PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Usp34 Uba52 22043315 biogrid exp G G G G G G G G Trim21_predicted Uba52 ortho Protein Ripk2, RCG54865 Uba52 ortho Vcp Uba52 ortho G G G G G G G G Uba52 Nbr1 ortho Got1 Uba52 ortho G G G G G G G G Antisecretory factor, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 4, isoform CRA_a, Protein Psmd4 Uba52 ortho G G G G G G G G PTEN/MMAC1 Uba52 ortho G G G G G Uba52 Dll1 ortho Gabrg2 Uba52 ortho Mdm2_predicted Uba52 ortho G G G G G Uba52 Uimc1 ortho G G G G G G G G Sqstm1 Uba52 ortho G G G G G G G G Irak1_predicted Uba52 ortho G G G G G G G G Uba52 Ralbp1 ortho G G G G G G G G Tnfrsf4 Uba52 ortho G G Uba52 Crtc2 ortho G G G G G G G G Ywhab Uba52 ortho G G G G G G G G Epn1 Uba52 ortho G G Uba52 Park2 ortho Nanog homeobox, Protein Nanog Uba52 ortho Tp53 Uba52 ortho G G G G G G G G Dlg4 Uba52 ortho G G G G G G Cftr Uba52 ortho Cd3e_predicted Uba52 ortho Uba52 Tab2 ortho G G G G G G G G Axin1 Uba52 ortho G G G G G G G G Traf3_predicted Uba52 ortho G G G G G G G G Uba52 Fzd5 ortho Brca1 Uba52 ortho G Uba52 RelA ortho G G G G G G G G Gmnn_predicted Uba52 ortho Traf6 Uba52 ortho Uba52 Egln3 ortho G G G G G Sncaip_predicted Uba52 ortho Irs1 Uba52 ortho RGD1311099_predicted Uba52 ortho Uba52 Fzd4 ortho G G Atxn3 Uba52 ortho Uba52 Pgls ortho G G G G G G G G Foxp3 Uba52 ortho Myl12b Uba52 ortho G G G G G G G G Uba52 Nfe2 ortho G Protein Nphp4, RCG31055, isoform CRA_a Uba52 ortho Uba52 Ido1 ortho Ripk1_predicted Uba52 ortho G G G G G S1pr2 Uba52 ortho G G G Ywhae Uba52 ortho G G G G G G G G Uba52 Cttn ortho G G G G G G G G Uba52 Fbxo32 ortho Protein Ndfip2 Uba52 ortho G G G G G G G G Uba52 Ywhaz ortho G G G G G G G G Anxa5 Uba52 ortho G G G G G G G G Akap1 Uba52 ortho G G G G Uba52 Notch1 ortho G G G G G G G Cdk5r1 Uba52 ortho G Protein Ltn1 Uba52 ortho Hist1h3e Uba52 ortho Uba52 Ikbkg ortho Uba52 Ncstn ortho G G G G G G G G Protein Irak4 Uba52 ortho Protein LOC691153, RCG33922 Uba52 ortho Uba52 Met ortho G Myog Uba52 ortho G G G Akt1 Uba52 ortho G G G G G G G G Uba52 Anxa2 ortho G G G G G G G G Uba52 Cdc20 ortho G G G Uba52 Ecsit ortho G G G G G G G G Insr Uba52 ortho G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants F1M625 P62986 enzymatic study 22043315 direct interaction X 2 P62986 anti bait coimmunoprecipitation 21808025 - C 3 O35254 P62986 anti bait coimmunoprecipitation 21572988 physical association X 2 Q62986 P62986 anti bait coimmunoprecipitation 21808025 physical association X 2 Q62986 P62986 anti bait coimmunoprecipitation 21808025 physical association X 2 B2B9B0 P62986 anti bait coimmunoprecipitation 21113149 physical association X 2 P62986 anti bait coimmunoprecipitation 21808025 - C 4 P62986 B1WBR1 anti tag coimmunoprecipitation 21572988 physical association X 2 P06211 P62986 anti bait coimmunoprecipitation 21808025 physical association X 2 P06211 P62986 anti bait coimmunoprecipitation 21808025 physical association X 2 P06211 P62986 anti bait coimmunoprecipitation 21808025 physical association X 2 P06211 P62986 anti bait coimmunoprecipitation 21808025 physical association X 2 P06211 P62986 anti bait coimmunoprecipitation 21808025 physical association X 2 P51639 P62986 anti bait coimmunoprecipitation 15919082 physical association X 2 P61810 P62986 anti tag coimmunoprecipitation 17036052 physical association X 2 Q9NP59 P62986 anti tag coimmunoprecipitation 17541408 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P62986 F1M625 UBA52 USP46 {ECO:0000312|RGD:1564808} 0.309 22043315