PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Rad23b Nploc4 19182904 biogrid exp, ortho G G G G G G G G Ufd1l Nploc4 10811609 biogrid,i2d exp, ortho G G G G G G G G Nsfl1c Nploc4 10811609 biogrid exp, ortho G G G G G G G G Vcp Nploc4 10811609 biogrid exp, ortho G G G G G G G G Cdk5 Nploc4 ortho G G G G G G G Adsl_predicted Nploc4 ortho G G G G G G G G Vimp Nploc4 ortho G G G G G G G G Pkm Nploc4 ortho Faf1 Nploc4 ortho G G G G G G G G Zfand2b Nploc4 ortho G G G G G Mtpn Nploc4 ortho G G G G G G G G Elavl4 Nploc4 ortho G G G G G G G G Protein Tmem62 Nploc4 ortho Ntrk1 Nploc4 ortho Ubqln2_predicted Nploc4 ortho G G G G G G G G tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit Wdr4 Nploc4 ortho Protein Srp14, RCG26543, isoform CRA_b, Signal recognition particle 14 Nploc4 ortho G G G G G G G G Plaa Nploc4 ortho G G G G G G G G Nploc4 Nploc4 ortho G G G G G G G G Faf2 Nploc4 ortho LOC363332 Nploc4 ortho G G G G G G G G Dnaaf5 Nploc4 ortho Nploc4 Flot1 ortho G G G G G G G G Ubc Nploc4 ortho Nploc4 Ccnh ortho G G G G G G G G RGD1309519_predicted Nploc4 ortho Rpa2 Nploc4 ortho G G G Protein Mrpl19, Ribosomal protein, mitochondrial, L15 Nploc4 ortho G G G G G G G G Ptprf Nploc4 ortho G G G G G G G RGD1310211_predicted Nploc4 ortho G G G G G G G G Mitochondrial ribosomal protein S9, Mrps9 protein, Protein Mrps9 Nploc4 ortho G G G G G G G G Cd2ap Nploc4 ortho Gars Nploc4 ortho G G G G G G G G Sh3kbp1 Nploc4 ortho G G G G G G G G Eif4a3 Nploc4 ortho G G G G G G G G Ubl4a Nploc4 ortho G G G G G G G G Gzmk Nploc4 ortho G G G G G G G G Asns Nploc4 ortho G G G G G G G Ubxd6_predicted Nploc4 ortho Ufm1 Nploc4 ortho G G G G G G G G RGD1561600_predicted Nploc4 ortho Protein Dpp9 Nploc4 ortho G G G G G G G Protein Kcnk16, RCG41914, isoform CRA_b Nploc4 ortho Protein Ube3a Nploc4 ortho Protein Rprd1a Nploc4 ortho Mppe1 Nploc4 ortho Cap1 Nploc4 ortho G G G G G G G G Perilipin Nploc4 ortho G G G G G G G G Ptch Nploc4 ortho Ube2g2_predicted Nploc4 ortho G G G G G G G G Ccng1 Nploc4 ortho G G G G G G G G Protein Fblim1 Nploc4 ortho G G G G G G G G Nfkbia Nploc4 ortho G G G G G Nxf1 Nploc4 ortho G G G G G G G G Protein Mov10, RCG51996 Nploc4 ortho G G G G G Uba2 Nploc4 ortho G G G G G G G G Atp6v1b2 Nploc4 ortho G G G G G G G G FK506 binding protein 10, Protein Fkbp10, Similar to 65kDa FK506-binding protein, isoform CRA_a Nploc4 ortho G G G Eno1 Nploc4 ortho G G G G G G G G Picalm Nploc4 ortho G G G G G G G G Sae1 Nploc4 ortho G G G G G G G G Hnrpr Nploc4 ortho G G G G G G G G Vcpip1 Nploc4 ortho Mtmr12 Nploc4 ortho Uba1 Nploc4 ortho G G G G G G G G Smad1 Nploc4 ortho G G G G G G G G Usp34 Nploc4 ortho G G G G G G G G Coq6 Nploc4 ortho G G G G G Ubxn10 Nploc4 ortho Ccnd2 Nploc4 ortho G G G G G G G Itpr1 Nploc4 ortho G G G G G G G G Adrb2 Nploc4 ortho G Dctn1 Nploc4 ortho G G G G G G G G Lpp Nploc4 ortho LOC316395 Nploc4 ortho Lmna Nploc4 ortho G G G G G G G G Sprtn Nploc4 ortho Hnrnpk Nploc4 ortho Btrc Nploc4 ortho G G G G G G G G Ubxn11 Nploc4 ortho Protein Rprd1b, Regulation of nuclear pre-mRNA domain containing 1B Nploc4 ortho G G G G G G G G Pde12 Nploc4 ortho Slc38a6 Nploc4 ortho G G Raf1 Nploc4 ortho G G G G G G G G Yod1 Nploc4 ortho Pdlim5 Nploc4 ortho G G Svip Nploc4 ortho G G G G G G G Ssb Nploc4 ortho G G G G G G G G Cdc25a Nploc4 ortho G G G G Ndufs3_predicted Nploc4 ortho G G G G G G G G LOC312299 Nploc4 ortho G Meis1 protein, Protein Meis1 Nploc4 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9ES53 Q9ES54 - 10811609 - X 2 Q9ES53 Q9ES54 - 10811609 - X 2 P46462 Q9ES54 affinity chromatography technology 10811609 physical association X 2 P46462 Q9ES54 affinity chromatography technology 10811609 physical association X 2 P46462 Q9ES54 affinity chromatography technology 10811609 physical association X 2 P46462 Q9ES54 biochemical 10811609 colocalization X 2 P0CG48 Q9ES54 x-ray crystallography 15029239 association X 2 P70362 Q9ES54 biochemical 22232657 association X 2 P70362 Q9ES54 x-ray crystallography 22232657 association X 2 Q9ES54 Q4KMA2 affinity chromatography technology 19182904 physical association X 2 Q9ES53 Q9ES54 affinity chromatography technology 10811609 physical association X 2 Q9ES53 Q9ES54 affinity chromatography technology 10811609 physical association X 2 Q9ES54 O35987 affinity chromatography technology 10811609 physical association X 2 Q01853 Q9ES54 biochemical 22232657 association X 2 Q01853 Q9ES54 x-ray crystallography 22232657 association X 2 Q9ES54 pull down 11740563 association C 3 Q9ES54 affinity chromatography technology 10811609 association C 3 Q9ES54 anti bait coimmunoprecipitation 16103111 association C 4 Q9ES53 Q9ES54 affinity chromatography technology 10811609 association X 2 Q9ES54 transmission electron microscopy 17202270 physical association C 4 Q9ES54 electron tomography 22232657 physical association C 3 Q9ES54 transmission electron microscopy 17202270 physical association C 3 Q9ES54 pull down 22232657 physical association C 3 Q9ES54 transmission electron microscopy 22232657 physical association C 3 Q9ES54 molecular sieving 22232657 physical association C 3 Q9ES54 molecular sieving 17202270 physical association C 3 P70362 Q9ES54 molecular sieving 17202270 direct interaction X 2 P70362 Q9ES54 molecular sieving 22232657 direct interaction X 2 P70362 Q9ES54 electron tomography 17202270 direct interaction X 2 P70362 Q9ES54 mass spectrometry studies of complexes 17202270 direct interaction X 2 P70362 Q9ES54 transmission electron microscopy 22232657 direct interaction X 2 P70362 Q9ES54 pull down 22232657 direct interaction X 2 P70362 Q9ES54 transmission electron microscopy 17202270 direct interaction X 2 Q9ES54 anti tag coimmunoprecipitation 18775313 association C 5 Q9ES54 anti tag coimmunoprecipitation 18775313 association C 4 P0CG48 Q9ES54 nuclear magnetic resonance 12644454 direct interaction X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9ES54 O35987 NPLOC4 NSFL1C 0.21 10811609 Q9ES54 P0CG50 NPLOC4 UBC 0.309 12411482 Q9ES54 P70362 NPLOC4 UFD1L 0.454 22232657 Q9ES54 Q01853 NPLOC4 VCP 0.454 22232657 Q9ES54 Q9ES53 NPLOC4 UFD1L 0.376 10811609 Q9ES54 P0CG48 NPLOC4 UBC 0.523 12644454,15029239 Q9ES54 P46462 NPLOC4 VCP 0.454 10811609 Q9ES54 P55072 NPLOC4 VCP 0.126 18775313 Q9ES54 Q8TAT6 NPLOC4 NPLOC4 0.126 18775313 Q9ES54 Q92890 NPLOC4 UFD1L 0.126 18775313 Q9ES54 Q96JH7 NPLOC4 VCPIP1 0.126 18775313 Q9Y263 Q9ES54 PLAA NPLOC4 0.126 18775313 Q9ES54 Q4KMA2 NPLOC4 RAD23B 0.21 19182904