PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ciao1 MIP18 family protein CG30152 22036573 biogrid exp, ortho G G G G G G G G G G Ciao1 MIP18 family protein CG7949 19079254,14605208,22036573 biogrid,intact exp, ortho G G G G G G G G G G Ciao1 Putative elongator complex protein 4, ELP4 ortho G G G G G G G G G G Ciao1 ND-39 ortho G G G G G G G G G G RpS26 Ciao1 ortho G G G G G G G G G G gammaTub23C Ciao1 ortho G G G G G G G Acetyl-CoA carboxylase, isoform A Ciao1 ortho G G G G G G G G G G Ciao1 wds ortho G G G G G G G G l(2)tid Ciao1 ortho G G G G G G G G G G Ciao1 Elp2 ortho G G G G G G G G EG:BACR7A4.11 Ciao1 ortho G G G G G G Ciao1 Probable ATP-dependent RNA helicase DDX55 homolog, DEAD box protein 55 ortho G CG8950, isoform A, CG8950, isoform B, LD44919p Ciao1 ortho G G Ciao1 Antimeros, isoform A, Antimeros, isoform B, LD37523p ortho G G G G G G G G Ciao1 Hyrax, Hyrax, isoform A, Hyrax, isoform B, LD47989p ortho G G G G G G G G G G 14-3-3epsilon Ciao1 ortho G G G G G G G G G G Ciao1 CG2990-RB ortho G Ciao1 CG3756, LP03982p ortho G G G G G G G G G G CG2469, isoform A, CG2469, isoform B, LD24034p Ciao1 ortho G G G G G G G G G G SRPK Ciao1 ortho G G G G G G G G G Ciao1 Cytosolic Fe-S cluster assembly factor NUBP2 homolog ortho G G G G G G G G G G Ciao1 CG12050-RB ortho G G G G G G G G G Ciao1 CG5808 ortho G Ciao1 Cytoplasmic tRNA 2-thiolation protein 2 ortho G G G G G G G G G beta'Cop Ciao1 ortho G G G G G G G G G G DNApol-alpha180 Ciao1 ortho G DNApol-delta Ciao1 ortho G G G G Ciao1 Ciao1 ortho G G G G G G G G G G Ciao1 Formin-like protein CG32138 ortho G G G G G G G Ciao1 Gas8 ortho G Ciao1 GH01087p, Nucleoporin 93kD-2 ortho G G G Myo61F Ciao1 ortho G G G G G G Ciao1 Threonylcarbamoyladenosine tRNA methylthiotransferase ortho G G G G G G G G G Myosin 95E, isoform E Ciao1 ortho G G G G G G G G Ciao1 CG16717 ortho G G G G G G G G G G Ciao1 DNApol-alpha60 ortho G Ciao1 Pglym87 ortho G Ciao1 CG9485, isoform B ortho G G G G G G G G G Ciao1 Nucleoporin NUP53 ortho G G G G G G G G G G DNApol-alpha50 Ciao1 ortho G Inos Ciao1 ortho G G G G G G G G G G Ciao1 Dynein assembly factor 5, axonemal ortho G G Ciao1 Fib ortho G G G G G G G G G G Ciao1 DNApol-epsilon255 ortho G CG30349-RA Ciao1 ortho G G G G G G G G G G Ciao1 l(2)37Cd ortho G G G G Myo31DF Ciao1 ortho G G G G G G G G G G Ciao1 CG11652, isoform A, CG11652, isoform B, CG11652, isoform C, LD10878p ortho G G G G G G G G G G Ciao1 Xeroderma pigmentosum D ortholog ortho G G G sgl Ciao1 ortho G G G G G G G G G Ciao1 CG16928-PA, Endo/exonuclease Mre11 ortho G G G G G G G G G Ciao1 Probable cytosolic Fe-S cluster assembly factor CG17683 ortho G G G G G G G G G Ciao1 DNApol-alpha73 ortho G Ciao1 CG3909 ortho G G G G G G G G G G Ciao1 mRpL24 ortho G G G G G G G G G G Ciao1 Mcm3 ortho G Gl Ciao1 ortho G G G G G G G G G G Ciao1 Probable dolichol-phosphate mannosyltransferase, DPM synthase, Dolichol-phosphate mannose synthase ortho G G G G G G G G G G Ciao1 Elp3 ortho G G G G G G G G G G Ciao1 l(3)72Ab ortho G G G G G G G G G G wbl Ciao1 ortho G G Ciao1 Gigas, isoform A ortho G G G G G G G G G G Prosbeta6 Ciao1 ortho G G G G G G G G G G Rpn8 Ciao1 ortho G G G G G G G G G G Ciao1 Pixie, isoform A, Pixie, isoform B, RE71924p ortho G G G G G G G G G G Ciao1 Mcm5 ortho G RpS3 Ciao1 ortho Ciao1 Regulator of telomere elongation helicase 1 homolog ortho G G G G G Ciao1 CG3744, isoform D, CG3744, isoform G ortho G G G G G G G G stc Ciao1 ortho G G G G G G G G G G Ciao1 CG4538-RA ortho G G G G G G G G G G Hsp60 Ciao1 ortho G G G G G G G G G G Ciao1 TER94 ortho G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q7K1Y4 Q9VTC4 - 14605208 - X 2 Q7K1Y4 Q9VTC4 two hybrid 14605208 direct interaction X 2 Q7K1Y4 Q9VTC4 affinity chromatography technology 22036573 physical association X 2 Q7K1Y4 Q9V968 affinity chromatography technology 22036573 physical association X 2 Q7K1Y4 Q9VTC4 two hybrid 14605208 physical association X 2 Q7K1Y4 Q9VTC4 two hybrid 14605208 physical association X 2 Q7K1Y4 Q9VTC4 two hybrid array 19079254 physical association X 2 Q7K1Y4 Q9VTC4 two hybrid array 19079254 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Ciao1 CG7949 MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0397(two hybrid array)|MI:0018(two hybrid) 14605208,19079254,22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|(intact)|(biogrid)|(intact)|(intact)|(biogrid) DIP_11837|UniProt_43492|BIOGRID_70153|UniProt_51161|UniProt_43303|BIOGRID_31001 -|prey|bait|prey|bait|bait -|bait|prey|bait|prey|prey Ciao1 CG30152 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_65242 bait prey