 16615898,20064376 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(biogrid) UniProt_167137|UniProt_170405|UniProt_170404|UniProt_170428|UniProt_170427|UniProt_170406|BIOGRID_314287 neutral component|prey|prey|prey|prey|prey|prey neutral component|null|null|prey|bait|null|bait Rbbp4 Esrrb MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 20362541 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_314122|UniProt_170698|UniProt_107199 prey|prey|prey bait|bait|bait Rbbp4 uniprotkb:(gene name) MI:0004(affinity chromatography technology) 23180766 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_328791 prey bait Rbbp4 Kdm2b MI:0004(affinity chromatography technology) 17296600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_315747 prey bait Hdac1 Rbbp4 MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0004(affinity chromatography technology)|MI:0027(cosedimentation) 11302704,16615898 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization) (intact)|(intact)|(intact)|(intact)|(biogrid)|(intact) UniProt_167137|UniProt_167117|UniProt_167133|UniProt_167125|BIOGRID_324265|UniProt_167129 neutral component|neutral component|neutral component|neutral component|bait|neutral component neutral component|neutral component|neutral component|neutral component|prey|neutral component L3mbtl2 Rbbp4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22770845 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_328078|BIOGRID_328042 bait|bait prey|prey Sap30 Rbbp4 MI:0019(coimmunoprecipitation) 9702189 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_176713 bait prey Mtf2 Rbbp4 MI:0004(affinity chromatography technology) 20064376 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_314334 bait prey Rbbp4 Jarid2 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 20064376 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_170409|BIOGRID_314318 prey|prey bait|bait Rbbp4 Sall4 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 20362541 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(biogrid) UniProt_107198|UniProt_170697|BIOGRID_313969 prey|prey|prey bait|bait|bait Gata1 Rbbp4 MI:0004(affinity chromatography technology) 15920471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_314928 bait prey Rbbp4 Ezh2 MI:0027(cosedimentation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 16615898,20064376,20123894 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) (intact)|(biogrid)|(biogrid)|(intact) UniProt_167137|BIOGRID_312484|BIOGRID_314305|UniProt_170408 neutral component|prey|prey|prey neutral component|bait|bait|bait Runx1 Rbbp4 MI:0004(affinity chromatography technology) 22325351 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_320740 bait prey Rbbp4 Rnf2 MI:0027(cosedimentation)|MI:0004(affinity chromatography technology)|MI:0027(cosedimentation)|MI:0096(pull down)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation) 16615898,17296600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0914(association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization) (intact)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_167137|BIOGRID_315701|UniProt_167121|UniProt_166511|UniProt_167117|UniProt_167133|UniProt_167125 neutral component|prey|neutral component|prey|neutral component|neutral component|neutral component neutral component|bait|neutral component|prey|neutral component|neutral component|neutral component Rbbp4 Nanog MI:0428(imaging technique) 21589869 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_321501 prey bait Ezh1 Rbbp4 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20064376 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_314298|UniProt_170407 bait|bait prey|prey Tcf3 Rbbp4 MI:0004(affinity chromatography technology) 22354994 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_320650 bait prey

PPI - HINT Gene A Gene B PMID Method Quality ZFPM1 RBBP4 15920470,15920470,15920470 0019,0004,0071 LC SAP30 RBBP4 9702189 0019 LC YWHAE RBBP4 16615898 0027 LC RBBP4 PGLS 16615898 0027 LC HDAC1 RBBP4 11302704 0004 LC ZFPM1 RBBP4 15920470,15920470,15920470 0019,0004,0071 LC SUV39H1 RBBP4 11788710 0096 LC TCF3 RBBP4 22354994 0004 LC GATA1 RBBP4 15920471 0004 LC SOX2 RBBP4 21532573,21532573 0007,0006 LC L3MBTL2 RBBP4 22770845 0004 LC HIST1H3A|HIST1H3G|HIST1H3H|HIST1H3I RBBP4 20211137 0096 LC EZH1 RBBP4 20064376,20064376 0007,0004 LC OTX2 RBBP4 26426291 0004 LC HIST1H3B|HIST1H3C|HIST1H3D|HIST1H3E|HIST1H3F|HIST2H3B|HIST2H3C1|HIST2H3C2 RBBP4 20211137 0096 LC H3F3A|H3F3B RBBP4 20211137 0096 LC MTF2 RBBP4 20064376 0004 LC RUNX1 RBBP4 22325351 0004 LC TFCP2L1 RBBP4 20362541 0007 LC RBBP4 EZH2 20123894,20064376,20064376,23624931 0004,0004,0007,0096 LC RBBP4 ESRRB 20362541 0004 LC RBBP4 JARID2 20064376,20064376 0007,0004 LC RBBP4 KDM2B 17296600 0004 LC RBBP4 Q7TNS8 23180766,23180766 0004,0007 LC RBBP4 SUZ12 22438827 0004 LC RBBP4 NANOG 21589869 0004 LC RBBP4 SALL4 20362541,20362541 0004,0007 LC RBBP4 EED 20064376,20064376 0007,0004 LC RBBP4 RNF2 17296600,17296600 0096,0004 LC RBBP4 CHAF1A 26365490 0004 LC RBBP4 MTA2 15920471 0004 LC RBBP4 AICDA 21186367 0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q60972 P59178 RBBP4 L3MBTL2 0.21 22770845 Q60972 P15806 RBBP4 TCF3 0.126 22354994 Q60972 O88574 RBBP4 SAP30 0.21 9702189 Q60972 P70351 RBBP4 EZH1 0.332 20064376 Q61188 Q60972 EZH2 RBBP4 0.472 20064376,20123894 Q62315 Q60972 JARID2 RBBP4 0.332 20064376 Q61539 Q60972 ESRRB RBBP4 0.126 20362541 Q60972 P62259 RBBP4 YWHAE 0.081 16615898 Q60972 O54864 RBBP4 SUV39H1 0.21 11788710 Q7TNS8 Q60972 Q7TNS8 RBBP4 0.21 23180766 Q6AXH7 Q60972 EZH2 RBBP4 0.126 23624931 Q80U70 Q60972 SUZ12 RBBP4 0.21 22438827 Q80Z64 Q60972 NANOG RBBP4 0.126 21589869 Q6P1G2 Q60972 KDM2B RBBP4 0.126 17296600 Q9CQJ4 Q60972 RNF2 RBBP4 0.236 17296600 Q60I23 Q60972 SOX2 RBBP4 0.236 21532573 Q8BX22 Q60972 SALL4 RBBP4 0.236 20362541 Q921E6 Q60972 EED RBBP4 0.332 20064376 Q9CQ60 Q60972 PGLS RBBP4 0.081 16615898 Q9QWF0 Q60972 CHAF1A RBBP4 0.126 26365490 Q9R190 Q60972 MTA2 RBBP4 0.21 15920471 Q60972 P17679 RBBP4 GATA1 0.21 15920471 Q60972 P84228 RBBP4 HIST2H3C2 0.236 20211137 Q60972 P84244 RBBP4 H3F3B 0.126 20211137 Q60972 Q02395 RBBP4 MTF2 0.126 20064376 Q60972 P68433 RBBP4 HIST1H3I 0.126 20211137 Q60972 O09106 RBBP4 HDAC1 0.21 11302704 Q60972 Q3UNW5 RBBP4 TFCP2L1 0.126 20362541