PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Gbeta76C Mannose-6-phosphate isomerase 14605208 biogrid,i2d,mint,intact exp G G G Gbeta76C Ggamma30A 10608815,15205461 biogrid,i2d,intact exp G G G Gbeta76C wupA 14605208 biogrid,i2d,mint,intact exp G G G Gbeta76C Fas2 25294943 intact exp G G G Gbeta76C CG17134, RE02351p 14605208 biogrid,i2d,mint,intact exp MTA1-like Gbeta76C 25294943 intact exp G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VH77 P29829 - 14605208 - X 2 P36188 P29829 - 14605208 - X 2 Q9VKP6 P29829 - 14605208 - X 2 P29829 E1JHC3 - 10608815 - X 2 Q9VH77 P29829 two hybrid 14605208 direct interaction X 2 P29829 M9NH88 two hybrid 14605208 direct interaction X 2 Q9VKP6 P29829 two hybrid 14605208 direct interaction X 2 P29829 E1JHC3 pull down 10608815 direct interaction X 2 Q9VH77 P29829 two hybrid 14605208 physical association X 2 P36188 P29829 two hybrid 14605208 physical association X 2 Q9VKP6 P29829 two hybrid 14605208 physical association X 2 Q9VH77 P29829 two hybrid 14605208 physical association X 2 E4NKM1 P29829 two hybrid 14605208 physical association X 2 Q9VKP6 P29829 two hybrid 14605208 physical association X 2 P29829 E1JHC3 anti tag coimmunoprecipitation 15205461 physical association X 2 P29829 E1JHC3 anti tag coimmunoprecipitation 15205461 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Gbeta76C Ggamma30A MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 10608815,15205461 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_60919|UniProt_39172|UniProt_39173 bait|prey|prey prey|bait|bait Gbeta76C wupA MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0471(mint)|MI:0465(dip)|(biogrid) UniProt_63302|MINT_19135|DIP_25392|BIOGRID_33741 prey|prey|-|prey null|null|-|bait Gbeta76C CG17134 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0465(dip)|(intact)|MI:0471(mint) BIOGRID_32197|DIP_17471|UniProt_61428|MINT_9727 prey|-|prey|prey bait|-|bait|bait Gbeta76C CG8417 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(biogrid)|(intact)|MI:0471(mint) DIP_25927|BIOGRID_47692|UniProt_53181|MINT_17577 -|prey|prey|prey -|bait|bait|bait