PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Mpcp-RA CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p 19079254 intact exp G G G G G G G G G G CG9798 CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p 14605208 biogrid,i2d,mint,intact exp G G G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p CG34380, isoform D 14605208 biogrid exp G G ftz-f1 CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p 14605208 biogrid,i2d,mint,intact exp G G G G G G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p CG15239-RA 14605208 biogrid,i2d,mint,intact exp GH24511p, Ubiquitin activating enzyme 1, isoform A CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p ortho G G G G G G G G G G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p Nedd4 ortho G G G G G G G G G r CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p ortho G G CG9153-RB CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p ortho G G G G G G G G G G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p CG14646, isoform A, CG14646, isoform B, RE35255p ortho G G G G G G G G G G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p Tctp ortho G G G G G G G G G G Ubi-p63E CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p ortho G G G G G G G G G G RuvB-like helicase 2 CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p ortho G G G G G G G G G G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p CG4554 ortho G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p ortho G G G G G G G G G G betaTub56D CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p ortho G G G G G G G G G G E3 ubiquitin-protein ligase parkin CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p ortho G G G G G G G G G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p CG12099, isoform A, CG12099, isoform B, LD09551p ortho G G G G G G G G G G blw CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p ortho G G G G G G G G G G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p Ubc7 ortho G G G G G G G G G G CG17514, isoform A CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p ortho G G G G G G G G G G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p LD29171p, Sec71 ortholog ortho G G G G G G G G G G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p RuvB-like helicase 1 ortho G G G G G G G G G G Rab1-RA CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p ortho G G G G G G G G G G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p Protein-S-isoprenylcysteine O-methyltransferase ortho G G G G G G G CG5823, isoform A, CG5823, isoform B, HL05730p, RE16955p Adenylyltransferase and sulfurtransferase MOCS3 ortho G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9VEJ4 Q9VCY6 - 14605208 - X 2 Q9VEJ4 Q9W4P4 - 14605208 - X 2 Q9VEJ4 - 14605208 - X 2 Q9VEJ4 Q9VCY6 two hybrid 14605208 direct interaction X 2 A8DYR2 Q9VEJ4 two hybrid 14605208 direct interaction X 2 Q9VEJ4 P33244 two hybrid 14605208 direct interaction X 2 Q9VEJ4 Q9W4P4 two hybrid 14605208 direct interaction X 2 Q9VEJ4 Q9VCY6 two hybrid 14605208 physical association X 2 Q9VEJ4 Q9W4P4 two hybrid 14605208 physical association X 2 Q9VEJ4 two hybrid 14605208 physical association X 2 Q9VEJ4 P33244 two hybrid 14605208 physical association X 2 Q9VEJ4 Q9VCY6 two hybrid 14605208 physical association X 2 Q9VEJ4 Q9W4P4 two hybrid 14605208 physical association X 2 Q9VEJ4 P33244 two hybrid 14605208 physical association X 2 Q0E8E8 Q9VEJ4 two hybrid array 19079254 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CG5823 CG34380 MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_61660 prey bait ftz-f1 CG5823 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|MI:0471(mint) UniProt_50205|BIOGRID_45543|MINT_14793 bait|bait|bait prey|prey|prey CG5278 CG5823 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0471(mint)|(biogrid) UniProt_62105|MINT_15940|BIOGRID_33453 prey|prey|bait bait|bait|prey Mpcp CG5823 MI:0397(two hybrid array) 19079254 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_43322 bait prey CG5823 CG15239-RA MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_59929|MINT_8289 prey|prey bait|bait CG5823 Q9VMG2 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:0() MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact) MINT_12994|UniProt_26813 prey|prey bait|bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VEJ4 Q9VCY6 Q9VEJ4 CG5278-RA 0.183 14605208 Q9VEJ4 P33244 Q9VEJ4 FTZ-F1 0.183 14605208 Q9VEJ4 Q0E8E8 Q9VEJ4 MPCP 0.126 19079254 Q9W4P4 Q9VEJ4 CG15239-RA Q9VEJ4 0.183 14605208