PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus nup44A CG7979, LD39959p 22036573 biogrid exp G G G G G G G G G G nup44A Mannose-6-phosphate isomerase 14605208 biogrid,intact exp G G G G G G G G G G nup44A UPF0586 protein CG11596 22036573 biogrid exp G G G G G G G G G G nup44A LD40846p, Ssu72 ortholog, isoform A, Ssu72 ortholog, isoform C 22036573 biogrid exp G G G G G G nup44A mio 22036573 biogrid exp, ortho G G G G G G G G G G nup44A BcDNA.LD18761, Nucleoporin 107kD ortho G G G G G G G G G G nup44A GM12270p, T-complex chaperonin 5, isoform A ortho G G G G G G G G G G nup44A GH01087p, Nucleoporin 93kD-2 ortho G G G Nup98-RA nup44A ortho G G G G G G G G PyK nup44A ortho G G G G G G G G G G nup44A T-complex protein 1 subunit delta ortho G G G G G G G G G G nup44A Atg6 ortho G G G G G G G G G G Cctgamma nup44A ortho G G G G G G G G G G beta'Cop nup44A ortho G G G G G G G G G G Fs(2)Ket nup44A ortho G G G G G G G G G G Ahcy13 nup44A ortho G G G G G G G G G G nup44A Rae1 ortho G G G G G G G G G G nup44A Nucleoporin 43kD ortho G G G G G G G G nup44A CG6089 ortho G G G G G G G G G G nup44A LP09464p, Nucleoporin 133kD ortho G G G G G G G nup44A Cystathionine beta-synthase ortho G G G G G G G G G nup44A Nup205 ortho G G G G G G G nup44A WD repeat-containing protein 59 homolog ortho G G G G G G G G G nup44A sbr ortho G G G G G G G G G G V-type proton ATPase subunit a nup44A ortho G G G G G G G G G G nup44A Nprl2 ortho G G G G G G G G nup44A CSN5 ortho G G G G G G G G G G nup44A Ndc1 ortho G G G G G G G G G nup44A CG3590-RA ortho G G G G G G G nup44A Nup160 ortho nup44A CG16892-RA ortho G G G G Dmn nup44A ortho G G G G G G G G G G nup44A nup44A ortho G G G G G G G G G G nup44A mbo ortho G G nup44A Nucleoporin NUP53 ortho G G G G G G G G G G Nurf-38 nup44A ortho G G G G G G G G G G nup44A LD47396p, Tcp-1eta ortho G G G G G G G G G G Cyp1 nup44A ortho G G G G G G G G G G nup44A Rep ortho G G G G G G G G G nup44A Serine hydroxymethyltransferase ortho G G G G G G G G G G nup44A CG7609, isoform B ortho G G G G G G G G Bx42 nup44A ortho G G G G G G G G G G nup44A Cell division cycle 5 ortholog, isoform A, Cell division cycle 5 ortholog, isoform B, LD21614p ortho G G G G G G G r nup44A ortho G G nup44A Nucleoporin 37kD, isoform A, Nucleoporin 37kD, isoform B, SD22926p ortho G G G G nup44A mAc ortho G G G G G G G G G G gp210 nup44A ortho G G G G G G G G CG12042, LD13436p nup44A ortho G G G G G G G G G nup44A sec13 ortho G G G G G G G G G G Nucleoporin 75kD, Nup75 nup44A ortho G G G G G G G G G nup44A Nucleoporin 154kD, isoform A, Nucleoporin 154kD, isoform C, Nucleoporin 154kD, isoform D, Nup154 ortho G G G G G G G G G G RpA-70 nup44A ortho G G G G G G G G G G nup44A CG9273 protein, CG9273-PA, GM04951p, Replication protein A2, isoform A, Replication protein A2, isoform B ortho G G G nup44A CG3018-PA, isoform A, Dorsal interacting protein 4, GM08377p, Lesswright, isoform A, Lesswright, isoform C, Lesswright, isoform D, RE25737p, Ubiquitin-conjugating enzyme, Ubiquitin-conjugating enzyme 9, Ubiquitin-conjugating enzyme 9 homolog ortho G G G G G G G G G G nup44A l(3)72Ab ortho G G G G G G G G G G RpII215 nup44A ortho G G G G G G G G G G nup44A Probable ATP-dependent RNA helicase DDX55 homolog, DEAD box protein 55 ortho G l(2)efl nup44A ortho G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q7K2X8 Q9VH77 - 14605208 - X 2 Q7K2X8 Q9VH77 two hybrid 14605208 direct interaction X 2 Q7K2X8 M9PGG7 affinity chromatography technology 22036573 physical association X 2 Q7K2X8 Q9VWE4 affinity chromatography technology 22036573 physical association X 2 Q9VQ89 Q7K2X8 affinity chromatography technology 22036573 physical association X 2 Q7K2X8 Q9VSE8 affinity chromatography technology 22036573 physical association X 2 Q7K2X8 Q9VH77 two hybrid 14605208 physical association X 2 Q7K2X8 Q9VH77 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Nup44A CG8417 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0465(dip)|(intact) BIOGRID_33875|DIP_25926|UniProt_53180 prey|-|prey bait|-|bait Nup44A CG11596 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_69030 prey bait Nup44A CG7979 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_70287 bait prey Nup44A Ssu72 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_72243 prey bait Nup44A mio MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_74986 prey bait