PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Fancd2, Fanconi anemia complementation group D2 protein AT07283p, Fancl, isoform A 20154706 biogrid,dip exp G Fanconi anemia complementation group I homologue AT07283p, Fancl, isoform A 20154706 biogrid exp AT07283p, Fancl, isoform A DNApol-alpha73 14605208 biogrid,i2d,mint,intact exp G sol AT07283p, Fancl, isoform A 14605208 biogrid,i2d,mint,intact exp G G G G AT07283p, Fancl, isoform A MED27 16603075 intact exp G G aop AT07283p, Fancl, isoform A 14605208 biogrid,i2d,mint,intact,dip exp G G G how AT07283p, Fancl, isoform A 14605208 biogrid,i2d,mint,intact exp G G RE21134p AT07283p, Fancl, isoform A i2d exp AT07283p, Fancl, isoform A CG32206-RB 14605208 biogrid,mint,intact exp Ribonuclease kappa, RNase K, RNase kappa AT07283p, Fancl, isoform A 14605208 biogrid,i2d,mint,intact,dip exp G G G G IP14020p AT07283p, Fancl, isoform A 20154706 dip exp AT07283p, Fancl, isoform A Putative homeodomain protein, RT01102p 14605208 biogrid,i2d,mint,intact exp CG7220-RB AT07283p, Fancl, isoform A 14605208 biogrid,i2d,mint,intact exp G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8T913 Q8T972 - 14605208 - X 2 Q8T913 - 14605208 - X 2 M9PC88 Q8T913 - 14605208 - X 2 Q8T913 - 14605208 - X 2 Q8T913 P27398-2 - 14605208 - X 2 Q9W1H7 Q8T913 - 14605208 - X 2 O01367-2 Q8T913 - 14605208 - X 2 Q8MSF5 Q8T913 - 14605208 - X 2 Q8T913 E1JIT0 two hybrid 14605208 direct interaction X 2 Q8T913 Q9VVY7 two hybrid 14605208 direct interaction X 2 Q8T913 pull down 20154706 direct interaction X 2 M9PC88 Q8T913 two hybrid 14605208 direct interaction X 2 Q8MYL1 Q8T913 pull down 20154706 direct interaction X 2 Q8T913 P27398 two hybrid 14605208 direct interaction X 2 Q8T913 A1Z8B5 two hybrid 14605208 direct interaction X 2 Q9W1H7 Q8T913 two hybrid 14605208 direct interaction X 2 Q9VB62 Q8T913 two hybrid 14605208 direct interaction X 2 Q8MSF5 Q8T913 two hybrid 14605208 direct interaction X 2 Q8T913 Q9VVY7 two hybrid 14605208 physical association X 2 Q8T913 Q8T972 two hybrid 14605208 physical association X 2 Q29QV6 Q8T913 pull down 20154706 direct interaction X 2 M9PC88 Q8T913 two hybrid 14605208 physical association X 2 Q8MYL1 Q8T913 pull down 20154706 direct interaction X 2 Q8T913 P27398 two hybrid 14605208 physical association X 2 Q8T913 two hybrid 14605208 physical association X 2 Q9W1H7 Q8T913 two hybrid 14605208 physical association X 2 B3DNL7 Q8T913 two hybrid 14605208 physical association X 2 Q8MSF5 Q8T913 two hybrid 14605208 physical association X 2 Q8T913 Q9VVY7 two hybrid 14605208 physical association X 2 Q8T913 Q8T972 two hybrid 14605208 physical association X 2 Q9VNG0 Q8T913 two hybrid array 16603075 physical association X 2 M9PC88 Q8T913 two hybrid 14605208 physical association X 2 Q8T913 P27398 two hybrid 14605208 physical association X 2 Q8T913 P27398 two hybrid 14605208 physical association X 2 Q9W1H7 Q8T913 two hybrid 14605208 physical association X 2 Q9VB62 Q8T913 two hybrid 14605208 physical association X 2 B3DNL7 Q8T913 two hybrid 14605208 physical association X 2 Q8MSF5 Q8T913 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B sol Fancl MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|(intact)|(biogrid)|MI:0465(dip)|(intact) MINT_26883|MINT_26882|UniProt_51179|BIOGRID_31007|DIP_11855|UniProt_51180 prey|bait|prey|prey|-|bait bait|prey|bait|bait|-|prey CG40127 Fancl MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|MI:0471(mint)|MI:0465(dip) UniProt_51183|BIOGRID_38203|MINT_26886|DIP_11858 prey|prey|prey|- bait|bait|bait|- how Fancl MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|MI:0471(mint)|(intact)|(biogrid) DIP_6300|MINT_17899|UniProt_58375|BIOGRID_34523 -|null|null|bait -|prey|prey|prey Fancd2 Fancl MI:0096(pull down) 20154706 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_64075 prey bait Fancl CG7220 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|(intact)|(biogrid)|MI:0471(mint) DIP_11860|UniProt_51186|BIOGRID_31009|MINT_26888 -|bait|bait|bait -|prey|prey|prey aop Fancl MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(biogrid)|MI:0465(dip)|(intact) MINT_26884|BIOGRID_38202|DIP_11856|UniProt_51181 bait|prey|-|bait prey|bait|-|prey Fancl DNApol-alpha73 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0471(mint)|MI:0465(dip)|(biogrid) UniProt_51184|MINT_26887|DIP_11859|BIOGRID_38204 prey|prey|-|bait bait|bait|-|prey Fancl MED27 MI:0018(two hybrid) 16603075 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_44688 prey bait Fancl CG32206-RB MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|MI:0465(dip)|(intact) BIOGRID_31008|MINT_26885|DIP_11857|UniProt_51182 bait|bait|-|bait prey|prey|-|prey Fancl PHDP MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|(intact)|(biogrid)|MI:0465(dip) MINT_23799|UniProt_54630|BIOGRID_36135|DIP_8547 bait|bait|prey|- prey|prey|bait|- Fancl FANCI MI:0096(pull down) 20154706 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_64076 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8T913 B3DNL7 FANCL HOW 0.033 14605208 Q8T913 Q8MSF5 FANCL Q8MSF5 0.21 14605208 Q8T913 O01367 FANCL HOW 0.183 14605208 Q9VB62 Q8T913 DNAPOL-ALPHA73 FANCL 0.183 14605208 Q9VNG0 Q8T913 MED27 FANCL 0.126 16603075 Q9VVY7 Q8T913 CG32206-RB FANCL 0.21 14605208 Q8T913 Q01842 FANCL AOP 0.21 14605208 Q8T972 Q8T913 Q8T972 FANCL 0.21 14605208 Q8T913 P27398 FANCL SOL 0.354 14605208 Q9W1H7 Q8T913 PHDP FANCL 0.21 14605208