PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus cort Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p 24019759 biogrid,dip exp G sfl Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p 14605208 i2d,mint,intact exp G G G G G Fat-spondin, GH05860p Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p 25294943 intact exp G G G G G G PAPLA1 Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p 25294943 intact exp G G G G G G G G G La Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G Nrg Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p 25294943 intact exp G G G G G G G G G Mer Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p 15710747 biogrid,i2d,intact exp G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G cdc16 Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G Cks30A Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G Bub3-RA Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G dod Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p CG9198-PA, isoform A ortho G G G Bruce Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G Sirt6 Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G PCNA Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G Su(H) Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p mib1 ortho G G G G G G G G G Dreadlocks, isoform B, Dreadlocks, isoform C, Dreadlocks, isoform D, LD42588p Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p APC4-RA ortho G G G PPP5 Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G TER94 Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p drev1 ortho G G G G G fzy-RA Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G IP16020p, Phosphatase PTEN, Pten, isoform B, Pten, isoform D, Pten, isoform G, Pten, isoform H Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G CG2091, GH04919p Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p Ubiquitin-conjugating enzyme E2 S ortho G G G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p Imaginal discs arrested ortho G G CycB Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G APC10 Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G N Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G Medea Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p Anaphase-promoting complex subunit 2, LD21042p, Morula ortho G G G G G G G G G Mad2, RE72064p Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p Cell division cycle 5 ortholog, isoform A, Cell division cycle 5 ortholog, isoform B, LD21614p ortho G G G G G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p Apc7 ortho G Etl1 Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G Fmr1 Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G CG9636, isoform C, LD29354p Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G Ras85D Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G AT07979p2, Lemming B, isoform A, Lemming B, isoform B, Lemming B, isoform C, Lemming B, isoform D Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho Taf5 Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p CG3000-PA, isoform A, GH07620p, RE20929p, Retina aberrant in pattern, isoform B ortho G G G G G G G G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p RpL5 ortho G G G G G G G G G RnrS Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G CycA Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G Bx42 Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G arm Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G Sirt2 Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G FI09619p, Mad1, TXBP181-like protein Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G emb Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G drk Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p ortho G G G G G G G G G Cell division cycle 27 ortholog, isoform A, Cell division cycle 27 ortholog, isoform B, LD12661p CG32238, IP12417p ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VS37 E1JID8 - 14605208 - X 2 Q9VS37 M9ZVK8 - 14605208 - X 2 Q9VS37 Q24564 - 15710747 - X 2 Q9VS37 M9ZVK8 two hybrid 14605208 direct interaction X 2 Q9VS37 Q960N3 affinity chromatography technology 24019759 physical association X 2 Q9VS37 Q24564 two hybrid 15710747 direct interaction X 2 Q9VS37 anti tag coimmunoprecipitation 24019759 - C 5 Q9VS37 M9ZVK8 two hybrid 14605208 physical association X 2 Q9VS37 E1JID8 two hybrid 14605208 physical association X 2 Q9VS37 anti tag coimmunoprecipitation 24019759 - C 6 Q9VS37 Q960N3 anti tag coimmunoprecipitation 24019759 physical association X 2 Q9VS37 Q960N3 anti tag coimmunoprecipitation 24019759 physical association X 2 Q9VS37 Q24564 two hybrid 15710747 physical association X 2 Q9VS37 anti tag coimmunoprecipitation 25294943 association C 43 Q9VS37 M9ZVK8 two hybrid 14605208 physical association X 2 Q9VS37 E1JID8 two hybrid 14605208 physical association X 2 Q9VS37 Q24564 two hybrid fragment pooling approach 15710747 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VS37 Q7KN04 CDC27 FAT-SPONDIN 0.126 25294943 Q9VS37 Q24564 CDC27 MER 0.155 15710747 Q9VS37 P20241 CDC27 NRG 0.236 25294943 Q9VS37 Q9V3L1 CDC27 SFL 0.183 14605208 Q9VS37 P40796 CDC27 LA 0.21 14605208 Q9VS37 Q9VLS7 CDC27 Q9VLS7 0.126 25294943