PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Protein Cbl Flt1 15001553 biogrid exp Protein Cbl Shc1 9918770 biogrid exp, ortho Protein Cbl Ubc 20029031 biogrid exp, ortho Protein Cbl Irs1 19546233 biogrid exp, ortho Protein Cbl Map3k11 19546888 biogrid exp, ortho Protein Cbl Ret 16525057 biogrid exp, ortho Protein Cbl Crk 9348226,11146548 biogrid exp, ortho Protein Cbl Met 20029031,8550620 biogrid exp, ortho Protein Cbl Lyn 14531861,8627181 biogrid exp, ortho Protein Cbl Pik3r1 8550620 biogrid exp, ortho Protein Cbl Grb2 9918770 biogrid exp, ortho Protein Cbl Protein Spry2, Sprouty homolog 2 (Drosophila) 20029031 biogrid exp, ortho Protein Cbl Hspa1l ortho Protein Cbl Nedd4 ortho Protein Cbl Tubb4b ortho Protein Cbl Sh3kbp1 ortho Protein Cbl Hspa9 ortho Protein Cbl Ctnnb1 ortho Protein Cbl Kdr ortho Protein Cbl Protein Sorbs3, Sorbin and SH3 domain containing 3, Sorbin and SH3 domain containing 3, isoform CRA_b ortho Protein Cbl Ptk2b ortho Protein Cbl Inpp5d ortho Protein Cbl Protein Cbl ortho Protein Cbl Pop1_predicted ortho Protein Cbl Dlg1 ortho Protein Cbl Frs2_predicted ortho Protein Cbl Eef1a1 ortho Protein Cbl Myo1e ortho Ube2d1 Protein Cbl ortho Protein Cbl Pxn ortho Protein Cbl Stat5a ortho Ssfa2_predicted Protein Cbl ortho Protein Cbl Trpv1 ortho Protein Cbl Vcam1 ortho Protein Cbl Eps8 ortho Protein Cbl Csk ortho Protein Cbl Iqgap1_predicted ortho Protein Cbl Pik3r3 ortho Protein Cbl Actb ortho Protein Cbl SLP76 ortho Protein Cbl Coronin ortho Protein Cbl Krt14 ortho Protein Cbl Cct8_predicted ortho Glucosylceramidase Protein Cbl ortho Protein Cbl Fnbp1 ortho Traf4_predicted Protein Cbl ortho Protein Cbl Shkbp1 ortho Protein Cbl Spred2 ortho Protein Cbl Irf1 ortho Protein Cbl Protein Cd19 ortho Protein Cbl Ywhag ortho Protein Cbl Ywhae ortho Nphp1_predicted Protein Cbl ortho Protein Cbl Il7r_predicted ortho Protein Cbl Bcar1 ortho Protein Cbl Tcn2 ortho Tyrosine-protein kinase Protein Cbl ortho Protein Cbl Protein Gapvd1 ortho Protein Cbl Ptk2 ortho Protein Cbl Blnk ortho Protein Cbl Vim ortho Protein Cbl Cd2ap ortho Protein Cbl Sptan1 ortho Protein Cbl Spta1 ortho Protein Cbl Smad3 ortho Protein Cbl Actg2 ortho Protein Cbl Acta1 ortho Fcgr1 Protein Cbl ortho Protein Cbl Prkcq ortho Protein Cbl Dbnl ortho Protein Cbl Tns4 ortho RGD1562071_predicted Protein Cbl ortho Protein Cbl Flot1 ortho Protein Mzf1, RCG27468, isoform CRA_c Protein Cbl ortho Protein Cbl CD40 molecule, TNF receptor superfamily member 5, Protein Cd40, Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a ortho Protein Cbl Myh10 ortho Protein Cbl Cdkl2 ortho Protein Cbl Protein Serpina5, Serine (Or cysteine) peptidase inhibitor, clade A, member 5 ortho Protein Cbl Ywhah ortho Ube2g2_predicted Protein Cbl ortho Protein Spry4, RCG49355 Protein Cbl ortho Protein Cbl Cftr ortho Protein Cbl Cblb ortho Protein Trim8 Protein Cbl ortho Protein Cbl Stap2 ortho Protein Cbl Yes1 ortho Protein Cbl Hspa5 ortho Protein Cbl Sts ortho Protein Cbl Ube2d2 ortho Protein Cbl PTEN/MMAC1 ortho Protein Cbl Lat ortho Protein Cbl Lat2 ortho Protein Cbl MGC94010 ortho Protein Cbl Src ortho Protein Cbl Arhgef7 ortho Protein Pik3cg Protein Cbl ortho Protein Cbl Map1lc3b ortho Protein Cbl Grap2 ortho RGD1563421_predicted Protein Cbl ortho Protein Cbl Ephb1 ortho Protein Cbl Sptbn1 ortho Protein Cbl Krt5 ortho Protein Cbl ICSBP ortho Protein Cbl Mapk8 ortho Protein Cbl Was_predicted ortho Protein Cbl Ywhab ortho Protein Cbl Ube2g1 ortho Protein Cbl Itsn1 ortho Protein Cbl Stat5b ortho Protein Cbl Sorbs2 ortho Bag1 Protein Cbl ortho Protein Cbl Krt1 ortho Protein Krt84, Type II keratin Kb24 Protein Cbl ortho Protein Cbl Scn5a ortho Protein Cbl Notch1 ortho Protein Cbl Gif ortho Protein Cbl Abi1 ortho Ube2m_predicted Protein Cbl ortho Protein Cbl Sh2b2 ortho Protein Cbl LOC683720 ortho Protein Cbl Krt18 ortho Protein Cbl Psmc1 ortho Protein Cbl Krt17 ortho Protein Cbl Asap1 ortho Usp21 Protein Cbl ortho Nck1 Protein Cbl ortho Protein Cbl Protein Ubash3b ortho Protein Cbl Inppl1 ortho Protein Cbl Pik3r2 ortho Protein Cbl Pdgfra ortho Protein Cbl Sirt2 ortho Dok3 Protein Cbl ortho Protein Cbl Lck ortho Protein Cbl Khdrbs1 ortho Protein Cbl Fyn ortho Protein Cbl Itch ortho Protein Cbl Fgr ortho Protein Cbl Csf1 ortho Protein Cbl Sh3gl2 ortho Protein Cbl Tubb5 ortho Protein Cbl Protein Sh3bp2 ortho Protein Cbl Erbb4 ortho Siglec10_predicted Protein Cbl ortho Protein Cbl Ostf1 ortho Eif5b Protein Cbl ortho Protein Cbl Mapk7 ortho Capza1 Protein Cbl ortho Protein Cbl Plcg1 ortho Protein Cbl Tgfbr2 ortho Protein Cbl Cd38 ortho Protein Cbl Syk ortho Protein Cbl Epor ortho Protein Cbl Xpo1 ortho Protein Cbl Prpsap2 ortho Protein Cbl Pik3cb ortho Protein Cbl Insr ortho Protein Cbl Ywhaz ortho Protein Cbl Cubn ortho Traf6 Protein Cbl ortho Protein Cbl Cd3z ortho Protein Cbl Hck ortho Protein Cbl Ptprc ortho Protein Cbl Vav1 ortho Protein Cbl Ptprs ortho Protein Cbl Actn1 ortho Protein Cbl Ptpn11 ortho Protein Cbl Sh3gl3 ortho Protein Cbl Ube2d3 ortho Protein Cbl Hspa4 ortho Protein Cbl Fibroblast growth factor receptor ortho Protein Cbl Nck2_predicted ortho Protein Cbl Ywhaq ortho Protein Cbl Protein Synm, RCG24674, isoform CRA_b ortho Protein Cbl Ntrk1 ortho Protein Cbl Capn1 ortho Protein Cbl Trim21_predicted ortho Protein Cbl F2rl1 ortho Protein Cbl Tuba1a ortho Protein Cbl Ephb6 ortho Protein Cbl Psmc5 ortho Protein Cbl Sla ortho Protein Cbl Tnfrsf1a ortho Protein Cbl Protein Sos1, Son of sevenless homolog 1 (Drosophila) ortho Protein Cbl Xrcc5 ortho Protein Cbl Sgta ortho Protein Cbl Snag1_predicted ortho Protein Cbl Ptpn6 ortho Protein Cbl Gapdh ortho Protein Cbl Stat3 ortho Protein Cbl Hras ortho Protein Cbl Frs3 ortho Protein Cbl Abl2_mapped ortho Protein Cbl Myo1c ortho Protein Cbl Htr2a ortho Protein Cbl Myh9 ortho Protein Cbl Igf1r ortho Protein Cbl Pdgfrb ortho Protein Cbl Protein Vav2 ortho Protein Cbl Notch3 ortho Protein Cbl Protein Sfn, RCG31390 ortho Protein Cbl Acaca ortho Protein Cbl Smad7 ortho Protein Cbl Hspa8 ortho Protein Cbl Lox ortho

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Lyn Cbl MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 14531861,8627181 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_334682|BIOGRID_335015|BIOGRID_334681 bait|prey|bait prey|bait|prey Flt1 Cbl MI:0004(affinity chromatography technology) 15001553 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_334669 prey bait Shc1 Cbl MI:0004(affinity chromatography technology) 9918770 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_335964 prey bait Irs1 Cbl MI:0004(affinity chromatography technology) 19546233 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_333972 prey bait Grb2 Cbl MI:0004(affinity chromatography technology) 9918770 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_335963 prey bait Pik3r1 Cbl MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 8550620 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_335017|BIOGRID_335016 bait|prey prey|bait Cbl Ret MI:0004(affinity chromatography technology) 16525057 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_333906 bait prey Crk Cbl MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 11146548,9348226 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_335466|BIOGRID_337653 bait|bait prey|prey Spry2 Cbl MI:0004(affinity chromatography technology) 20029031 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_333967 prey bait Map3k11 Cbl MI:0004(affinity chromatography technology) 19546888 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_335755 prey bait

PPI - HINT Gene A Gene B PMID Method Quality CBL RET 16525057 0004 LC CBL IRS1 19546233 0004 LC CBL FLT1 15001553 0004 LC CBL GRB2 9918770 0004 LC CBL LYN 14531861,14531861,8627181 0096,0004,0004 LC CBL SPRY2 20029031 0004 LC CBL SHC1 9918770 0004 LC CBL UBC 20029031 0004 LC CBL CRK 11146548,9348226 0004,0004 LC CBL PIK3R1 8550620 0004 LC CBL MAP3K11 19546888 0004 LC CBL EGFR 8550620,20029031 0004,0004 LC