PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Trim3 Myo5b 16338934 intact exp G G G G Trim3 Actn4 i2d exp, ortho G G G G G G G G Trim3 Ywhaz ortho G G G G G G G G LOC316395 Trim3 ortho Trim3 Hgs ortho G G G G G G G G Trim3 Myo5a ortho G G G G G G G G Trim3 Ube2d2b ortho LOC683206 Trim3 ortho Tead2_mapped Trim3 ortho G G G G G G G G Hip2_predicted Trim3 ortho G G G G G G G G Kinesin-like protein Trim3 ortho G Trim3 Trim3 ortho G G G G G G G G Ube2g2_predicted Trim3 ortho G G G G G G G G Trim3 Ywhab ortho G G G G G G G G Cul3 Trim3 ortho G G G G G G G G Trim3 Pdha1 ortho G G G G G G G G Trim3 Ywhae ortho G G G G G G G G Trim3 Cyclin-dependent kinase inhibitor 1A, Cyclin-dependent kinase inhibitor 1A (P21, Cip1), P21, P21 protein, Protein Cdkn1a ortho G G G G G G G Trim3 rCK1e ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O70277 - 10673389 - X 2 O70277 - 10673389 - X 2 O70277 P70569 anti tag coimmunoprecipitation 16338934 physical association X 2 O70277 Q9QXQ0 two hybrid 10673389 - X 2 O70277 Q9QXQ0 coimmunoprecipitation 10673389 - X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Trim3 Myo5b MI:0006(anti bait coimmunoprecipitation) 16338934 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (intact) UniProt_182763 prey bait

PPI - HINT Gene A Gene B PMID Method Quality TRIM3 ACTN4 10673389,10673389 0018,0019 LC TRIM3 MYO5B 16338934 0007 LC