PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Gnb1 Sumo3 22082260 biogrid exp G G G G G G G G Gnb1 Gnb1 19834914 intact exp G G G G G G G G Snca Gnb1 16854843 biogrid exp G G G G G G Slc2a4 Gnb1 16396496 intact exp G G G Gnb1 Fndc1 16407149 dip exp Gnb1 Wasf1 16530190 mint,intact exp Cacna1a Gnb1 15953418 biogrid exp, ortho G Gnai3 Gnb1 ortho Gnb1 Mrgprx1 ortho Jun Gnb1 ortho G G G G G G G G Protein Gng13, RCG32756 Gnb1 ortho Gnb1 Ccdc8 ortho G G Gnb1 Aarsd1 ortho G G G G G G G G Gng7 Gnb1 ortho G G G G G G G G Gnb1 Pan2 ortho G G G G G G G G Gnb1 Rasd2 ortho G G G Protein Vav3 Gnb1 ortho Pfdn5_predicted Gnb1 ortho G G G G G G G G Ptk2 Gnb1 ortho G G G G G G G G Gnb1 Ywhaz ortho G G G G G G G G Gnb1 Pdlim7 ortho G G G Adrbk1 Gnb1 ortho G G G G G G G G Arhgef18_predicted Gnb1 ortho Pak1 Gnb1 ortho G G G G G G G G Abl2_mapped Gnb1 ortho G G G G G G G Akt1 Gnb1 ortho G G G G G G G G Gnb1 Kalrn ortho G G G G Gnb1 Ywhae ortho G G G G G G G G Gnb1 Cd3z ortho G G Gnb1 Spag1 ortho Afp Gnb1 ortho G Gnb1 Grin2b ortho G G Gnb1 Ntn1 ortho G G G G G G Mlf1_predicted Gnb1 ortho Adrb2 Gnb1 ortho G Atp6v1b1_predicted Gnb1 ortho Ncf2 Gnb1 ortho Map3k3_predicted Gnb1 ortho G G G G G G G Guanine nucleotide-binding protein subunit gamma Gnb1 ortho G G G G G G G G Gnb1 Gna12 ortho G G G G G G G G Gnb1 Gnas ortho G G G G G G G G Gnb1 Rap1a ortho G G G G G G G G Tbxa2r Gnb1 ortho G Adra2a Gnb1 ortho Stip1 Gnb1 ortho G G G G G G G G Protein Atp6v1a, RCG52629 Gnb1 ortho G G G G G G G G Arrb1 Gnb1 ortho Gnb1 Gnaq ortho Gnb1 Atxn10 ortho G G G G G G G G Cyfip1_predicted Gnb1 ortho G G G G G G G G Gnb1 Vamp2 ortho G G G G G G G G Gnb1 Cct5 ortho G G G G G G G G ATP-binding cassette, sub-family E (OABP), member 1, Protein Abce1 Gnb1 ortho G G G G G G G G Gnb1 Mcf2l ortho Protein Radil, RCG42648, isoform CRA_a Gnb1 ortho G G G Cox4i1 Gnb1 ortho G G G G G G G G Gnb1 Cacna1b ortho G G G Gnb1 Gnb2l1 ortho G G G G G G G G Gnb1 Ripk3 ortho G G G Dlg4 Gnb1 ortho G G G G G G Gnb1 Hdac4 ortho G Protein Nfx1, RCG55154 Gnb1 ortho Gnb1 Disc1 ortho Mlf2_predicted Gnb1 ortho G G G G G G G G Protein Rptor Gnb1 ortho G G G G G G G G Vcam1 Gnb1 ortho Gnb1 Gna11 ortho G G G Prnp Gnb1 ortho G G G G G G G G Nr3c1 Gnb1 ortho G G G G G G G G Gnb1 Dync1i1 ortho G G G G G Gnb1 Fyn ortho G G G G G Cacna1c Gnb1 ortho G G G G G G Esr1 Gnb1 ortho Gnb1 Gng8 ortho Pth1r Gnb1 ortho G G Gnb1 Avpr2 ortho G G G G Gnb1 Met ortho G Htt Gnb1 ortho G G G G G G G Elavl4 Gnb1 ortho G G G G G G G G Ntrk1 Gnb1 ortho Gnb1 Tekt2 ortho Gnb1 Kcnj3 ortho G G G G G G Gnb1 Synpo ortho G G Pou2f1 Gnb1 ortho Gnb1 Anterior pharynx defective 1 homolog A (C. elegans), Anterior pharynx defective 1a homolog (C. elegans), isoform CRA_b, Protein Aph1a ortho G G G G G G G G Gnb1 Hspa8 ortho Gnb1 Rasd1 ortho G G G G G Gnb1 Gng5 ortho G G G G G G G G Cav3 Gnb1 ortho Gnai2 Gnb1 ortho G G G G G G G G Gnb1 Psmd2 ortho G G G G G G G G Mtor Gnb1 ortho G G G G G G G G Protein Flad1 Gnb1 ortho G G G G G G G G Gnb1 Xpo1 ortho G G G G G G G G Gnb1 Ubqln1 ortho G G G G G G G G Mtnr1b Gnb1 ortho Gnb1 Pdcl ortho G G G G G G G G Gnai1 Gnb1 ortho G G G G Gnb1 Gnao1 ortho G G G G G G Plekhg2_predicted Gnb1 ortho G Mtnr1a Gnb1 ortho Gnb1 Epha7 ortho

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Cacna1a Gnb1 MI:0055(fluorescent resonance energy transfer)|MI:0055(fluorescent resonance energy transfer) 15953418 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_335297|BIOGRID_335296 prey|prey bait|bait Gnb1 Wasf1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 16530190 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint) UniProt_184158|MINT_78051|UniProt_184157|UniProt_85096|MINT_78050 prey|prey|prey|prey|prey bait|bait|bait|bait|bait Gnb1 Sumo3 MI:0004(affinity chromatography technology) 22082260 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_334353 prey bait Snca Gnb1 MI:0004(affinity chromatography technology) 16854843 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_335612 bait prey

PPI - HINT Gene A Gene B PMID Method Quality CACNA1A GNB1 15953418,15953418 0018,0055 LC SLC2A4 GNB1 16396496 0007 LC SNCA GNB1 16854843 0004 LC GNB1 FNDC1 16407149 0096 LC GNB1 WASF1 16530190,16530190 0006,0007 LC GNB1 SUMO3 22082260 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q5XIF4 P54311 SUMO3 GNB1 0.126 22082260 Q9Y2K9 P54311 STXBP5L GNB1 0.126 25002582 P54311 P22392 GNB1 NME2 0.454 12486122 Q5BJU7 P54311 WASF1 GNB1 0.376 16530190 P54311 P54282 GNB1 CACNA1A 0.523 15953418 P54311 P37377 GNB1 SNCA 0.126 16854843 P54311 P19357 GNB1 SLC2A4 0.126 16396496