PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CG4080, isoform A, CG4080, isoform B, LD02310p CG14232, isoform A, CG14232, isoform B, LD35087p 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G CG4080, isoform A, CG4080, isoform B, LD02310p CG34401, isoform A 14605208 biogrid exp G G G G G G G G G D CG4080, isoform A, CG4080, isoform B, LD02310p 14605208 intact exp G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VSX7 Q9VWD5 - 14605208 - X 2 Q9VSX7 Q9VWD5 two hybrid 14605208 direct interaction X 2 Q9VSX7 two hybrid 14605208 direct interaction X 2 Q9VSX7 Q9VWD5 two hybrid 14605208 physical association X 2 Q9VSX7 two hybrid 14605208 physical association X 2 Q9VSX7 Q9VWD5 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CG4080 CG14232 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|MI:0471(mint)|(intact)|(biogrid) DIP_14348|MINT_29261|UniProt_47664|BIOGRID_31513 -|prey|prey|prey -|bait|bait|bait CG4080 Q9VWN8 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:0() MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact) MINT_13596|UniProt_48926 prey|prey bait|bait CG4080 CG34401 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_61663 prey bait