PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus arm Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p 17954973 biogrid exp G G G G G G G G G G Fas2 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p 21447707,25294943 biogrid,intact exp G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p LD42296p 14605208 intact exp NetB Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p 25294943 intact exp G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG31855, isoform B, CG31855-PA, RE70574p 22036573 biogrid exp G G G G G G G G G G SkpA Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p 19079254 intact exp G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG9083 14605208 biogrid exp Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Roc1a 18698375 biogrid exp, ortho G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Defective in cullin neddylation protein 14605208 biogrid,intact exp, ortho G G G G G G G G G G CycE Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p 16322693 biogrid exp, ortho G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Pros-alpha-6T ortho G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p WD repeat-containing protein 82 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p mahj ortho G G G G G G G G G RpS3 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho PCNA Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p DCN1-like protein ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p RpS16 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG9485, isoform B ortho G G G G G G G G G MTA1-like Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG16717 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p RE62581p, RH06526p, Ribosomal protein L21, isoform A, Ribosomal protein L21, isoform B, Ribosomal protein L21, isoform C ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p wds ortho G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p 40S ribosomal protein S24 ortho Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p bel ortho G G G G G G G G G G EF2 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G betaTub56D Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Rox8-RD ortho G G G G G G G G G G scu Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Eno Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Elongation factor Tu Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G RpL14 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p tRNA-splicing ligase RtcB homolog ortho G G G G G G G G G G RpS18 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CSN5 ortho G G G G G G G G G G snf Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G His4, His4r, His4:CG31611, His4:CG33869, His4:CG33871, His4:CG33873, His4:CG33875, His4:CG33877, His4:CG33879, His4:CG33881, His4:CG33883, His4:CG33885, His4:CG33887, His4:CG33889, His4:CG33891, His4:CG33893, His4:CG33895, His4:CG33897, His4:CG33899, His4:CG33901, His4:CG33903, His4:CG33905, His4:CG33907, His4:CG33909 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho WD repeat-containing protein 48 homolog Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Cullin 3, isoform F, FI19425p1 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Usp7 ortho G G G G G G G G G G IGF-II mRNA-binding protein, isoform L, IGF-II mRNA-binding protein, isoform M Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p SmG ortho G G G G G G G G G G RpL11 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Fs(2)Ket Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CSN1b ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p RpL35-RB ortho G G G G G G G G G G Hsc70-3 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Interleukin enhancer-binding factor 2 homolog ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p RE17737p, RH44960p, Ribosomal protein L35A ortho G G G G G G G G G G RpS25 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p AT19436p, Ribonuclease H1, isoform A ortho G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG14325 ortho Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CSN8 ortho G G G G G G G G G G pAbp Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG10077, isoform D, CG10077-PA, isoform A, GH10652p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Rpd3 ortho G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Transmembrane protein 43 homolog ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Retinoblastoma-binding protein 5 homolog ortho G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Hsc70-1 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG7477 ortho G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Sirt7 ortho G G G G G Ahcy13 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G RpL27A Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G CG33995-RB Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho La Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG5203-PA, Carboxy terminus of Hsp70-interacting protein, RE01069p ortho G G G G G G G G G G RpL9 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p RpS7 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p RpL24 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CSN4 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p IP16020p, Phosphatase PTEN, Pten, isoform B, Pten, isoform D, Pten, isoform G, Pten, isoform H ortho G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Nap1-RA ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Rat1 ortho G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Cullin 5, FI20194p1 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Roc2-RA ortho G G G G G G G G G G SmD3 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Pcd Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Dlc90F ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG10652-PA, isoform A, RE25263p, Ribosomal protein L30, isoform B, Ribosomal protein L30, isoform E ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG6459 protein, CG6459-PA, LD29590p, P32 ortho G G G G G G G G G G Sin3A Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Ddx1 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p isoQC ortho G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG6950-RC ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p LD41216p, SMU1 ortholog, isoform A, SMU1 ortholog, isoform B, SMU1 ortholog, isoform C ortho G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG10343-PA, GM16226p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p csul ortho G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG3909 ortho G G G G G G G G G G RpL7 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Raptor, isoform B, Raptor, isoform C ortho Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p WD repeat-containing protein 26 homolog ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p SmD2 ortho G G G G G G G G G G Zizimin ortholog, isoform K Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG2118, isoform A, CG2118, isoform C, GM14617p ortho G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p hlc ortho G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Lethal (2) 09851, isoform A, Lethal (2) 09851, isoform B, RE17371p, RE55020p ortho G G G G G G G G G G RpS2 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG3436, isoform A, CG3436, isoform C, GM13767p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Myosin heavy chain-like, isoform B ortho G G G G CG1440-RC Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G RpL15 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p AnxB11 ortho G G G G G G G G G G Cdc37 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G RpL4 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Nedd8 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p SmD1 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p hiw ortho G G G G G E(z) Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CSN3 ortho G G G G G G G G G G Caf1 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Ubi-p63E Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CSN7 ortho G G G G G G G G G G Gprk2 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p RE08669p, Ribosomal protein L6, isoform B ortho G G G G G G G G G G Ef1alpha100E Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G Pgam5 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G sina Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p sbr ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG14220-RA ortho G G G G G RpS20 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Hsc70-5 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G RpLP0 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G RpS6 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG14894, isoform A, CG14894, isoform B, LP07287p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p p28/SF2 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p RE28824p, Ribosomal protein L12, isoform A, Ribosomal protein L12, isoform B, Ribosomal protein L12, isoform C ortho G G G G G G G G G G Ribonuclease P protein subunit p20, RNaseP protein p20 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho mle Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Su(z)12 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p 60S ribosomal protein L27 ortho G G G G G G G G G G Sod Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Pen Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G RpL13 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p AT18160p, CG9945, isoform A, CG9945, isoform B ortho G G G G G RpL3 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Cand1 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Conserved oligomeric Golgi complex subunit 4, COG complex subunit 4 ortho G G G G G G G G G G His2Av Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CTPsyn ortho G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p pic ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Dhx15 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Cyclin G, isoform A, Cyclin G, isoform B, Cyclin G, isoform C, Cyclin G, isoform D, Cyclin G, isoform F, LD46284p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p RpL8 ortho G G G G G G G G G G gammaTub37C Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p RpS8 ortho G G G G G G G G G G RpS4 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Cullin 2, isoform A, Cullin 2, isoform B, LD36177p ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p RpL18 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CSN6 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Trx-2 ortho G G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p Peroxiredoxin 3, SD08737p, Thioredoxin peroxidase 3 ortho G G G G G G G G G G Hsp83 Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G G G G G G G G cdc2c Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p ortho G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p hoip ortho Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p CG4538-RA ortho G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q5BI50 Q8T8S1 - 14605208 - X 2 Q5BI50 M9NDQ2 affinity chromatography technology 16322693 physical association X 2 Q5BI50 M9NDQ2 affinity chromatography technology 16322693 physical association X 2 Q5BI50 two hybrid 14605208 direct interaction X 2 Q5BI50 Q9W5E1 affinity chromatography technology 18698375 physical association X 2 Q5BI50 Q8T8S1 two hybrid 14605208 direct interaction X 2 P18824-2 Q5BI50 affinity chromatography technology 17954973 physical association X 2 Q8IP73 Q5BI50 affinity chromatography technology 22036573 physical association X 2 Q5BI50 two hybrid 14605208 physical association X 2 Q5BI50 Q8T8S1 two hybrid 14605208 physical association X 2 Q5BI50 Q8T8S1 two hybrid 14605208 physical association X 2 Q5BI50 Q8SX59 two hybrid 14605208 physical association X 2 Q5BI50 O77430 two hybrid array 19079254 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B skpA Cul-4 MI:0397(two hybrid array) 19079254 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_43678 bait prey Cul-4 CG13322 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_52163 prey bait Cul-4 CG9083 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_53253 prey bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q5BI50 O77430 CUL4 SKPA 0.236 19079254 Q8SX59 Q5BI50 Q8SX59 CUL4 0.183 14605208 Q8T8S1 Q5BI50 Q8T8S1 CUL4 0.183 14605208 Q5BI50 P34082 CUL4 FAS2 0.236 25294943,21447707 Q5BI50 Q24568 CUL4 NETB 0.126 25294943