PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus tws CG2926, isoform A 25294943 intact exp G G G G G G G Fas2 CG2926, isoform A 21447707,25294943 biogrid,intact exp G G G G G CG8319, LP19870p CG2926, isoform A 14605208 biogrid,i2d,mint,intact exp G Mer CG2926, isoform A 15710747 biogrid,i2d,intact exp G G G G G G spn-A CG2926, isoform A 15710747 biogrid,i2d,intact exp G G G G G G flw CG2926, isoform A 21447707,25294943 biogrid,intact exp G G G G G G G CG16812, LD36945p CG2926, isoform A 14605208 biogrid,i2d,mint,intact exp G G G G G G G CG2926, isoform A Rcd5 14605208 biogrid,i2d,mint,intact exp G G G G G G G sgg CG2926, isoform A 21447707,25294943 biogrid,intact exp G G CG10654, isoform B CG2926, isoform A 14605208 biogrid,i2d,mint,intact exp G G AT06251p, CG5478 CG2926, isoform A 14605208 biogrid,i2d,mint,intact exp G Hsc70-4 CG2926, isoform A 14605208 biogrid,i2d,mint,intact exp G G G G G G G CG2926, isoform A CG5059-PA, isoform A, RE48077p 25294943 intact exp G G G G G G G CG6316 CG2926, isoform A 14605208 biogrid,i2d,mint,intact exp G G G G G G G CG7341-RB CG2926, isoform A 21447707,25294943 biogrid,intact exp G G G G G G G P53 protein long form variant 1, p53, isoform B CG2926, isoform A 15710747 biogrid,i2d,mint,intact exp G G G G G G G CG2926, isoform A Jumonji, AT rich interactive domain 2 14605208 biogrid,i2d,mint,intact exp G G G G G G Traf-like CG2926, isoform A 14605208 biogrid,i2d,mint,intact exp G G G mei-S332 CG2926, isoform A 14605208 biogrid,i2d,mint,intact exp G G Rpt2 CG2926, isoform A 14605208 biogrid,i2d,mint,intact exp G G G G G G G Thrombospondin, isoform A, Thrombospondin, isoform F CG2926, isoform A 25294943 intact exp Moe CG2926, isoform A 15710747 biogrid,i2d,intact exp G G G G G G G EG:BACR42I17.4 CG2926, isoform A 14605208 biogrid,i2d,mint,intact exp G CG2926, isoform A CG3294, isoform A 14605208 biogrid,i2d,mint,intact exp G G Par-1, isoform P CG2926, isoform A 14605208 intact exp G G G G G G G ptc CG2926, isoform A 15710747 biogrid,i2d,intact exp rad23 CG2926, isoform A 14605208 biogrid,i2d,mint,intact exp G G G G G G G kn CG2926, isoform A 15710747 biogrid,i2d exp G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VNE0 Q9V3A3 - 14605208 - X 2 Q9VNE0 Q8IMB7 - 14605208 - X 2 Q9VNE0 Q9VZJ3 - 14605208 - X 2 Q9VNE0 Q9VK18 - 14605208 - X 2 Q9VNE0 P18502 - 15710747 - X 2 Q9VNE0 Q24564 - 15710747 - X 2 Q9VNE0 - 14605208 - X 2 Q9VNE0 P46150-2 - 15710747 - X 2 Q9VNE0 Q9N6D8 - 15710747 - X 2 Q9VNE0 Q9N6D8 - 15710747 - X 2 Q9VNE0 Q9VTY7 - 14605208 - X 2 Q9VNE0 C6SV45 - 15710747 - X 2 Q9VNE0 P56721-2 - 15710747 - X 2 Q9VNE0 Q9VF09 - 14605208 - X 2 Q9VNE0 Q86BN2 - 14605208 - X 2 Q9VNE0 Q9VT00 - 14605208 - X 2 Q9VNE0 Q9VXG5 - 14605208 - X 2 Q9VNE0 P48601 - 14605208 - X 2 Q9VNE0 Q8SZY9 - 14605208 - X 2 Q9VNE0 Q24141 - 14605208 - X 2 Q9VNE0 Q9VHA4 - 14605208 - X 2 C7LA75 Q9VNE0 two hybrid 14605208 direct interaction X 2 Q9VNE0 Q9VZJ3 two hybrid 14605208 direct interaction X 2 Q9VNE0 Q8IMB7 two hybrid 14605208 direct interaction X 2 Q9VNE0 Q9V3A3 two hybrid 14605208 direct interaction X 2 Q9VNE0 C7LAH9 two hybrid 15710747 direct interaction X 2 Q9VNE0 E2QCN0 two hybrid 15710747 direct interaction X 2 Q9VNE0 Q24564 two hybrid 15710747 direct interaction X 2 Q9VNE0 P18502 two hybrid 15710747 direct interaction X 2 Q9VNE0 Q9VK18 two hybrid 14605208 direct interaction X 2 Q9VNE0 Q9VTY7 two hybrid 14605208 direct interaction X 2 Q9VNE0 Q8SZY9 two hybrid 14605208 direct interaction X 2 Q9VNE0 Q86BN2 two hybrid 14605208 direct interaction X 2 Q9VNE0 Q9VT00 two hybrid 14605208 direct interaction X 2 Q9VNE0 Q8IR14 two hybrid 14605208 direct interaction X 2 Q9VNE0 P48601 two hybrid 14605208 direct interaction X 2 Q9VNE0 Q9VF09 two hybrid 14605208 direct interaction X 2 Q9VNE0 Q9VHA4 two hybrid 14605208 direct interaction X 2 Q9VNE0 two hybrid 15710747 direct interaction X 2 Q9VNE0 C6SV45 two hybrid 15710747 direct interaction X 2 Q9VNE0 Q24141 two hybrid 14605208 direct interaction X 2 C7LA75 Q9VNE0 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VZJ3 two hybrid 14605208 physical association X 2 Q9VNE0 Q9V3A3 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VK18 two hybrid 14605208 physical association X 2 Q9VNE0 two hybrid 14605208 physical association X 2 Q9VNE0 P46150-4 two hybrid 15710747 physical association X 2 Q9VNE0 P46150-4 two hybrid 15710747 physical association X 2 Q9VNE0 P18502 two hybrid 15710747 physical association X 2 Q9VNE0 Q24564 two hybrid 15710747 physical association X 2 Q9V3W9 Q9VNE0 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VTY7 two hybrid 14605208 physical association X 2 Q9VNE0 Q8SZY9 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VR26 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VT00 two hybrid 14605208 physical association X 2 Q9VNE0 Q8IR14 two hybrid 14605208 physical association X 2 Q9VNE0 P48601 two hybrid 14605208 physical association X 2 Q9VNE0 Q24141 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VF09 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VHA4 two hybrid 14605208 physical association X 2 Q9VNE0 Q9N6D8 two hybrid 15710747 physical association X 2 Q9VNE0 Q9N6D8 two hybrid 15710747 physical association X 2 Q9VNE0 C6SV45 two hybrid 15710747 physical association X 2 C7LA75 Q9VNE0 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VZJ3 two hybrid 14605208 physical association X 2 Q9VNE0 Q9V3A3 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VK18 two hybrid 14605208 physical association X 2 Q9VNE0 Q960H6 two hybrid 14605208 physical association X 2 Q9VNE0 M9NG50 two hybrid fragment pooling approach 15710747 physical association X 2 Q9VNE0 M9NG50 two hybrid fragment pooling approach 15710747 physical association X 2 Q9VNE0 Q24564 two hybrid fragment pooling approach 15710747 physical association X 2 Q9VNE0 Q8IMZ4 two hybrid fragment pooling approach 15710747 physical association X 2 Q9V3W9 Q9VNE0 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VTY7 two hybrid 14605208 physical association X 2 Q9VNE0 A1ZBL7 two hybrid 14605208 physical association X 2 Q9VNE0 Q8SZY9 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VR26 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VT00 two hybrid 14605208 physical association X 2 Q9VNE0 P48601 two hybrid 14605208 physical association X 2 Q9VNE0 Q24141 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VF09 two hybrid 14605208 physical association X 2 Q9VNE0 Q9VHA4 two hybrid 14605208 physical association X 2 Q9VNE0 Q8IGE8 two hybrid fragment pooling approach 15710747 physical association X 2 Q9VNE0 C6SV45 two hybrid fragment pooling approach 15710747 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CG5478 CG2926 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact) BIOGRID_43653|MINT_12090|UniProt_25822 prey|prey|prey bait|bait|bait ptc CG2926 MI:0018(two hybrid) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0465(dip) DIP_26912 - - CG3294 CG2926 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0465(dip) DIP_20100 - - p53 CG2926 MI:0399(two hybrid fragment pooling approach) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_41749 bait prey Traf-like CG2926 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact)|MI:0465(dip) MINT_12087|UniProt_25819|DIP_20103 prey|prey|- bait|bait|- Pros26.4 CG2926 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(biogrid)|MI:0465(dip)|(intact) MINT_12088|BIOGRID_43652|DIP_20104|UniProt_25820 prey|prey|-|prey bait|bait|-|bait Mer CG2926 MI:0399(two hybrid fragment pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|MI:0465(dip) UniProt_42665|BIOGRID_62833|DIP_27693 bait|bait|- prey|prey|- Q9V8V6 CG2926 MI:0398(two hybrid pooling approach) 14605208 taxid:0() taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0471(mint) MINT_12082 prey bait mei-S332 CG2926 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(biogrid)|(intact) DIP_20105|MINT_12089|BIOGRID_32677|UniProt_25821 -|prey|prey|prey -|bait|bait|bait CG8319 CG2926 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact) BIOGRID_43654|MINT_12091|UniProt_25823 prey|prey|prey bait|bait|bait Rad23 CG2926 MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|MI:0465(dip) BIOGRID_42746|DIP_18737 bait|- prey|- ptc CG2926 MI:0399(two hybrid fragment pooling approach) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_41930 bait prey p53 CG2926 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint) BIOGRID_61995|MINT_19541|MINT_19742|MINT_19340 bait|bait|bait|bait prey|prey|prey|prey Moe CG2926 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0399(two hybrid fragment pooling approach)|MI:0399(two hybrid fragment pooling approach) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(biogrid)|(intact)|(intact) DIP_26805|BIOGRID_62224|UniProt_41782|UniProt_41783 -|bait|bait|bait -|prey|prey|prey CG6316 CG2926 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0465(dip)|(biogrid)|MI:0471(mint) UniProt_25815|DIP_20099|BIOGRID_43647|MINT_12083 prey|-|prey|prey bait|-|bait|bait Rad23 CG2926 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_56663|MINT_10888 prey|prey bait|bait Traf-like CG2926 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_43651 prey bait Hsc70-4 CG2926 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|(intact)|(biogrid)|MI:0465(dip) MINT_12086|UniProt_25817|BIOGRID_43650|DIP_20102 prey|prey|prey|- bait|bait|bait|- CG16812 CG2926 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|(biogrid)|(intact) MINT_9390|BIOGRID_32121|UniProt_61073 prey|bait|prey bait|prey|bait CG2926 Jarid2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0465(dip)|(biogrid)|MI:0471(mint) UniProt_25818|DIP_20101|BIOGRID_43649|MINT_12085 bait|-|bait|bait prey|-|prey|prey CG2926 par-1 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_25814 bait prey CG2926 CG10654 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0465(dip)|MI:0471(mint) UniProt_59351|DIP_7279|MINT_22625 bait|-|bait prey|-|prey EG:BACR42I17.4 CG2926 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|MI:0471(mint) UniProt_55340|BIOGRID_30417|MINT_24490 bait|bait|bait prey|prey|prey CG2926 Rcd5 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(biogrid)|(intact)|MI:0471(mint) DIP_9170|BIOGRID_36567|UniProt_55254|MINT_24406 -|prey|bait|bait -|bait|prey|prey spn-A CG2926 MI:0018(two hybrid)|MI:0399(two hybrid fragment pooling approach)|MI:0018(two hybrid) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0465(dip) BIOGRID_61996|UniProt_42320|DIP_27306 bait|bait|- prey|prey|- CG2926 CG3294 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0471(mint)|(biogrid) UniProt_25816|MINT_12084|BIOGRID_43648 bait|bait|bait prey|prey|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VNE0 Q8SZY9 Q9VNE0 CG6316 0.183 14605208 Q9VNE0 Q9VMV9 Q9VNE0 RTNL1 0.236 25294943,21447707 Q9VNE0 Q24564 Q9VNE0 MER 0.155 15710747 Q9VNE0 Q8T0U6 Q9VNE0 FLW 0.236 25294943,21447707 Q9VNE0 Q24141 Q9VNE0 MEI-S332 0.21 14605208 Q9VNE0 P34082 Q9VNE0 FAS2 0.236 25294943,21447707 Q9VNE0 Q8IPU8 Q9VNE0 Q8IPU8 0.236 25294943 Q9VNE0 P18431 Q9VNE0 SGG 0.332 25294943,21447707 Q9VNE0 P36872 Q9VNE0 TWS 0.126 25294943 Q9VNE0 Q960H6 Q9VNE0 TRAF-LIKE 0.183 14605208 Q9VNE0 Q9V3A3 Q9VNE0 EG:BACR42I17.4 0.183 14605208 Q9VNE0 Q9VF09 Q9VNE0 Q9VF09 0.183 14605208 Q9VNE0 Q9VHA4 Q9VNE0 Q9VHA4 0.183 14605208 Q9VNE0 Q9VK18 Q9VNE0 Q9VK18 0.183 14605208 Q9VNE0 Q9VM97 Q9VNE0 TSP 0.126 25294943 Q9VNE0 P11147 Q9VNE0 HSC70-4 0.21 14605208 Q9VNE0 P46150 Q9VNE0 MOE 0.126 15710747 Q9VNE0 P48601 Q9VNE0 RPT2 0.21 14605208 Q9VNE0 Q27297 Q9VNE0 SPN-A 0.155 15710747 Q9VNE0 Q8IGE8 Q9VNE0 PTC 0.126 15710747 Q9VNE0 Q8IMZ4 Q9VNE0 P53 0.126 15710747 Q9VNE0 Q9V3W9 Q9VNE0 RAD23 0.183 14605208 Q9VR26 Q9VNE0 Q9VR26 Q9VNE0 0.183 14605208 Q9VT00 Q9VNE0 JARID2 Q9VNE0 0.183 14605208 Q9VTY7 Q9VNE0 Q9VTY7 Q9VNE0 0.183 14605208 Q9VZJ3 Q9VNE0 RCD5 Q9VNE0 0.183 14605208 Q9VNE0 P18502 Q9VNE0 PTC 0.033 15710747 Q9VNE0 A1ZBL7 Q9VNE0 PAR-1 0.183 14605208