DNA & RNA Element - microRNA Mirbase Acc miRNA Name Gene ID Gene Symbol miRNA Alignment Alignment Gene Alignment miRNA Start miRNA End Gene Start Gene End Genome Coordinates Conservation Align Score Seed Cat Energy mirSVR Score MIMAT0000577 rno-miR-337 297592 Spsb2 uuUCCGUAGUAUAU----CCUCGACUu || || | || | |||||||| cuAGACAACUUAAAAGCUGGAGCUGAg 2 22 62 88 [rn4:4:160933196-160933222:+] 0.5125 152 7 -15.85 -0.1190 MIMAT0004646 rno-miR-338* 297592 Spsb2 gugagucgUGGUC-CUAUAACAa |: || ||||||| aaaaaaaaAUGAGAUAUAUUGUc 2 15 189 211 [rn4:4:160933323-160933345:+] 0.5178 141 7 -5.94 -1.2162 MIMAT0005336 rno-miR-760-5p 297592 Spsb2 gcccgaGACCACCGGACUCCCc |||| | ||||||| uaaaagCUGGAG--CUGAGGGa 2 17 72 91 [rn4:4:160933206-160933225:+] 0.5125 149 7 -19.95 -0.2543 MIMAT0012835 rno-miR-615 297592 Spsb2 cuaggcucguggccCCUGGGGg ||||||| gagggaaggaggcuGGACCCCu 2 9 86 107 [rn4:4:160933220-160933241:+] 0.5125 140 7 -21.19 -0.3028 MIMAT0012837 rno-miR-632 297592 Spsb2 aggccGUCCUUUG-UCUGUg |||| ||| ||||| uuucaCAGG-AACAAGACAu 2 15 119 137 [rn4:4:160933253-160933271:+] 0.5178 120 0 -17.10 -0.6924 MIMAT0000782 rno-miR-10a-5p 297592 Spsb2 guguuuaagccuagaUGUCCCAu ||||||| ------cccuguggcACAGGGUg 2 9 1 17 [rn4:4:160933135-160933151:+] 0.5783 140 7 -16.10 -0.1588 MIMAT0000791 rno-miR-22 297592 Spsb2 ugucaagaaguugACCGUCGAa |||||||| auacuauaggcugUGGCAGCUu 2 10 145 166 [rn4:4:160933279-160933300:+] 0.5178 145 7 -17.36 -0.7804 MIMAT0000886 rno-miR-216a 297592 Spsb2 agugucaacggucgACUCUAau |||||| aaguaaaaaaaaaaUGAGAUau 3 9 184 205 [rn4:4:160933318-160933339:+] 0.5178 120 0 -6.10 -0.3329 MIMAT0000903 rno-miR-320 297592 Spsb2 agcgggagaguuggGUCGAAAa ||||||| acuauaggcuguggCAGCUUUg 2 9 147 168 [rn4:4:160933281-160933302:+] 0.5178 140 7 -9.98 -0.2068 MIMAT0003201 rno-miR-382 297592 Spsb2 gcuuaGGUGGUGCUUGUUGAAg |:: | : :||||||| cacugCUGGCCUAGACAACUUa 2 18 52 73 [rn4:4:160933186-160933207:+] 0.5125 145 7 -11.72 -0.3588

DNA & RNA Element - TRANSFAC Accession AS Description Species Entrez Pubmed Binding Info G094277 Spsb2 Rattus norvegicus 297592

DNA & RNA Element - miRNAMap Gene Name Mature miRNA Target Start Target End miRNA 3-5 Alignment Target 5-3 Spsb2; Ssb2 rno-miR-103 1 26 AGUAUCGGGACA---UGU----UACGA-CGA |||||| ||| :|||| || ------CCCUGUGGCACAGGGUGUGCUGGCA Spsb2; Ssb2 rno-miR-107 1 26 ACUAUCGGGACA---UGU----UACGA-CGA |||||| ||| :|||| || ------CCCUGUGGCACAGGGUGUGCUGGCA Spsb2; Ssb2 rno-miR-10a 5 19 GUGUUUAAGCCUAGAUGUCCCAU- :|| |||||||: -------GUGGC---ACAGGGUGU Spsb2; Ssb2 rno-miR-133a 75 106 UGUCGACCA--ACUUCC---------CCUGGUU |||||| |||:|| ||||| -AAGCUGGAGCUGAGGGAAGGAGGCUGGACCC- Spsb2; Ssb2 rno-miR-133b 75 106 AUCGACCA--ACUUCC---------CCUGGUU |||||| |||:|| ||||| AAGCUGGAGCUGAGGGAAGGAGGCUGGACCC- Spsb2; Ssb2 rno-miR-136 27 50 AGGUAGUAGUUUUGUUUACCUCA |:| |:| :::|||::||||| CCUACCGUGGGGACAGGUGGAGA Spsb2; Ssb2 rno-miR-142-3p 30 59 AGGUAU-----UUCAUC-CUUUGUGAUGU ||:|: |:||:| ||::||||:| ACCGUGGGGACAGGUGGAGAGGCACUGCU Spsb2; Ssb2 rno-miR-145 79 105 UUCCCUAAGGACCCUUU---UGACCUG- ||| : |||||: :|||||| --UGGAGCUGAGGGAAGGAGGCUGGACC Spsb2; Ssb2 rno-miR-152 39 58 GGGUUCAAGACAGUACGUGACU ||:|| | | |||||| -ACAGGUG--GAGAGGCACUGC Spsb2; Ssb2 rno-miR-15b 3 26 -ACAUU-UGGUACUACACGA-CGAU |||:: || |:|||||| || CUGUGGCACAG-GGUGUGCUGGCA- Spsb2; Ssb2 rno-miR-18 7 23 AUAGACGUGAUCUACGUGGAAU |||| :|:||::|: ----GGCACAGGGUGUGCUG-- Spsb2; Ssb2 rno-miR-199a 36 62 -CUUGUCCAUCAGACUUGUGAC--CC- |:||||||:| ::||||| || GGGACAGGUGGAGA-GGCACUGCUGGC Spsb2; Ssb2 rno-miR-207 11 54 UUCCCU-----CC-----------UCUCGGU---CCUCUUCG |||| || :|:| || |||||:|| CAGGGUGUGCUGGCACCCUACCGUGGGGACAGGUGGAGAGGCA Spsb2; Ssb2 rno-miR-20b 153 170 UGGACGUGAUACUCGU-GAAAC- :||:|| ||| ||||| -----GGCUGUG-GCAGCUUUGG Spsb2; Ssb2 rno-miR-24 53 90 -GACAA--GGA-------------CGA-CUUGACUCGGU ||| ||| ||| ||:||||| ACUGCUGGCCUAGACAACUUAAAAGCUGGAGCUGAGG-- Spsb2; Ssb2 rno-miR-291-3p 18 57 CCGUGUGU---------------UUCACCU--UCGUGAAA || :|| |:||||| :||||| UGCUGGCACCCUACCGUGGGGACAGGUGGAGAGGCACUG- Spsb2; Ssb2 rno-miR-292-3p 22 57 -UGUGAGUUUUGG-----------ACCG--CCGUGAA :||| | ||| ||| |||||| GGCACCCU--ACCGUGGGGACAGGUGGAGAGGCACUG Spsb2; Ssb2 rno-miR-296 76 101 -UGUCCUA-ACUCCC--CC-CCGGGA :| ||| |||||| || |||: AGCUGGAGCUGAGGGAAGGAGGCUG- Spsb2; Ssb2 rno-miR-324-3p 15 48 -GGUCG-UCGUGG------ACCCCG--UCACC- : || :||||| ||||| :|||| GUGUGCUGGCACCCUACCGUGGGGACAGGUGGA Spsb2; Ssb2 rno-miR-324-5p 7 47 -UGUGG-UUAC--------GGGAU----CCCCUA--CGC- :||| ::|| ||||| ||||| |:| GGCACAGGGUGUGCUGGCACCCUACCGUGGGGACAGGUGG Spsb2; Ssb2 rno-miR-329 5 21 UUUUUCCAAUCGA--CCCACACAA |:|| ||||||| -------GUGGCACAGGGUGUGC- Spsb2; Ssb2 rno-miR-330 147 170 AGAGACGUCCGGGACA--CGAAACG || :||||: || |||||| --ACUAUAGGCUGUGGCAGCUUUGG Spsb2; Ssb2 rno-miR-337 46 90 -UUUCCGUA------GUAUAU-------------CCUCGACUU |:||||| | || ||||||||: GAGAGGCACUGCUGGCCUAGACAACUUAAAAGCUGGAGCUGAGG Spsb2; Ssb2 rno-miR-338 66 104 AGUUG--UUUUAG----UGACUA--------CGACCU- |||| |||| :|||| |||||| ACAACUUAAAAGCUGGAGCUGAGGGAAGGAGGCUGGAC Spsb2; Ssb2 rno-miR-339 12 48 ACUCGAG-GACC------------UCCUGUCC-CU- |:|: |||| :||||||| |: AGGGUGUGCUGGCACCCUACCGUGGGGACAGGUGGA Spsb2; Ssb2 rno-miR-343 77 99 AGACC-CGUGUGCCUCCCUCU- |||| || | ||| ||||: GCUGGAGCUGAGGGAAGGAGGC Spsb2; Ssb2 rno-miR-345 7 44 -CGUGA-CCUGAU---------------CCCCAGUCGU |||| || |: |||| ||| GGCACAGGGUGUGCUGGCACCCUACCGUGGGGACAGG- Spsb2; Ssb2 rno-miR-346 41 70 -UCUCCG-UCCGUGA-GUCCG--UCUGU- :| || ||||||| | ||| ||||| AGGUGGAGAGGCACUGCUGGCCUAGACAA Spsb2; Ssb2 rno-miR-347 12 43 ACCCGCUGGGUC-----------UCCCUGU- |||:| |::| :|||||| AGGGUGUGCUGGCACCCUACCGUGGGGACAG Spsb2; Ssb2 rno-miR-34a 37 60 -UUGUUGGUCGAUUCUGUGACGGU :|||: ::| :||:||||||: GGACAGGUGGA-GAGGCACUGCUG Spsb2; Ssb2 rno-miR-34c 39 60 CGUUAGUCGAUUGA--UGUGACGGA ||| |:: :||||||: ----ACAGGUGGAGAGGCACUGCUG Spsb2; Ssb2 rno-miR-378 7 47 -UGUGUCC---------------UGG-ACCUCAGUCCUC- :|||||| ||| |||:| |||| | GGCACAGGGUGUGCUGGCACCCUACCGUGGGGACAGGUGG Spsb2; Ssb2 rno-miR-382 47 74 -CUUAG-GUGGUGC----UUGUUGAAG ||: | | | :||||||| AGAGGCACUGCUGGCCUAGACAACUUA Spsb2; Ssb2 rno-miR-412 20 50 UGCCGAU------CACCUG-GUCCACUUCA :||| ||||: ||||||:|| CUGGCACCCUACCGUGGGGACAGGUGGAGA Spsb2; Ssb2 rno-miR-449 29 60 -UGGU-CGAUUGUUA-------UGUGACGGU |||: | :|||: :||||||: UACCGUGGGGACAGGUGGAGAGGCACUGCUG Spsb2; Ssb2 rno-miR-497 6 26 AUGUUUG-GUGUCACACGA-CGAC ::| || :||||||| || ---UGGCACAGGGUGUGCUGGCA- Spsb2; Ssb2 rno-miR-93 27 57 -GAUGGACGUGCUUG---------UCGUGAAAC ||||| |: |:|| :||||| CCUACC-GUGGGGACAGGUGGAGAGGCACUG-- Spsb2; Ssb2 rno-miR-10a 1 17 guguuuAAGCCUAGAUGUCCCAu | :|| | ||||||| ---cccTGTGG--C-ACAGGGTg Spsb2; Ssb2 rno-miR-133a 80 106 ugUCGA---CCAACUUCC--CCUGGuu |||| || |:||| ||||| ggAGCTGAGGGAAGGAGGCTGGACCcc Spsb2; Ssb2 rno-miR-133b 81 106 aUCGA---CCAACUUCC--CCUGGuu |||| || |:||| ||||| gAGCTGAGGGAAGGAGGCTGGACCcc Spsb2; Ssb2 rno-miR-142-3p 35 58 agguauUUCAUC-CUUUGUGAUGu |:||:| ||::||||:| ggggacAGGTGGAGAGGCACTGCt Spsb2; Ssb2 rno-miR-145 48 83 uUCCCUAAGGACC----C--------UUUUGACCUg ||| | | |||| | |||:||||| gAGGCACTGCTGGCCTAGACAACTTAAAAGCTGGAg Spsb2; Ssb2 rno-miR-152 36 57 ggguucaagacaguaCGUGACu |||||| gggacaggtggagagGCACTGc Spsb2; Ssb2 rno-miR-15b 4 25 ACAUUUGGUACUACACGACgau |||:: || |:||||||| TGTGGCACAGGGTGTGCTGgca Spsb2; Ssb2 rno-miR-18 3 30 auagaCGUGAUCUA------CGUGGAAU |||| :|:| ||||| || ctgtgGCACAGGGTGTGCTGGCACCCTA Spsb2; Ssb2 rno-miR-199a 37 58 CUUGUCCAUCAGACU-UGUGACcc |:||||||:| || :||||| GGACAGGTGG--AGAGGCACTGct Spsb2; Ssb2 rno-miR-207 31 52 uuCCCUCCUCUCGGUCCUCUUCG | |:||| || : |||||:|| ccGTGGGGACAGGT-GGAGAGGC Spsb2; Ssb2 rno-miR-20b 146 168 ugGACGU--GAUACUCGU-GAAAC || :| ||:|| ||| ||||| taCTATAGGCTGTG-GCAGCTTTG Spsb2; Ssb2 rno-miR-22 142 166 UGUCAAGA-AGUUG--ACCGUCGAA |:: | || | ::| ||||||||| ATGATACTATAGGCTGTGGCAGCTT Spsb2; Ssb2 rno-miR-24 69 91 gacaaggaCGA-CUUGACUCggu ||| ||:||||| acttaaaaGCTGGAGCTGAGgga Spsb2; Ssb2 rno-miR-291-3p 36 57 CCGUGUGUUUCAC--CUUCGUGAaa || || |:||| ||:||||| GGGAC---AGGTGGAGAGGCACTgc Spsb2; Ssb2 rno-miR-291-3p 7 29 CCGUGUGUUUCACCUUCGUGaaa |||||| :: ||| :|||| GGCACAGGGTGTGCTGGCACcct Spsb2; Ssb2 rno-miR-292-3p 6 28 uguGAGUUUUGGACCGCCGUGaa | ||:::: || :||||| tggCACAGGGTGTGCTGGCACcc Spsb2; Ssb2 rno-miR-292-3p 34 56 ugugaguuuuggaccgCCGUGAa |||||| tggggacaggtggagaGGCACTg Spsb2; Ssb2 rno-miR-296 86 106 uguCCUAACUCCCCCCCGGGa ||| |||| || ||| gagGGAAGGAGGCTGGACCCc Spsb2; Ssb2 rno-miR-324-3p 20 46 GGUCGUCG--UGG-ACCCC-GU-CACC |::||| | ||| ||||| || |||| CTGGCACCCTACCGTGGGGACAGGTGG Spsb2; Ssb2 rno-miR-324-5p 1 21 uguGGUUACGGGAUCCCCUACGc || :|| | |||| :||| --cCCTGTGGCACAGGGTGTGCt Spsb2; Ssb2 rno-miR-329 1 21 uuuuuccaaucGACCCACACaa | ||||||| -ccctgtggcaCAGGGTGTGct Spsb2; Ssb2 rno-miR-330 145 169 agaGACGUCCGGGAC--ACGAAACg || :||||: || |||||| ataCTATAGGCTGTGGCAGCTTTGg Spsb2; Ssb2 rno-miR-337 62 88 uuUCCGUAGUAUAU----CCUCGACUu || || | || | |||||||| ctAGACAACTTAAAAGCTGGAGCTGAg Spsb2; Ssb2 rno-miR-338 80 102 agUUGUUUUAGUGACUACGACCU |:| :|: | || |||||| ggAGCTGAGGGAAGGAGGCTGGA Spsb2; Ssb2 rno-miR-339 16 45 ACUCGA-----GGA---C-CUCCUGUCCcu || ||| ||| | |:||||||| TGTGCTGGCACCCTACCGTGGGGACAGGtg Spsb2; Ssb2 rno-miR-339 1 16 acucgaGGACCUCCUGUCCCu |||| :| |||||| -----cCCTGTGGCACAGGGt Spsb2; Ssb2 rno-miR-345 17 44 CGUGACC-U--GAU----CCCCAGUCgu |::|||| | ||| |||| ||| GTGCTGGCACCCTACCGTGGGGACAGgt Spsb2; Ssb2 rno-miR-346 45 68 uCUCCGUCCGUGA-GUCCG--UCUGU ||| ||||||| | ||| ||||| gGAG--AGGCACTGCTGGCCTAGACA Spsb2; Ssb2 rno-miR-347 34 55 ACCC--G-CUGGGUCUCCCUGu |||| | |:: ||||| || TGGGGACAGGTGGAGAGGCACt Spsb2; Ssb2 rno-miR-34a 38 59 uUGUUGGUCGAUUCUGUGACGgu |||: ::| :||:|||||| gACAGGTGG-AGAGGCACTGCtg Spsb2; Ssb2 rno-miR-34c 35 59 cguuaGUCGA--UUGAUGUGACGga ||| | |: :|||||| ggggaCAGGTGGAGAGGCACTGCtg Spsb2; Ssb2 rno-miR-378 23 45 uGUGUCCUGG-ACCUCAGUCCuc ||| ||| |||:| |||| gCACCCTACCGTGGGGACAGGtg Spsb2; Ssb2 rno-miR-412 24 49 ugccGAU--CA-CCUGGUCCACUUCa ||| || ||: ||||||:|| caccCTACCGTGGGGACAGGTGGAGa Spsb2; Ssb2 rno-miR-449 38 59 ugGUCGAUUGUUAUGUGACGgu ||| |:: :| :|||||| gaCAGGTGGAGAGGCACTGCtg Spsb2; Ssb2 rno-miR-497 2 25 auguuugGUGU--CACACGACgac |||| |||||||| cctgtggCACAGGGTGTGCTGgca Spsb2; Ssb2 rno-miR-93 28 58 GAUGG-AC----GU--GCUUGU-CGUGAaac ||||| || || :|:| | ||||| CTACCGTGGGGACAGGTGGAGAGGCACTgct Spsb2; Ssb2 rno-miR-22 159 166 UGUCAAGAAGUUG----------------------ACCGUCGAA ||| :|| ||||||||| -CAGGAACAAGACAUAGAAAUGAUACUAUAGGCUGUGGCAGCUUU Spsb2; Ssb2 rno-miR-337 81 88 -UUUCCGUAGUAUAU--------------------CCUCGACUU |:||||| | ||||||||: GAGAGGCA-CUGCUGGCCUAGACAACUUAAAAGCUGGAGCUGAGG Spsb2; Ssb2 rno-miR-382 66 73 -----------------CUUAGGUGGUG-C-----UUGUUGAAG ||: ||| | | :||||||| CCGUGGGGACAGGUGGAGAGG-CACUGCUGGCCUAGACAACUUA

DNA & RNA Element - RAID2 Gene Name RAID ID Interactor 1 Category 1 ID 1 Interactor 2 Category 2 ID 2 Methods Score Spsb2 RAID00254121 rno-miR-320-3p miRNA MIMAT0000903 Spsb2 mRNA 297592 Prediction 0.1828 Spsb2 RAID01410974 rno-miR-216a-5p miRNA MIMAT0000886 Spsb2 mRNA 297592 Prediction 0.1828 Spsb2 RAID01440714 rno-miR-382-5p miRNA MIMAT0003201 Spsb2 mRNA 297592 Prediction 0.1828 Spsb2 RAID02239186 rno-miR-22-3p miRNA MIMAT0000791 Spsb2 mRNA 297592 Prediction 0.2202 Spsb2 RAID02988080 rno-miR-146a-3p miRNA MIMAT0017132 Spsb2 mRNA 297592 Prediction 0.1828 Spsb2 RAID03270964 rno-miR-10a-5p miRNA MIMAT0000782 Spsb2 mRNA 297592 Prediction 0.1828