PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ufd1-like CG6873-RA 14605208 biogrid,i2d,mint,intact exp G Mad2, RE72064p Ufd1-like 15575970 biogrid,i2d,mint,intact exp G G CG15124, IP07030p Ufd1-like 14605208 biogrid,intact exp G CG14606, isoform A, CG14606, isoform B, IP11886p Ufd1-like 14605208 biogrid,i2d,mint,intact exp G HBS1 Ufd1-like i2d exp LD03247p, Pomp Ufd1-like 22036573 biogrid exp G G G G G G G G G G Ufd1-like CG8128, isoform A, CG8128, isoform B, FI03680p 15575970 biogrid,i2d exp G G G G G G G G G G Ufd1-like HBS1-RA 14605208 i2d,mint,intact exp G G G G G G G G G G Ge-1 Ufd1-like 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G CG12321-RA Ufd1-like 22036573 biogrid exp G G G G G G G G G G GH03273p Ufd1-like 15575970 i2d,mint,intact exp TER94 Ufd1-like 23747190 biogrid exp, ortho G G G G G G G G G G Npl4 Ufd1-like 14605208,22036573 biogrid,i2d,mint,intact exp, ortho G G G G G G G G G G tRNA-splicing ligase RtcB homolog Ufd1-like ortho G G G G G G G G G G Itp-r83A Ufd1-like ortho G G G G G G G G G Caspar, isoform A, Caspar, isoform B, LD03368p Ufd1-like ortho G G G G G G G G G G Dhx15 Ufd1-like ortho G G G G G G G G G G Ufd1-like CG5290-RA ortho G G G G Su(z)12 Ufd1-like ortho G G G G G G G G G G Ufd1-like Rae1 ortho G G G G G G G G G G CG2720-PA, LD03220p Ufd1-like ortho G G G G G G G G G G LD22577p, Smt3 activating enzyme 2 Ufd1-like ortho G G G G G G G G G G Ubiquitin thioesterase OTU1 Ufd1-like ortho G G G G G G G G G G Smt3 Ufd1-like ortho G G G G G G G G G G Phospholipase A2 activator protein, isoform A, Phospholipase A2 activator protein, isoform B, Phospholipase A2 activator protein, isoform C, SD05646p Ufd1-like ortho G G G G G G G G G G Ufd1-like CG8184, isoform H ortho G G G G G G G G G G Rep Ufd1-like ortho G G G G G G G G G Ufd1-like Ufd1-like ortho G G G G G G G G G G Adenylyl cyclase-associated protein Ufd1-like ortho G G G G G G G G G G Ufd1-like As ortho G G G G G G G G G G E(z) Ufd1-like ortho G G G G G G G Ufd1-like LD21074p, Programmed cell death 4 ortholog, isoform A, Programmed cell death 4 ortholog, isoform B, Programmed cell death 4 ortholog, isoform C, Programmed cell death 4 ortholog, isoform D ortho G G G G G G G G G G hrg Ufd1-like ortho G G G G G G G G G G GH01724p, p47 Ufd1-like ortho G G G G G G G G G G slmb Ufd1-like ortho G G G G G G G G G Ufd1-like CG16721, isoform A, CG16721, isoform B, CG16721, isoform C, LD23868p ortho G G G G G G G G G G CG42306-RA Ufd1-like ortho cact Ufd1-like ortho G G G G G G G G G G Octbeta2R Ufd1-like ortho Ubi-p63E Ufd1-like ortho G G G G G G G G G G Ufd1-like Anaphase-promoting complex subunit 2, LD21042p, Morula ortho G G G G G G G G G G Ufd1-like Aats-gly-RB ortho G G G G G G G G G G CG9934, isoform A, CG9934, isoform B, LD24832p Ufd1-like ortho G G G G G G G G G G vps2 Ufd1-like ortho G G G G G G G G G G Ufd1-like 26S proteasome regulatory complex subunit p97, Regulatory particle non-ATPase 1 ortho G G G G G G G G G G rad23 Ufd1-like ortho G G G G G G G G G G ImpL3 Ufd1-like ortho G G G G G G Skp2, isoform A, Skp2, isoform E Ufd1-like ortho G G G G Rpn8 Ufd1-like ortho G G G G G G G G G G CG5886, GH01188p Ufd1-like ortho G G G G G G G G G G AT16033p, CG3473, isoform A, CG3473, isoform B Ufd1-like ortho G BcDNA.LD12153 Ufd1-like ortho G G G G G G G G G G Ufd1-like DCN1-like protein ortho G G G G G G G G G G CG8209, GM09977p Ufd1-like ortho G G G G G G G G G G Fas-associated factor, isoform A, Fas-associated factor, isoform B, GH16914p Ufd1-like ortho G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VKK1 Q9VTF9 - 14605208 - X 2 Q9VTF9 Q9VWR1 - 14605208 - X 2 Q9VI78 Q9VTF9 - 14605208 - X 2 Q9VTF9 - 14605208 - X 2 Q9W074 Q9VTF9 - 14605208 - X 2 Q9VRQ2 Q9VTF9 - 15575970 - X 2 Q9VXR9 Q9VTF9 - 15575970 - X 2 Q9VTF9 Q4V5L1 - 14605208 - X 2 Q9VKK1 Q9VTF9 two hybrid 14605208 direct interaction X 2 Q9VBP9-2 Q9VTF9 two hybrid 14605208 direct interaction X 2 Q9VBP9-2 Q9VTF9 affinity chromatography technology 22036573 physical association X 2 Q9VTF9 Q9VWR1 two hybrid 14605208 direct interaction X 2 Q9VIJ5 Q9VTF9 affinity chromatography technology 22036573 physical association X 2 Q9VI78 Q9VTF9 two hybrid 14605208 direct interaction X 2 Q9VEC2 Q9VTF9 affinity chromatography technology 22036573 physical association X 2 Q9VRQ2 Q9VTF9 two hybrid 15575970 direct interaction X 2 Q9VXR9 Q9VTF9 two hybrid 15575970 direct interaction X 2 Q9VTF9 Q7KN62-2 affinity chromatography technology 23747190 physical association X 2 Q9VTF9 Q4V5L1 two hybrid 14605208 direct interaction X 2 Q9VKK1 Q9VTF9 two hybrid 14605208 physical association X 2 Q9VTF9 Q9VWR1 two hybrid 14605208 physical association X 2 Q9VI78 Q9VTF9 two hybrid 14605208 physical association X 2 Q9W074 Q9VTF9 two hybrid 14605208 physical association X 2 Q9VBP9 Q9VTF9 two hybrid 14605208 physical association X 2 Q9VTF9 Q4V5L1 two hybrid 14605208 physical association X 2 Q9VKK1 Q9VTF9 two hybrid 14605208 physical association X 2 Q9VTF9 Q9VWR1 two hybrid 14605208 physical association X 2 Q9VI78 Q9VTF9 two hybrid 14605208 physical association X 2 Q961V9 Q9VTF9 two hybrid 15575970 physical association X 2 Q9W074 Q9VTF9 two hybrid 14605208 physical association X 2 Q9VBP9 Q9VTF9 two hybrid 14605208 physical association X 2 Q9VRQ2 Q9VTF9 two hybrid 15575970 physical association X 2 Q9VTF9 Q4V5L1 two hybrid 14605208 physical association X 2 Q9VTF9 Q4V5L1 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CG15124 Ufd1-like MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_31841|UniProt_59750|UniProt_59749 bait|bait|prey prey|prey|bait Q9V8X3 Ufd1-like MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 14605208 taxid:0() taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_8115|MINT_8114 bait|prey prey|bait CG14606 Ufd1-like MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(biogrid)|(intact) DIP_14864|MINT_29685|BIOGRID_31633|UniProt_48153 -|prey|bait|prey -|bait|prey|bait Pomp Ufd1-like MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_74675 bait prey Ge-1 Ufd1-like MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0465(dip)|(biogrid)|MI:0471(mint) UniProt_62740|DIP_24841|BIOGRID_46884|MINT_16507 prey|-|bait|prey bait|-|prey|bait HBS1 Ufd1-like MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(intact) DIP_19254|MINT_11310|UniProt_57113 -|bait|bait -|prey|prey CG12321-RA Ufd1-like MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_73615 prey bait Ufd1-like CG6873-RA MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(biogrid)|MI:0465(dip)|(intact) MINT_16532|BIOGRID_33632|DIP_24866|UniProt_62765 bait|bait|-|bait prey|prey|-|prey Ufd1-like CG8128 MI:0018(two hybrid) 15575970 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_58390 prey bait CG8128 Ufd1-like MI:0018(two hybrid)|MI:0018(two hybrid) 15575970 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_39751|MINT_21471 bait|bait prey|prey TER94 Ufd1-like MI:0004(affinity chromatography technology) 23747190 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_75640 prey bait CG4673 Ufd1-like MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208,22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(intact)|MI:0471(mint)|MI:0465(dip)|(biogrid) BIOGRID_68411|UniProt_50771|MINT_15336|DIP_23570|BIOGRID_33304 prey|prey|prey|-|bait bait|bait|bait|-|prey mad2 Ufd1-like MI:0018(two hybrid)|MI:0018(two hybrid) 15575970 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_39752|MINT_21470 bait|bait prey|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VTF9 Q9VBP9 UFD1-LIKE NPL4 0.436 14605208,22036573 Q9W074 Q9VTF9 HBS1 UFD1-LIKE 0.21 14605208 Q9VTF9 Q9VKK1 UFD1-LIKE GE-1 0.354 14605208 Q9VTF9 Q9VI78 UFD1-LIKE Q9VI78 0.21 14605208 Q9VTF9 Q7KN62 UFD1-LIKE TER94 0.21 23747190 Q9VTF9 Q961V9 UFD1-LIKE Q961V9 0.183 15575970 Q9VTF9 Q9VRQ2 UFD1-LIKE MAD2 0.183 15575970 Q9VWR1 Q9VTF9 CG6873-RA UFD1-LIKE 0.21 14605208 Q9VTF9 Q4V5L1 UFD1-LIKE Q4V5L1 0.354 14605208