PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Prkci Pard6a i2d exp Prkcz Pard6a i2d exp Pard6a Pard3 i2d exp Tgfbr1 Pard6a 20603020 intact exp

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q6B4M5 enzymatic study 21262463 direct interaction X 2 Q6B4M5 pull down 15723051 association C 5 Q6B4M5 pull down 15723051 association C 5 Q6B4M5 anti bait coimmunoprecipitation 18621709 physical association X 2 Q6B4M5 anti bait coimmunoprecipitation 20603020 physical association C 3 P80204 Q6B4M5 confocal microscopy 20603020 colocalization X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Pard6a Mpp5 MI:0006(anti bait coimmunoprecipitation) 18621709 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) MI:0465(dip) DIP_5225 - - Tgfbr1 Pard6a MI:0663(confocal microscopy)|MI:0663(confocal microscopy) 20603020 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0403(colocalization)|MI:0915(physical association) (intact)|(intact) UniProt_184985|UniProt_184983 neutral component|bait neutral component|prey

PPI - HINT Gene A Gene B PMID Method Quality PRKCI PARD6A 15723051 0019 LC PRKCZ PARD6A 12813044 0018 LC PARD6A PARD3 15723051,15723051 0405,0019 LC MPP5 PARD6A 18621709 0006 LC TGFBR1 PARD6A 20603020,20603020 0006,0663 LC PARD6A CDC42 15723051 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q6B4M5 B4F7E7 PARD6A MPP5 0.21 18621709 Q6B4M5 P80204 PARD6A TGFBR1 0.309 20603020