PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CG31855, isoform B, CG31855-PA, RE70574p pic 22036573 biogrid exp G G G G G G G G G G PAPLA1 pic 25294943 intact exp G G G G G G G G G G BRWD3 pic 22036573 biogrid exp G G G G G G G G G G DNApol-delta pic 15710747 biogrid,i2d,intact exp G G G G polo pic 15710747 biogrid,i2d,intact exp G G l(2)dtl pic 22036573 biogrid exp G slmb pic ortho G G G G G G G G G Fas-associated factor, isoform A, Fas-associated factor, isoform B, GH16914p pic ortho G G G G G G G G G G Bx42 pic ortho G G G G G G G G G G CSN7 pic ortho G G G G G G G G G G adp-RA pic ortho G G G G G G G G G G Rpb11 pic ortho G G G G G G G G G G CG5708, isoform B, CG5708, isoform C, CG5708-PA, isoform A, LD11652p pic ortho G G G G G G G G G G GH11602p, Gcn5 ortholog pic ortho G G G G G G G G G E(z) pic ortho G G G G G G G pic CG8184, isoform H ortho G G G G G G G G G G AT18160p, CG9945, isoform A, CG9945, isoform B pic ortho G G G G G Vha14-1 pic ortho G G G G G G G G G G CG8209, GM09977p pic ortho G G G G G G G G G G Raptor, isoform B, Raptor, isoform C pic ortho mei-9 pic ortho G Cullin 5, FI20194p1 pic ortho G G G G G G G G G G aurA pic ortho G G Retinoblastoma-binding protein 5 homolog pic ortho G G G G G Mtor pic ortho G G G G G G G G G G Fbw5, GH09073p pic ortho G G G G G G G G G G GH24511p, Ubiquitin activating enzyme 1, isoform A pic ortho G G G G G G G G G G DCN1-like protein pic ortho G G G G G G G G G G WD repeat-containing protein 26 homolog pic ortho G G G G G G G G G G CG14220-RA pic ortho G G G G G hyd pic ortho G G G G G G G G G G pic pic ortho G G G G G G G G G G CG17698-RA pic ortho G G G G CSN8 pic ortho G G G G G G G G G G PCNA pic ortho G G G sbr pic ortho G G G G G G G G G G Xpac pic ortho G G G G G G Strip pic ortho G G G G G G G G G G lin19 pic ortho G G G G G G G G G G No child left behind pic ortho G G G G EG:BACR7A4.16 pic ortho G Tor pic ortho G G G G G G G G G G Atg6 pic ortho G G G G G G G G G G Cullin 3, isoform F, FI19425p1 pic ortho G G G G G G G G G G Dyrk3 pic ortho G G G G G G G G G RpA-70 pic ortho G G G G G G G G G G Cell division cycle 5 ortholog, isoform A, Cell division cycle 5 ortholog, isoform B, LD21614p pic ortho G G G G G G G CSN1b pic ortho G G G G G G G G G G Ubi-p63E pic ortho G G G G G G G G G G GH01161p, TNF-receptor-associated factor 6 pic ortho G G G G G G G G G CG3000-PA, isoform A, GH07620p, RE20929p, Retina aberrant in pattern, isoform B pic ortho G G G G G G G G G G Rpd3 pic ortho G G G G G G G G G Su(z)12 pic ortho G G G G G G G G G G Methyl methanesulfonate sensitivity 4 ortholog pic ortho G 14-3-3epsilon pic ortho G G G G G G G G G G CG3436, isoform A, CG3436, isoform C, GM13767p pic ortho G G G G G G G G G G Cand1 pic ortho G G G G G G G G G G Caf1 pic ortho G G G G G G G G G G ILK pic ortho G G G G G G G G G G noi pic ortho G G G G G G G G G G Nucleoporin 43kD pic ortho G G G G G G G G Nedd8 pic ortho G G G G G G G G G G Pros-alpha-6T pic ortho G Sirt6 pic ortho G Gprk2 pic ortho G G G G G G G G Ercc1, Nucleotide excision repair protein ERCC1 pic ortho G CG7275-PA, LD28275p pic ortho G G G G G G G G G G IP16020p, Phosphatase PTEN, Pten, isoform B, Pten, isoform D, Pten, isoform G, Pten, isoform H pic ortho G G G G G G G G G Hr96 pic ortho G G G G G G G G G G Arp5 pic ortho G G G G G G G CG10418-PA pic ortho G G G G G G G G G G pUf68 pic ortho G G G G G G G G G G CMP-sialic acid synthase pic ortho G G G His3, His3:CG31613, His3:CG33803, His3:CG33806, His3:CG33809, His3:CG33812, His3:CG33815, His3:CG33818, His3:CG33821, His3:CG33824, His3:CG33827, His3:CG33830, His3:CG33833, His3:CG33836, His3:CG33839, His3:CG33842, His3:CG33845, His3:CG33848, His3:CG33851, His3:CG33854, His3:CG33857, His3:CG33860, His3:CG33863, His3:CG33866 pic ortho 14-3-3zeta pic ortho G G G G G G G CG5555, isoform A, GH07062p pic ortho G G G G G G G G G G Tyrosine--tRNA ligase pic ortho G G G G G G G G G G hoip pic ortho Grip84 pic ortho G G G G G G G G G RpII215 pic ortho G G G G G G G G G G CG32672-PA, LD05816p pic ortho G G G G G G G G G G alc-RA pic ortho RanBPM pic ortho G G G G G G G G G RpS9 pic ortho G G G G G G G G G G Mer pic ortho G G G G G G G G G Probable 6-phosphogluconolactonase, 6PGL pic ortho G G G G G G G G G G grp pic ortho G G G G G G G G G G baf pic ortho G G G G G G G G G G FI11703p, Rad21 mitotic cohesin, Verthandi, isoform A pic ortho G G G G G G G G G G LP09464p, Nucleoporin 133kD pic ortho G G G G G G G arm pic ortho G G G G G G G G G G CG14614-RA pic ortho G G G G G G G G G Sirt7 pic ortho G G G G G CG9890, LD46465p pic ortho G G G G G G G G G wds pic ortho G G G G G G G G mib1 pic ortho G G G G G G G G G G mahj pic ortho G G G G G G G G G RpS7 pic ortho G G G G G G G G G G Mcm10 pic ortho G G pic CSN5 ortho G G G G G G G G G G CG3313, isoform A, CG3313, isoform B, LD21841p pic ortho G G G G Ino80 pic ortho G G G G G G G G G CSN4 pic ortho G G G G G G G G G G Putative rRNA methyltransferase pic ortho G G G G Skp2, isoform A, Skp2, isoform E pic ortho G G G G AGO1-RC pic ortho G G G G G G G G G Sin3A pic ortho G G G G G G G G G G dod pic ortho G G G G Mcm5 pic ortho G CG10932, isoform A, CG10932, isoform B, LD24105p pic ortho G G G G G G G G G Cullin 4, isoform A, Cullin 4, isoform B, FI05474p, LP02965p pic ortho G G G G G G G G G G Lethal (2) 09851, isoform A, Lethal (2) 09851, isoform B, RE17371p, RE55020p pic ortho G G G G G G G G G G Roc1a pic ortho G G G G G G G G G CG31251, RE67940p pic ortho G G G CG2774-RA pic ortho G G G G G G G G G G CG9273 protein, CG9273-PA, GM04951p, Replication protein A2, isoform A, Replication protein A2, isoform B pic ortho G G G EG:BACR7A4.17 pic ortho G G G G G G G G G CSN6 pic ortho G G G G G G G G G G CSN3 pic ortho G G G G G G G G G G Rpb4 pic ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P54358 Q9XYZ5 - 15710747 - X 2 P52304 Q9XYZ5 - 15710747 - X 2 P54358 Q9XYZ5 two hybrid 15710747 direct interaction X 2 Q24371 Q9XYZ5 affinity chromatography technology 22036573 physical association X 2 P52304 Q9XYZ5 two hybrid 15710747 direct interaction X 2 Q9XYZ5 Q9VC96 affinity chromatography technology 22036573 physical association X 2 Q8IP73 Q9XYZ5 affinity chromatography technology 22036573 physical association X 2 P54358 Q9XYZ5 two hybrid fragment pooling approach 15710747 physical association X 2 P52304 Q9XYZ5 two hybrid fragment pooling approach 15710747 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9XYZ5 P54358 PIC DNAPOL-DELTA 0.286 15710747 Q9XYZ5 Q9VLS7 PIC Q9VLS7 0.126 25294943 Q9XYZ5 P52304 PIC POLO 0.286 15710747 Q9XYZ5 Q24371 PIC L(2)DTL 0.126 22036573