PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ywhae Nup62 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NXF2 Nup62 15820316 biogrid exp G G Nutf2 Nup62 10543952 biogrid exp P Nup62 Nxt1 11579093 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Nxf1 11579093,15820316 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Npm1 Nup62 18809582 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Traf3 Nup62 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Cul3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Nup54 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Smarce1 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Snapc5 ortho G Oip5 Nup62 ortho Fabp3 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G Traf2 Nup62 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Txlna ortho P Lmo2 Nup62 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kifc3 Nup62 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Kansl1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Fubp3 Nup62 ortho P Nup62 Krt20 ortho P G G G G G Nup62 Nup85 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Bfsp1 Nup62 ortho P G G Lrrk2 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G Abi2 Nup62 ortho Eef2 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Nup35 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspa5 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Nup93 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Atxn7 ortho G G G G G G G G G G G G Arfgef1 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Ikbip ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Hspb11 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mcm3 Nup62 ortho GP G G G G G G G G G G G G G G G G G G Nup62 Phf21a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ctnnb1 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Traf5 Nup62 ortho G G G G G G G G G G G G G G G G G Hsf2 Nup62 ortho Nup62 Chm ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kpna2 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Cchcr1 ortho Abl1 Nup62 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Ssc5d ortho Protein Klhl32 Nup62 ortho Nup62 Iscu ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Cep57l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G3bp1 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dtnb Nup62 ortho P G G G G G G G G G G G G G G G G G G G G G Irak1 Nup62 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Cul5 ortho P Kpnb1 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cep250 Nup62 ortho Nup62 Nup107 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Bloc1s6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Gopc ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Clic1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Ipo5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ccdc153 Nup62 ortho Nup62 Gtf2e2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Cenpu ortho Nup62 Tnpo3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Nupl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Ik ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Traf6 Nup62 ortho G G G G G G G G G G G G G G G G G G G G Ddx19a Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Ahctf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Eif4a3 ortho P Sp1 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Dtna ortho G G G G G G G G G G G G G G G G G Heatr5a Nup62 ortho P Adam15 Nup62 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Stau2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Ccdc146 Nup62 ortho Nup62 Ccdc53 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 L7rn6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddx3x Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kpna1 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G3bp2 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Gorasp2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Acox1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ift20 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Nup214 ortho P Irf3 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Nup88 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Rae1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Haus1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Xpo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Myd88 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Thap1 ortho Vcp Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Pin1 ortho P Nup62 Nup98 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ncl Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Xpo6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Ccdc150 ortho Nup62 UPF0500 protein C1orf216 homolog ortho Nup62 Mogs ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Agr3 ortho G G Pbx2 Nup62 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Ccdc121 Nup62 ortho Nup62 Ogt ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Pck1 ortho GP G G G G G G G G G G G G G G G Protein Nup153 Nup62 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q63850 Q99JX7 - 11579093 - X 2 P61971 Q63850 unspecified method 10543952 direct interaction X 2 Q63850 affinity chromatography technology 15820316 physical association X 2 Q63850 affinity chromatography technology 18809582 physical association X 2 Q63850 Q99JX7 affinity chromatography technology 15820316 physical association X 2 Q63850 Q99JX7 affinity chromatography technology 11579093 physical association X 2 Q63850 Q99JX7 pull down 11579093 direct interaction X 2 Q9QZV9 Q63850 affinity chromatography technology 11579093 physical association X 2 P61972 Q63850 unspecified method 10543952 direct interaction X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Nup62 Nxf1 MI:0027(cosedimentation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation) 11579093,15820316,16615898 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization) (intact)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_167137|BIOGRID_325348|BIOGRID_325346|BIOGRID_323995|UniProt_167121|UniProt_167117|UniProt_167133|UniProt_167125|UniProt_167129 neutral component|bait|bait|prey|neutral component|neutral component|neutral component|neutral component|neutral component neutral component|prey|prey|bait|neutral component|neutral component|neutral component|neutral component|neutral component Nup62 Nxf2 MI:0004(affinity chromatography technology) 15820316 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_323996 prey bait Nutf2 Nup62 MI:0114(x-ray crystallography) 10543952 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_331391 bait prey Npm1 Nup62 MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0004(affinity chromatography technology)|MI:0027(cosedimentation) 16615898,18809582 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization) (intact)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(intact) UniProt_167137|UniProt_167121|UniProt_167117|UniProt_167133|UniProt_167125|BIOGRID_323888|UniProt_167129 neutral component|neutral component|neutral component|neutral component|neutral component|bait|neutral component neutral component|neutral component|neutral component|neutral component|neutral component|prey|neutral component

PPI - HINT Gene A Gene B PMID Method Quality YWHAE NUP62 16615898 0027 LC NR3C1 NUP62 19581287,19581287 0096,0004 LC HSP90AA1 NUP62 19581287 0004 LC NPM1 NUP62 18809582 0004 LC NUP62 NXF1 11579093,15820316,11579093 0004,0004,0096 LC NUP62 NXF2 15820316 0004 LC NUP62 NXT1 11579093 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q63850 P61971 NUP62 NUTF2 0.309 10543952 Q63850 P61972 NUP62 NUTF2 0.309 10543952 Q63850 Q61937 NUP62 NPM1 0.21 18809582 Q63850 P62259 NUP62 YWHAE 0.081 16615898 Q63850 P07901 NUP62 HSP90AA1 0.21 19581287 Q9QZV9 Q63850 NXT1 NUP62 0.21 11579093 Q99JX7 Q63850 NXF1 NUP62 0.569 15820316,11579093