PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus th SD10041p 16887178 intact exp th CG4554 14605208 biogrid,i2d,mint,intact exp G th CG1274-PA, isoform A, GH25379p, Secretable thioredoxin peroxidase, Thioredoxin peroxidase 2, Thioredoxin peroxidase 2, isoform B, Thioredoxin peroxidase 2, isoform C unassigned4,12356728 biogrid,intact exp G G G G G G G G G G th BTB-VII protein domain 15710747 intact exp th EG:22E5.6 22036573 biogrid exp RpS27A th 12021768 biogrid exp G G G G G G G G G G th Tab2-RA 14605208 biogrid,intact exp G G G G G G G G th BTB-protein-VII, isoform F i2d exp G G G G G G G G G W th 12021771,10675328,10481910,12525502,unassigned4,12021769,14517550 biogrid,i2d,intact exp G th Endonuclease G, LD35517p 25139236 biogrid exp G G G G G G G G G G th Strica unassigned4 intact exp G G G sina th 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G th hpo unassigned4 intact exp G G G G G G G G G G th Iap2 17205079 biogrid exp G G G G G G G G G G Ice th 15580265,21145488 biogrid,i2d exp G G G G G G G G G G th Skl 11818065 intact exp G G th Nc 12021771,20700104,15710747,unassigned4,10675329,14517550 biogrid,i2d,mint,intact exp G G G G th rpr 12021771,10675328,unassigned4,12021769,11818065 biogrid,i2d,intact exp G th th 21145488 biogrid exp G G G G G G G G G G Rac1 th 15242648 i2d,intact exp G G G G G G G G G G eff th 12021769 intact exp G G G G G G G G G G chic th 15242648 i2d,intact exp G G G G G G G G G G th GM10337p unassigned4 intact exp th ik2-RB 16887178 biogrid exp G G th HtrA2 17557079 mint,intact exp G G G G Receptor protein serine/threonine kinase th unassigned4 intact exp G G G G G G G G G G th grim 23940367,12525502,unassigned4 biogrid,intact exp th Ubc12 21145488 biogrid exp G G G G G G G G G G th BcDNA.GH02435 12021768 biogrid exp G G G G G G G G G G th CG32772, isoform C, CG32772, isoform E, IP01388p 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G G Dcp-1 th 15580265,10481910,unassigned4 biogrid,i2d,intact exp G G G G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B th ik2 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 16887178 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0217(phosphorylation reaction)|MI:0217(phosphorylation reaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact) UniProt_44723|UniProt_85516|UniProt_44722|UniProt_44721 unspecified role|unspecified role|bait|prey unspecified role|unspecified role|prey|bait th morgue MI:0045(experimental interaction detection) pubmed:unassigned4 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_45900 unspecified role unspecified role th Tab2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|(intact)|(biogrid) DIP_10910|UniProt_64932|BIOGRID_37663 -|prey|bait -|bait|prey th ik2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16887178 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_75572|BIOGRID_75573|BIOGRID_75574 prey|bait|prey bait|prey|bait eff th MI:0096(pull down) 12021769 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_38877 bait prey th morgue MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12021768 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_75633|BIOGRID_75632 bait|prey prey|bait th dream MI:0045(experimental interaction detection) pubmed:unassigned4 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_45642 unspecified role unspecified role th BtbVII MI:0399(two hybrid fragment pooling approach) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_42267 bait prey th skl MI:0096(pull down) 11818065 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_38777 bait prey th Nc MI:0018(two hybrid)|MI:0045(experimental interaction detection)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0399(two hybrid fragment pooling approach)|MI:0007(anti tag coimmunoprecipitation) 10675329,12021771,14517550,15710747,20700104 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0220(ubiquitination reaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_39164|UniProt_45916|UniProt_39192|UniProt_39193|UniProt_39194|UniProt_38662|UniProt_38661|UniProt_38660|UniProt_39162|UniProt_41898|UniProt_45084 prey|unspecified role|bait|bait|prey|neutral component|prey|bait|bait|prey|bait bait|unspecified role|prey|prey|bait|neutral component|bait|prey|prey|bait|prey th CG32772 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|(intact)|MI:0465(dip)|(biogrid) MINT_25988|UniProt_64930|DIP_10908|BIOGRID_37661 prey|prey|-|bait bait|bait|-|prey th Q9V8T0 MI:0398(two hybrid pooling approach) 14605208 taxid:7227(Drosophila melanogaster) taxid:0() MI:0915(physical association) MI:0471(mint) MINT_25990 prey bait th rpr MI:0096(pull down)|MI:0096(pull down)|MI:0045(experimental interaction detection)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0676(tandem affinity purification) 10675328,11818065,12021769,12021771 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_38778|BIOGRID_60936|UniProt_46032|UniProt_38596|UniProt_38597|UniProt_38598|UniProt_38879|UniProt_39190 bait|prey|unspecified role|prey|prey|prey|prey|bait prey|bait|unspecified role|bait|bait|bait|bait|prey th tkv MI:0045(experimental interaction detection) pubmed:unassigned4 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_46107 unspecified role unspecified role th grim MI:0004(affinity chromatography technology)|MI:0045(experimental interaction detection) 23940367 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_77016|UniProt_45745 prey|unspecified role bait|unspecified role th hpo MI:0045(experimental interaction detection) pubmed:unassigned4 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_45794 unspecified role unspecified role Dcp-1 th MI:0045(experimental interaction detection)|MI:0096(pull down) 10481910 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_45592|UniProt_39081 unspecified role|prey unspecified role|bait th Jafrac2 MI:0096(pull down)|MI:0045(experimental interaction detection)|MI:0096(pull down) 12356728 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(intact)|(biogrid) BIOGRID_61011|UniProt_45830|BIOGRID_61009 bait|unspecified role|bait prey|unspecified role|prey RpS27A th MI:0004(affinity chromatography technology) 12021768 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_75634 prey bait th CG4554 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|(intact)|MI:0465(dip)|(biogrid) MINT_25989|UniProt_64931|DIP_10909|BIOGRID_37662 prey|prey|-|bait bait|bait|-|prey th BtbVII MI:0018(two hybrid) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0465(dip) DIP_27255 - - th HtrA2 MI:0428(imaging technique)|MI:0428(imaging technique) 17557079 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_44947|MINT_19232 bait|bait prey|prey Ice th MI:0004(affinity chromatography technology) 15580265 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_75465 prey bait Rac1 th MI:0096(pull down) 15242648 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_38993 prey bait sina th MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|(intact)|MI:0471(mint)|(biogrid) DIP_10911|UniProt_64933|MINT_25991|BIOGRID_37664 -|bait|bait|prey -|prey|prey|bait W th MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0045(experimental interaction detection)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0676(tandem affinity purification) 10481910,10675328,12021769,12021771,14517550 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_38600|UniProt_38601|UniProt_38599|UniProt_46120|BIOGRID_60935|UniProt_38663|UniProt_38878|UniProt_39083|UniProt_39082|UniProt_39191 bait|bait|bait|unspecified role|bait|neutral component|bait|prey|prey|prey prey|prey|prey|unspecified role|prey|neutral component|prey|bait|bait|bait chic th MI:0096(pull down)|MI:0096(pull down) 15242648 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_38991|UniProt_38996 prey|prey bait|bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q86PE7 Q24306 IK2 TH 0.396 16887178 Q24306 P21461 TH SINA 0.332 14605208 Q24475 Q24306 RPR TH 0.814 unassigned4,12021769,11818065,12021771,10675328 Q9XYF4 Q24306 NC TH 0.939 unassigned4,20700104,10675329,15710747,14517550,12021771 Q24306 Q24106 TH W 0.908 10481910,unassigned4,12525502,12021769,14517550,12021771,10675328 Q24306 P25843 TH CHIC 0.376 15242648 Q9VFJ3 Q24306 HTRA2 TH 0.21 17557079 Q24306 P40792 TH RAC1 0.21 15242648 Q9VVP8 Q24306 SKL TH 0.21 11818065 Q9VZU6 Q24306 BTBVII TH 0.126 15710747 Q24306 O01382 TH ICE 0.21 15580265 Q24306 O43909 TH EXTL3 0.21 15580265 Q24306 P15357 TH RPS27A 0.21 12021768 Q24306 P25867 TH EFF 0.21 12021769 Q24307 Q24306 IAP2 TH 0.523 17205079 Q6NQZ7 Q24306 TAB2 TH 0.183 14605208 Q7KHK9 Q24306 DREAM TH 0.126 unassigned4 Q86NX0 Q24306 MORGUE TH 0.126 unassigned4 Q8T0S6 Q24306 HPO TH 0.126 unassigned4 Q9V3Q4 Q24306 JAFRAC2 TH 0.126 unassigned4 Q9W246 Q24306 Q9W246 TH 0.183 14605208 Q9W4F9 Q24306 Q9W4F9 TH 0.183 14605208 Q24326 Q24306 TKV TH 0.126 unassigned4 Q24570 Q24306 GRIM TH 0.454 unassigned4,23940367,12525502 Q24306 O02002 TH DCP-1 0.454 10481910,unassigned4,15580265