PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus l(2)dtl Invadolysin 14605208 biogrid,i2d,mint,intact exp l(2)dtl pic 22036573 biogrid exp G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q24371 Q9VH19 - 14605208 - X 2 Q24371 Q9VH19 two hybrid 14605208 direct interaction X 2 Q24371 Q9XYZ5 affinity chromatography technology 22036573 physical association X 2 Q24371 Q9VH19 two hybrid 14605208 physical association X 2 Q24371 Q9VH19 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B l(2)dtl Invadolysin MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0465(dip)|(biogrid)|MI:0471(mint) UniProt_54988|DIP_8904|BIOGRID_36385|MINT_24153 prey|-|bait|prey bait|-|prey|bait l(2)dtl pic MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_67197 bait prey