PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C FI17352p1, Varicose, isoform B 14605208 biogrid,intact exp G G G G G G G G Fer1HCH-RD HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C 14605208 biogrid,intact exp G G G G G G G G G HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C cup 14605208 biogrid,intact exp HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C CG13458, GH20023p 14605208 biogrid,intact exp G G spn-A HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C 15710747 biogrid,intact exp G G G G G G HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C C15, FI01111p 14605208 biogrid exp HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C mRpL54-RA 14605208 biogrid,intact exp G G G G G G G G G HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C CG10979, isoform A, CG10979, isoform B, LD10772p 14605208 biogrid,intact exp G G G G G C15 HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C 14605208 intact exp HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C Cuticular protein 64Ad, RE69226p 14605208 biogrid,intact exp HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C cher 14605208 biogrid,intact exp G G G G G G G HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C CRAT 14605208 biogrid,intact exp G G G G G G G G G 14-3-3epsilon HL07962p, Transport and golgi organization 10, isoform A, Transport and golgi organization 10, isoform B, Transport and golgi organization 10, isoform C ortho G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VUL2 Q7K187 - 14605208 - X 2 Q9VYH1 Q7K187 - 14605208 - X 2 Q7K187 - 14605208 - X 2 Q7K187 Q2PDR9 - 14605208 - X 2 Q9VI16 Q7K187 - 14605208 - X 2 C6SV45 Q7K187 - 15710747 - X 2 Q7K187 - 14605208 - X 2 Q9VNI5 Q7K187 - 14605208 - X 2 Q7K187 Q9W2M8 - 14605208 - X 2 Q9VUL2 Q7K187 two hybrid 14605208 direct interaction X 2 Q9VYH1 Q7K187 two hybrid 14605208 direct interaction X 2 Q7K187 Q9VMA3 two hybrid 14605208 direct interaction X 2 Q7K187 Q9VEN1-2 two hybrid 14605208 direct interaction X 2 Q7K187 two hybrid 14605208 direct interaction X 2 Q7K187 Q2PDR9 two hybrid 14605208 direct interaction X 2 C6SV45 Q7K187 two hybrid 15710747 direct interaction X 2 Q9VNI5 Q7K187 two hybrid 14605208 direct interaction X 2 Q7K187 Q9VZF9 two hybrid 14605208 direct interaction X 2 Q7K187 Q0KIA8 two hybrid 14605208 direct interaction X 2 Q7K187 Q9W2M8 two hybrid 14605208 direct interaction X 2 Q7K187 two hybrid 14605208 physical association X 2 Q9VUL2 Q7K187 two hybrid 14605208 physical association X 2 Q9VYH1 Q7K187 two hybrid 14605208 physical association X 2 Q7K187 Q9VMA3 two hybrid 14605208 physical association X 2 Q7K187 two hybrid 14605208 physical association X 2 Q9VI16 Q7K187 two hybrid 14605208 physical association X 2 C6SV45 Q7K187 two hybrid 15710747 physical association X 2 Q9VNI5 Q7K187 two hybrid 14605208 physical association X 2 Q7K187 Q9VZF9 two hybrid 14605208 physical association X 2 Q7K187 Q9W2M8 two hybrid 14605208 physical association X 2 Q7K187 two hybrid 14605208 physical association X 2 Q9VIJ4 Q7K187 two hybrid 14605208 physical association X 2 Q9VUL2 Q7K187 two hybrid 14605208 physical association X 2 Q9VYH1 Q7K187 two hybrid 14605208 physical association X 2 Q7K187 Q9VMA3 two hybrid 14605208 physical association X 2 Q9VI16 Q7K187 two hybrid 14605208 physical association X 2 C6SV45 Q7K187 two hybrid fragment pooling approach 15710747 physical association X 2 Q9VEN1 Q7K187 two hybrid 14605208 physical association X 2 Q9VNI5 Q7K187 two hybrid 14605208 physical association X 2 Q9VD99 Q7K187 two hybrid 14605208 physical association X 2 Q7K187 Q9VZF9 two hybrid 14605208 physical association X 2 Q7K187 Q9W2M8 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Tango10 cher MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_42777 bait prey spn-A Tango10 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0399(two hybrid fragment pooling approach) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|(biogrid)|(intact) DIP_27321|BIOGRID_62797|UniProt_42337 -|bait|bait -|prey|prey Tango10 CG1041 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_58782 bait prey Tango10 vari MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_42780|UniProt_56713 bait|bait prey|prey Tango10 cup MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0465(dip) BIOGRID_36120|UniProt_54612|DIP_8529 prey|bait|- bait|prey|- Tango10 C15 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_56712 bait prey Tango10 cher MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(intact) DIP_18783|UniProt_56710 -|bait -|prey vari Tango10 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0465(dip) DIP_18786 - - Tango10 Cpr64Ad MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|MI:0465(dip) UniProt_50861|BIOGRID_38003|DIP_11536 prey|prey|- bait|bait|- Tango10 Fer3HCH MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|(intact)|(biogrid) DIP_18784|UniProt_56711|BIOGRID_42778 -|bait|bait -|prey|prey Tango10 CG13458 MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0465(dip) UniProt_52398|DIP_13081 bait|- prey|- Tango10 mRpL54 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0465(dip)|(intact) BIOGRID_42781|DIP_18787|UniProt_56714 bait|-|bait prey|-|prey Tango10 CG10979 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0465(dip)|(intact) BIOGRID_35628|DIP_7910|UniProt_53984 prey|-|bait bait|-|prey Tango10 C15 MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|(biogrid) DIP_18785|BIOGRID_42779 -|bait -|prey CG1041 Tango10 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_29915 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VZF9 Q7K187 CPR64AD TANGO10 0.183 14605208 Q9VMA3 Q7K187 CUP TANGO10 0.21 14605208 Q7K187 Q27297 TANGO10 SPN-A 0.155 15710747 Q9VD99 Q7K187 C15 TANGO10 0.183 14605208 Q9VEN1 Q7K187 CHER TANGO10 0.183 14605208 Q9VI16 Q7K187 Q9VI16 TANGO10 0.183 14605208 Q9VIJ4 Q7K187 VARI TANGO10 0.183 14605208 Q9VNI5 Q7K187 Q9VNI5 TANGO10 0.183 14605208 Q9VUL2 Q7K187 Q9VUL2 TANGO10 0.183 14605208 Q9VYH1 Q7K187 FER3HCH TANGO10 0.183 14605208 Q9W2M8 Q7K187 MRPL54 TANGO10 0.183 14605208