PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Protein Ss18 21454665 biogrid exp G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Sumo3 22082260 biogrid exp, ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Sumo1 21454665 biogrid exp, ortho G G G Pias1 Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Gadd45g ortho G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Protein Btaf1 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Htt ortho G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Gfi1 ortho G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Prmt5_predicted ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Protein Skil ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Zw10 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Hif1a ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Tada3 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Impdh2 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Men1 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Lrif1 ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Ikbkg ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Pde4d ortho G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Sh3gl3 ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Ube2i ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Smad3 ortho G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Aldoa ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Map1lc3a ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Parp1 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Pde4dip ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Elavl4 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Interferon regulatory factor 3, Interferon regulatory factor 3, isoform CRA_c, Protein Irf3 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Immt ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Coil ortho G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Brca1 ortho G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Cebpd ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Protein Zmiz2, Similar to D11Bwg0280e protein, isoform CRA_c ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Phgdh ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Hnrpul1_predicted ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Mageh1 ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Smad2 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Prkcz ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Lef1 ortho G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Nr4a2 ortho G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 DNA-binding protein SATB ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Protein Tcerg1 ortho G G G Eif5b Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Smad1 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Bard1 ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Vhl ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Sumo2 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Ar ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Erbb4 ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Urkl1_predicted ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Top2a ortho G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Prpf40a_predicted ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Xrcc5 ortho G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Kpnb1 ortho G G G Hdac2 Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Hnf4a ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Ubc ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Smad7 ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Interferon regulatory factor 7, Protein Irf7 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 CDC-like kinase 1, isoform CRA_b, Protein Clk1 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Protein LOC100911180 ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Hdac1 ortho G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Mdc1 ortho G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Pde4a ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Axin1 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Ptn ortho G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Hip2_predicted ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Herc2_predicted ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 LOC683746 ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Actn1 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Mprip ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Lamp2 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 RelA ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Krt18 ortho G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Plag1 ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Protein Trim32, Tripartite motif protein 32 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Protein Serpina5, Serine (Or cysteine) peptidase inhibitor, clade A, member 5 ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Vim ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Tgm2 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Smad4 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Ets1 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Tcf4 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Trim27 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Zhx1 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Kntc1_predicted ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Phf11 ortho Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Nefl ortho G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Optn ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Oaz1 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Tp53 ortho G G G Pias4 protein, Protein Pias4, Protein inhibitor of activated STAT, 4 Pias2 ortho G G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Sumo3 Pias4 MI:0004(affinity chromatography technology) 22082260 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_334384 bait prey Ss18 Pias4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21454665 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_334420|BIOGRID_334423 bait|prey prey|bait Sumo1 Pias4 MI:0004(affinity chromatography technology) 21454665 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_334422 prey bait Pias4 rplB MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21454665 taxid:10116(Rattus norvegicus) taxid:691903() MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_334424|BIOGRID_334421 bait|prey prey|bait

PPI - HINT Gene A Gene B PMID Method Quality PIAS4 SS18 21454665 0004 LC PIAS4 SUMO1 21454665 0004 LC PIAS4 SUMO3 22082260 0004 LC