PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Top2a MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 23086144 biogrid exp G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Rnf112 24359566 biogrid exp G G G G G G Lmnb1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 23086144 biogrid exp G G G G G G G G G G G G G G G G G G Hp1bp3 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 23086144 biogrid exp G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Keap1 23086144 biogrid exp G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Cul3 23086144 biogrid exp G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Nup98 23086144 biogrid exp G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Nup88 23086144 biogrid exp G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Zbtb33 i2d exp MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Skor1 15528197 biogrid exp MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Nup214 23086144 biogrid exp Dnmt1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 23086144 biogrid exp G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Satb1 23086144 biogrid exp G G G G G G G G G G G G G G G G Bach2 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 16331266 biogrid exp G G G G G G G G G G G G Hist1h4a, Hist1h4b, Hist1h4c, Hist1h4d, Hist1h4f, Hist1h4h, Hist1h4i, Hist1h4j, Hist1h4k, Hist1h4m, Hist2h4a, Hist4h4 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 23086144 biogrid exp G G G G G G G Protein Nup153 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 23086144 biogrid exp G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Pml 19523849 innatedb,biogrid exp, ortho G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 16331266,23086144 biogrid exp, ortho G G G G G G G G G G G G G G G G G G Hdac1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 19523849,23086144 innatedb,biogrid exp, ortho G G G G G G G G G G G G G G G G G G Grb7 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Glutathione S-transferase mu 4, Glutathione S-transferase, mu 4, Glutathione transferase GSTM7-7, Protein Gstm4 ortho G G G G G G G G G G G G G G G G G G Hdx MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho Tp53 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Hdac6 ortho G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Lamtor5 ortho G G G G G G G G G G G G G G G G G G Ube2i MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Agtr2 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Hdac4 ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Zbtb32 ortho G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Hdac9 ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Pgam5 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Kiaa1549 ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 UPF0183 protein C16orf70 homolog ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Fam101b ortho G G G G G G G G G G G G G G G G G Cdk1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G Sumo1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Spry2 ortho G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Znf281 ortho G G G G G G G G G G G G G G G G G G Hdac2 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Sp1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Ep300 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Vta1 ortho G G G G G G G G G G G G G G G G G G Bmi1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Ar MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G Gata2 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Coq6 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Psmd11 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Pnrc2 ortho G G G G G G G G G G G G G G G G G G Anxa7 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Cdkn1a MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G Lsm2 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Ncor1 ortho G G G G G G G G G G G G G G G G G G Terf1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Gcsh ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Sin3a ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Trim27 ortho G G G G G G G G G G G G G G G G G G Bcl6 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Ccdc109b ortho G G G G G G G G G G G Rxra MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Txnip ortho G G G G G G G G G G G G G G G G G G Cidea MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Qtrt1 ortho G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Cep72 ortho Protein Magea4 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Ncor2 ortho G G G G G G G G G G G G G G G G G G Erg MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Pafah1b3 ortho G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Ccdc85b ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Tab2 ortho G G G G G G G G G G G G G G G G G G Dnm2 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Anapc5 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Smad3 ortho G G G G G G G G G Dnaaf5 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G Lyar MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Plscr1 ortho G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Lmtk3 ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Map3k3 ortho G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Mbd3 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Mta2 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Ldoc1 ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Sept10 ortho G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Mtdh ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Spop ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Atp6ap2 ortho G G G G G G G G G G G G G G G G G G Fhl2 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Epn1 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Sin3b ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Atp7b ortho G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Tollip ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Rab27a ortho G G G G G Gnao1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Ccdc130 ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Trim54 ortho G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Hdac5 ortho G G G G G G G G G G G G G G G G G G Il6 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Cbx5 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Eif2s2 ortho G G G G G G G G G G G G G G G G G G Eef1a1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Parp1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Krt40 ortho Rara MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Gne ortho G G G G G G G G G G G G G G G G G G Htt MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Fcho1 ortho G G G G G G G G G G Nr3c1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Vdr MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Cep70 ortho G G G G G G G G G G G G G G G Casp3 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Enox1 ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Adamts4 ortho G G G G G G Hdac3 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Cdk4 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Timp1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Golga2 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Sh2d4a ortho MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Hdac7 ortho G G G G G G G G G G G G G G G G G G Rb1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Dlst ortho G G G G G G G G G G G G G G G G G G Cfh MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G Traf2 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G Fshr MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G Gata1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Runx1t1 ortho G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Thnsl2 ortho G G G G G G G G G G G G G Esr1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G Hbegf MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Psmd2 ortho G G G G G G G G G G G G G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Znf24 ortho G G G G G G G G G G G G G G G G G G Tk1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 Wdr33 ortho G G G G G G G G G G G G G G G G G G Dpm1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Cebpa MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G Cd81 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Tnk2 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Prkce MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Lmnb1 Zbtb16 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_323410|BIOGRID_323420 prey|prey bait|bait Zbtb16 Skor1 MI:0004(affinity chromatography technology) 15528197 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_328605 prey bait Zbtb16 Cul3 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_323422|BIOGRID_323403|BIOGRID_323416|BIOGRID_323398 prey|bait|bait|prey bait|prey|prey|bait Top2a Zbtb16 MI:0004(affinity chromatography technology) 23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_323413 prey bait Zbtb16 Pml MI:0004(affinity chromatography technology) 19523849 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_328930 bait prey Zbtb16 Nup88 MI:0004(affinity chromatography technology) 23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_323406 bait prey Hp1bp3 Zbtb16 MI:0004(affinity chromatography technology) 23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_323412 prey bait Hdac1 Zbtb16 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19523849,23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_328931|BIOGRID_323418|BIOGRID_323414 prey|prey|prey bait|bait|bait Zbtb16 Nup153 MI:0004(affinity chromatography technology) 23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_323408 bait prey Zbtb16 Nup98 MI:0004(affinity chromatography technology) 23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_323404 bait prey Zbtb16 Nup214 MI:0004(affinity chromatography technology) 23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_323409 bait prey Dnmt1 Zbtb16 MI:0004(affinity chromatography technology) 23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_323411 prey bait Zbtb16 Satb1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_323419|BIOGRID_323407 bait|bait prey|prey Hist1h4a; Zbtb16 MI:0004(affinity chromatography technology) 23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_323415 prey bait Zbtb16 Keap1 MI:0004(affinity chromatography technology) 23086144 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_323405 bait prey

PPI - HINT Gene A Gene B PMID Method Quality BACH2 ZBTB16 16331266 0018 LC ZBTB16 ZBTB16 16331266 0018 LC ZBTB16 RNF112 24359566 0018 LC HDAC1 ZBTB16 19523849,23086144 0004,0004 LC DNMT1 ZBTB16 23086144 0004 LC LMNB1 ZBTB16 23086144 0004 LC HIST1H4A|HIST1H4B|HIST1H4C|HIST1H4D|HIST1H4F|HIST1H4H|HIST1H4I|HIST1H4J|HIST1H4K|HIST1H4M|HIST2H4A|HIST4H4 ZBTB16 23086144 0004 LC TOP2A ZBTB16 23086144 0004 LC HP1BP3 ZBTB16 23086144 0004 LC ZBTB16 ZBTB16 23086144 0004 LC ZBTB16 SATB1 23086144 0004 LC ZBTB16 PML 19523849 0004 LC ZBTB16 NUP98 23086144 0004 LC ZBTB16 NUP214 23086144 0004 LC ZBTB16 NUP153 23086144 0004 LC ZBTB16 SKOR1 15528197 0004 LC ZBTB16 NUP88 23086144 0004 LC ZBTB16 CUL3 23086144 0004 LC ZBTB16 KEAP1 23086144 0004 LC