PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RecQ4 wech 15710747 intact exp wech RecQ4 i2d exp G Fer1HCH-RD wech 25294943 intact exp G G G G G noi wech 14605208 biogrid,i2d,mint,intact,dip exp G G G G G wech CG7173 14605208 biogrid,i2d,mint,intact exp Multiple wing hairs, isoform C wech 14605208 biogrid,i2d,mint,intact exp G AGO1-RC wech 18528333 dip exp, ortho G G G G G wech Dcr-1 ortho G wech wech ortho G G G G G Nucleoporin 154kD, isoform A, Nucleoporin 154kD, isoform C, Nucleoporin 154kD, isoform D, Nup154 wech ortho G G G G G CASK wech ortho G G G G G wech Clp ortho G G G G wech Eukaryotic initiation factor 1A, isoform A, Eukaryotic initiation factor 1A, isoform B, Eukaryotic initiation factor 1A, isoform C, RE54849p ortho G G G G G wech lin-28 ortho Ubi-p63E wech ortho G G G G G Conserved oligomeric Golgi complex subunit 4, COG complex subunit 4 wech ortho G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9V4M2 Q9VSE6 - 15710747 - X 2 Q9V4M2 Q9VP16 - 14605208 - X 2 Q9V4M2 Q9W0J2 - 14605208 - X 2 Q9V4M2 O46106 - 14605208 - X 2 Q9V4M2 Q9VP16 two hybrid 14605208 direct interaction X 2 Q9V4M2 Q9W0J2 two hybrid 14605208 direct interaction X 2 Q9V4M2 O46106 two hybrid 14605208 direct interaction X 2 Q9V4M2 Q9VP16 two hybrid 14605208 physical association X 2 Q27IR0 Q9V4M2 anti tag coimmunoprecipitation 18528333 physical association X 2 Q9V4M2 Q9W0J2 two hybrid 14605208 physical association X 2 Q9V4M2 O46106 two hybrid 14605208 physical association X 2 Q9V4M2 Q9VP16 two hybrid 14605208 physical association X 2 Q9NH11 Q9V4M2 two hybrid fragment pooling approach 15710747 physical association X 2 Q9V4M2 Q9W0J2 two hybrid 14605208 physical association X 2 Q9V4M2 O46106 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B RecQ4 wech MI:0399(two hybrid fragment pooling approach) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_42385 bait prey wech mwh MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact) BIOGRID_39521|MINT_28745|UniProt_47107 prey|prey|prey bait|bait|bait wech CG7173 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0465(dip)|MI:0471(mint)|(intact) BIOGRID_41489|DIP_16867|MINT_9154|UniProt_60826 bait|-|prey|prey prey|-|bait|bait noi wech MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(biogrid)|(intact)|MI:0471(mint) DIP_16866|BIOGRID_41488|UniProt_60825|MINT_9153 -|prey|bait|bait -|bait|prey|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VP16 Q9V4M2 Q9VP16 WECH 0.21 14605208 Q9V4M2 O46106 WECH NOI 0.354 14605208 Q9V4M2 Q9NH11 WECH RECQ4 0.126 15710747 Q9W0J2 Q9V4M2 MWH WECH 0.21 14605208 Q9VA83 Q9V4M2 FER2LCH WECH 0.126 25294943