PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RAD54 CG7656-RA 19079254 intact exp G G G dod CG7656-RA 22036573 biogrid exp G G G G CG8368, isoform B, CG8368-PA, isoform A, LD29573p CG7656-RA 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G G CG9511-PA, FI01864p CG7656-RA 14605208 biogrid,i2d,mint,intact exp G G G G G G spn-A CG7656-RA 19079254 intact exp G G G G G G G CG7656-RA star1 14605208 biogrid,i2d,mint,intact exp SkpA CG7656-RA 19079254 intact exp, ortho G G G G G G G G G G Ubc12 CG7656-RA 19079254 intact exp, ortho G G G G G G G G G G Prosbeta7 CG7656-RA ortho G G G G G G G G G G GH08526p, Suppressor of Stem-Loop mutation ortholog, isoform A, Suppressor of Stem-Loop mutation ortholog, isoform B CG7656-RA ortho G G G G G G G G G G CG7656-RA CG7033, SD02216p ortho G G G G G G G G G G RpII15 CG7656-RA ortho G G G G G G G G G G CG7656-RA Roc1a ortho G G G G G G G G G CG8258, LD24495p CG7656-RA ortho G G G G G G G G G G RpS27A CG7656-RA ortho G G G G G G G G G G CG7656-RA DNA-ligI ortho G Ubi-p63E CG7656-RA ortho G G G G G G G G G G CG7656-RA Ubc7 ortho G G G G G G G G G G CkIIalpha CG7656-RA ortho G G G G G G G G G G CG7656-RA Mfe2 ortho G G G G G G G G G G Cytosolic Fe-S cluster assembly factor NUBP2 homolog CG7656-RA ortho G G G G G G G G G G CG6796, RE15573p CG7656-RA ortho G G G G Fbw5, GH09073p CG7656-RA ortho G G G G G G G G G G CG7656-RA GH10889p, Protein interacting with APP tail-1, isoform A, Protein interacting with APP tail-1, isoform C ortho G G G G G G G G G G ari-2 CG7656-RA ortho G G G G G G G G G G CG7656-RA CG7974, isoform A, CG7974, isoform B, GM02612p ortho G G G G G CG7656-RA LD16419p, RhoGDI, isoform A, RhoGDI, isoform B ortho G G G G G G G G G G Prosalpha2 CG7656-RA ortho G G G G G G G G G G Nedd8 CG7656-RA ortho G G G G G G G G G G CG7656-RA l(1)G0022 ortho G G G G G G G G G G Hsp60 CG7656-RA ortho G G G G G G G G G G CG7656-RA BcDNA:GH03108 ortho G G G G G G G G G G CG7656-RA CG7656-RA ortho G G G G G G G G G G 14-3-3epsilon CG7656-RA ortho G G G G G G G G G G Rpb10 CG7656-RA ortho G G G G G G G G G G GH24511p, Ubiquitin activating enzyme 1, isoform A CG7656-RA ortho G G G G G G G G G G slmb CG7656-RA ortho G G G G G G G G G CG17544-RA CG7656-RA ortho G G G G G G G G G CG7656-RA CG17807 ortho G G G G G G G G G Prosbeta6 CG7656-RA ortho G G G G G G G G G G FI06027p, Tryptophanyl-tRNA synthetase CG7656-RA ortho G G G G AT06125p, CG6195 CG7656-RA ortho G G G G G G G G G G Hsc70-5 CG7656-RA ortho G G G G G G G G G G Probable ATP-dependent RNA helicase DDX55 homolog, DEAD box protein 55 CG7656-RA ortho G Mpcp-RA CG7656-RA ortho G G G G G G G G G G tam CG7656-RA ortho G G eff CG7656-RA ortho G G G G G G G G G G Tip60 CG7656-RA ortho G G G G G G G G G CG8026-RB CG7656-RA ortho G G G G G G G G G G CG15141, LD24839p CG7656-RA ortho G G G G G G G G G G RpL40 CG7656-RA ortho G G G G G G G G G G Arginine methyltransferase 1, CG6554 protein, CG6554-PA, LD28808p CG7656-RA ortho G G G G G G G G G G Pros-alpha-6T CG7656-RA ortho G CG7656-RA Upf1 ortho G G G G G G G G G G Pacman, isoform B CG7656-RA ortho G G G G G G G G G G Probable trans-2-enoyl-CoA reductase, mitochondrial CG7656-RA ortho G G G G G G G G G G Hsc70Cb, isoform G, Hsc70Cb, isoform H CG7656-RA ortho G G G G G G G G G G CG9003-RC CG7656-RA ortho G G G G G G G G G G CG4390, isoform B CG7656-RA ortho G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VUR4 P54353 affinity chromatography technology 22036573 physical association X 2 Q9VVQ1 Q9VUR4 two hybrid 14605208 direct interaction X 2 Q9VRX7 Q9VUR4 two hybrid 14605208 direct interaction X 2 Q9VUR4 Q9VME1 two hybrid 14605208 direct interaction X 2 Q9VVQ1 Q9VUR4 two hybrid 14605208 physical association X 2 Q9VRX7 Q9VUR4 two hybrid 14605208 physical association X 2 Q9VUR4 Q9VME1 two hybrid 14605208 physical association X 2 Q9VUR4 O76460 two hybrid array 19079254 physical association X 2 Q9VSF3 Q9VUR4 two hybrid array 19079254 physical association X 2 C6SV45 Q9VUR4 two hybrid array 19079254 physical association X 2 Q9VUR4 O77430 two hybrid array 19079254 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CG7375 CG7656-RA MI:0397(two hybrid array) 19079254 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_43291 bait prey dod CG7656-RA MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_70059 bait prey okr CG7656-RA MI:0397(two hybrid array) 19079254 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_43829 prey bait CG7656-RA star1 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_47336 prey bait CG8368 CG7656-RA MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_47463 prey bait skpA CG7656-RA MI:0397(two hybrid array) 19079254 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_43310 bait prey CG42369 CG7656-RA MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_47464 prey bait spn-A CG7656-RA MI:0397(two hybrid array) 19079254 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_43720 prey bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VUR4 O77430 CG7656-RA SKPA 0.126 19079254 Q9VUR4 Q9VSF3 CG7656-RA UBC12 0.126 19079254 Q9VUR4 O76460 CG7656-RA OKR 0.126 19079254 Q9VUR4 Q27297 CG7656-RA SPN-A 0.126 19079254