PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Klhl17 Syngap1 16054660 mint,intact exp Klhl17 Pdzk1 16054660 mint,intact exp Cul1_predicted Klhl17 17062563 biogrid exp Actb Klhl17 16054660 mint,intact exp Grik2 Klhl17 17062563 biogrid exp Grik1 Klhl17 17062563 biogrid exp Ubc Klhl17 17062563 biogrid exp Dlg4 Klhl17 16054660,12063253 biogrid,mint,intact exp Cul3 Klhl17 17062563 biogrid exp, ortho Dcn Klhl17 ortho Klhl17 Klhl17 ortho Actc1 Klhl17 ortho Actg1 Klhl17 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8K430 affinity chromatography technology 17062563 physical association X 2 Q8K430 Q63429 affinity chromatography technology 17062563 physical association X 2 Q8K430 P31016 biochemical 12063253 colocalization X 2 Q8K430 affinity chromatography technology 17062563 physical association X 2 Q8K430 affinity chromatography technology 17062563 physical association X 2 Q8K430 affinity chromatography technology 17062563 physical association X 2 Q8K430 Q5T2W1 two hybrid 12063253 direct interaction X 2 Q8K430 pull down 12063253 direct interaction X 2 Q8K430 P31016 anti bait coimmunoprecipitation 16054660 physical association X 2 Q8K430 P31016 anti bait coimmunoprecipitation 16054660 physical association X 2 Q8K430 P60711 imaging technique 16054660 colocalization X 2 Q8K430 P60711 cosedimentation 16054660 direct interaction X 2 Q8K430 Q9JJ40 anti tag coimmunoprecipitation 16054660 physical association X 2 Q8K430 Q9JJ40 anti tag coimmunoprecipitation 16054660 physical association X 2 Q8K430 Q9JJ40 anti tag coimmunoprecipitation 16054660 physical association X 2 Q8K430 Q9JJ40 anti tag coimmunoprecipitation 16054660 physical association X 2 Q8K430 Q9JJ40 anti tag coimmunoprecipitation 16054660 physical association X 2 Q8K430 Q9JJ40 anti tag coimmunoprecipitation 16054660 physical association X 2 Q8K430 Q9JJ40 anti tag coimmunoprecipitation 16054660 physical association X 2 Q8K430 Q9JJ40 anti tag coimmunoprecipitation 16054660 physical association X 2 Q8K430 Q9JJ40 anti bait coimmunoprecipitation 16054660 physical association X 2 Q8K430 Q9QUH6 anti bait coimmunoprecipitation 16054660 physical association X 2 Q8K430 Q9QUH6 anti bait coimmunoprecipitation 16054660 physical association X 2 Q8K430 Q9JJ40 two hybrid 16054660 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Grik2 Klhl17 MI:0004(affinity chromatography technology) 17062563 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_335160 bait prey Actb Klhl17 MI:0007(anti tag coimmunoprecipitation)|MI:0428(imaging technique)|MI:0007(anti tag coimmunoprecipitation)|MI:0428(imaging technique) 16054660 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0407(direct interaction)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0407(direct interaction) (intact)|MI:0471(mint)|(intact)|MI:0471(mint) UniProt_183821|MINT_80495|UniProt_183783|MINT_80494 neutral component|neutral component|neutral component|neutral component neutral component|neutral component|neutral component|neutral component Klhl17 Cul3 MI:0004(affinity chromatography technology) 17062563 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_335158 prey bait Ubc Klhl17 MI:0004(affinity chromatography technology) 17062563 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_335162 prey bait Klhl17 Cul1 MI:0004(affinity chromatography technology) 17062563 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_335159 prey bait Klhl17 Syngap1 MI:0428(imaging technique)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0428(imaging technique) 16054660 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact)|(intact)|MI:0471(mint) MINT_80469|UniProt_183812|UniProt_183811|MINT_80470 bait|prey|bait|prey prey|bait|prey|bait Grik1 Klhl17 MI:0004(affinity chromatography technology) 17062563 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association) (biogrid) BIOGRID_335161 bait prey Dlg4 Klhl17 MI:0007(anti tag coimmunoprecipitation)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0007(anti tag coimmunoprecipitation) 16054660 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0471(mint)|(intact) UniProt_183810|MINT_80468|MINT_80467|UniProt_183809 prey|prey|bait|bait bait|bait|prey|prey Klhl17 Pdzk1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique) 16054660 taxid:10116(Rattus norvegicus) taxid:10116(Rattus norvegicus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint) UniProt_165459|UniProt_183818|UniProt_183785|UniProt_183786|UniProt_183796|UniProt_183797|UniProt_183804|UniProt_165470|UniProt_183795|UniProt_183794|UniProt_183793|UniProt_183792|UniProt_165477|UniProt_165465|UniProt_165466|UniProt_165467|UniProt_165458|UniProt_165468|UniProt_165469|MINT_80488|MINT_80487|MINT_80486|MINT_80485|MINT_80484|MINT_80459|MINT_80475|MINT_80489|MINT_80460|MINT_80461 bait|prey|prey|bait|prey|bait|prey|bait|prey|bait|bait|prey|prey|prey|bait|bait|prey|prey|prey|prey|prey|bait|bait|prey|prey|prey|bait|bait|prey prey|bait|bait|prey|bait|prey|bait|prey|bait|prey|prey|bait|bait|bait|prey|prey|bait|bait|bait|bait|bait|prey|prey|bait|bait|bait|prey|prey|bait

PPI - HINT Gene A Gene B PMID Method Quality DLG4 KLHL17 12063253 0401 LC ACTB KLHL17 16054660,16054660 0027,0428 LC KLHL17 PDZK1 16054660,16054660,16054660 0006,0018,0007 LC CUL1 KLHL17 17062563 0004 LC CUL3 KLHL17 17062563 0004 LC GRIK1 KLHL17 17062563 0004 LC DLG4 KLHL17 16054660,12063253 0006,0401 LC GRIK2 KLHL17 17062563 0004 LC ACTB KLHL17 16054660,16054660 0027,0428 LC UBC KLHL17 17062563 0004 LC KLHL17 PDZK1 16054660,16054660,16054660 0006,0018,0007 LC KLHL17 SYNGAP1 16054660 0006 LC KLHL17 UPI0001551964 17062563 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8K430 P22756 KLHL17 GRIK1 0.21 17062563 Q8K430 Q5T2W1 KLHL17 PDZK1 0.309 12063253 Q8K430 Q63429 KLHL17 UBC 0.21 17062563 Q9JJ40 Q8K430 PDZK1 KLHL17 0.659 16054660 Q9QUH6 Q8K430 SYNGAP1 KLHL17 0.21 16054660 Q8K430 P60711 KLHL17 ACTB 0.396 16054660 Q8K430 P31016 KLHL17 DLG4 0.309 16054660,12063253 Q8K430 B5DF89 KLHL17 CUL3 0.21 17062563 Q8K430 P42260 KLHL17 GRIK2 0.21 17062563