PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Rpb4 CG14353-RA 22036573 biogrid exp prp8 CG14353-RA 22036573 biogrid exp G G G G G CG7737, isoform A, LD46713p CG14353-RA 22036573 biogrid exp G G G G CG16908 CG14353-RA 22068330 intact exp G CG6674, isoform A, LD44422p CG14353-RA 22036573 biogrid exp G G G G G HIP-R CG14353-RA 22036573 biogrid exp fau CG14353-RA 14605208 biogrid,i2d,mint,intact exp G G G G G CG14353-RA ecd 22036573 biogrid exp G G G G G CG4849, LD28793p CG14353-RA 22036573 biogrid exp G G G G G Autophagy-specific gene 7, isoform A, RE27292p CG14353-RA ortho G G G G G l(3)01239 CG14353-RA ortho G G G G G Pih1D1, isoform D CG14353-RA ortho G G G G G CanA1 CG14353-RA ortho CG14353-RA CG3356, LP03102p ortho G G G G G FI17138p1, Spaghetti CG14353-RA ortho G G G G G Cctgamma CG14353-RA ortho G G G G G Ribosome biogenesis protein WDR12 homolog CG14353-RA ortho G G G G Probable phosphomevalonate kinase, PMKase CG14353-RA ortho G G G G G RpI1 CG14353-RA ortho G G G G G l(2)35Bc CG14353-RA ortho G flw CG14353-RA ortho G G G G G Sin-RA CG14353-RA ortho G G G G G Vps25 CG14353-RA ortho G G G G G emb CG14353-RA ortho G G G G G CG14353-RA shu ortho G HERC2 CG14353-RA ortho G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VVM7 Q9VGX3-2 - 14605208 - X 2 Q9VVM7 Q9VGX3-4 two hybrid 14605208 direct interaction X 2 Q9VVM7 Q9W032 affinity chromatography technology 22036573 physical association X 2 Q9VVM7 A1Z8U0 affinity chromatography technology 22036573 physical association X 2 Q7K4C2 Q9VVM7 affinity chromatography technology 22036573 physical association X 2 Q9VVM7 Q7KSD8-2 affinity chromatography technology 22036573 physical association X 2 Q9VVM7 Q9VT74 affinity chromatography technology 22036573 physical association X 2 C4NYP8 Q9VVM7 affinity chromatography technology 22036573 physical association X 2 Q9VAX8 Q9VVM7 affinity chromatography technology 22036573 physical association X 2 Q9VGX3 Q9VVM7 two hybrid 14605208 physical association X 2 Q9VVM7 anti tag coimmunoprecipitation 22068330 association C 10 Q9VVM7 anti tag coimmunoprecipitation 22068330 association C 10 Q9VVM7 Q9VGX3-2 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B fau CG14353-RA MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|MI:0471(mint)|(intact)|(biogrid) DIP_14448|MINT_18345|UniProt_47762|BIOGRID_31543 -|null|null|prey -|prey|prey|bait CG7737 CG14353-RA MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_73374 bait prey CG14353-RA Prp8 MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_71501 prey bait Rpb4 CG14353-RA MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_69342 prey bait CG6674 CG14353-RA MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_69962 bait prey ecd CG14353-RA MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_65511 bait prey CG4849 CG14353-RA MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_70603 prey bait CG14353-RA HIP MI:0004(affinity chromatography technology) 22036573 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_66685 prey bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VVM7 Q9VGX3 CG14353-RA FAU 0.033 14605208 Q9VVM7 Q9VH80 CG14353-RA Q9VH80 0.126 22068330 Q9VVM7 C0HK94 CG14353-RA C0HK94 0.183 14605208