PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus slbo Ubp64E unassigned4 intact exp Ubp64E CG7484, CG7484 protein, CG7484-PA, SD16138p 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G G Ubp64E Kokopelli, isoform B, Kokopelli, isoform C, Kokopelli, isoform D, Kokopelli, isoform E, RE65629p i2d exp koko Ubp64E 14605208 biogrid exp Ubp64E BcDNA.GH02435 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G G Doa Ubp64E 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G G Ubp64E KATNA1 14605208 biogrid,i2d,mint,intact exp G G G G Ubp64E CG7683 14605208 i2d,mint,intact exp Ubp64E CG11700-PA 14605208 biogrid,intact exp Ubp64E emb ortho G G G G G G G G G G Ubp64E CG8209, GM09977p ortho G G G G G G G G G G Ubp64E CG1486, isoform A, CG1486, isoform B, GH01474p ortho G G G G G G G G G Ubp64E aurA ortho G G Ubp64E Sirt7 ortho G G G G G Gprk2 Ubp64E ortho G G G G G G G G Ubp64E VhaSFD ortho G G G G G G G G G G 14-3-3epsilon Ubp64E ortho G G G G G G G G G G slmb Ubp64E ortho G G G G G G G G G Ubp64E 26S proteasome non-ATPase regulatory subunit 5 ortho G G G G G G G G G G Ubp64E Mannose-1-phosphate guanyltransferase beta ortho G G G G G G G G G G HDAC6, isoform G Ubp64E ortho G G G G G G G G G G Su(H) Ubp64E ortho G G G G G G G Ubp64E Ubiquitin-related modifier 1 homolog ortho G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q24574 - 14605208 - X 2 Q24574 R9PY16 - 14605208 - X 2 Q24574 Q9VVJ7 - 14605208 - X 2 Q9VN89 Q24574 - 14605208 - X 2 Q24574 - 14605208 - X 2 Q24574 Q9Y165 - 14605208 - X 2 Q24574 R9PY16 two hybrid 14605208 physical association X 2 Q24574 two hybrid 14605208 physical association X 2 Q24574 Q9VVJ7 two hybrid 14605208 physical association X 2 Q9VN89 Q24574 two hybrid 14605208 physical association X 2 Q961G6 Q24574 two hybrid 14605208 physical association X 2 Q24574 Q9Y165 two hybrid 14605208 physical association X 2 Q24574 R9PY16 two hybrid 14605208 physical association X 2 Q24574 A4V3J9 two hybrid 14605208 physical association X 2 Q24574 Q9VVJ7 two hybrid 14605208 physical association X 2 Q24574 Q02637 experimental interaction detection - physical association X 2 Q9VN89 Q24574 two hybrid 14605208 physical association X 2 Q961G6 Q24574 two hybrid 14605208 physical association X 2 Q24574 Q9Y165 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B slbo Ubp64E MI:0045(experimental interaction detection) pubmed:unassigned4 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_46059 unspecified role unspecified role Ubp64E morgue MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|(intact)|MI:0471(mint)|(biogrid) DIP_16175|UniProt_60127|MINT_8479|BIOGRID_41032 -|prey|prey|prey -|bait|bait|bait Doa Ubp64E MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(biogrid)|(intact)|MI:0471(mint) DIP_16930|BIOGRID_32079|UniProt_60890|MINT_18491 -|bait|null|null -|prey|bait|bait Ubp64E CG11700 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_64042 prey bait Ubp64E koko MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_32826 prey bait Ubp64E Kat60 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|MI:0471(mint)|MI:0465(dip) UniProt_58137|BIOGRID_34336|MINT_30503|DIP_6067 prey|prey|prey|- bait|bait|bait|- Ubp64E Q9W417 MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:0() MI:0915(physical association) MI:0471(mint) MINT_25154 prey bait Ubp64E CG7484 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0465(dip)|MI:0471(mint)|(intact) BIOGRID_33503|DIP_24414|MINT_16127|UniProt_62304 bait|-|bait|bait prey|-|prey|prey Ubp64E Bache_1796 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:693979() MI:0915(physical association) MI:0465(dip) DIP_9987 - - Ubp64E koko MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0465(dip) UniProt_26633|MINT_12821|DIP_20917 bait|bait|- prey|prey|-

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q961G6 Q24574 CG7683 UBP64E 0.21 14605208 Q24574 P49762 UBP64E DOA 0.332 14605208 Q9VVJ7 Q24574 Q9VVJ7 UBP64E 0.183 14605208 Q24574 Q02637 UBP64E SLBO 0.126 unassigned4 Q9VN89 Q24574 KAT60 UBP64E 0.183 14605208 Q9Y165 Q24574 MORGUE UBP64E 0.183 14605208 R9PY16 Q24574 R9PY16 UBP64E 0.183 14605208