PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Uba3 aralar1 14605208 biogrid,i2d,mint,intact exp G G G G G G G G G Cullin 3, isoform F, FI19425p1 Uba3 21931660 biogrid exp G G G G G G G G G G Uba3 CG13407 14605208 biogrid,i2d,mint,intact exp lin19 Uba3 21931660 biogrid exp, ortho G G G G G G G G G G Uba3 APP-BP1 21931660,14605208 biogrid,i2d,mint,intact exp, ortho G G G G G G G G Uba3 clot ortho G G G G G G G G G G Uba3 Pect-RB ortho G G G G G G G G G G Uba3 Uba3 ortho G G G G G G G G G G Uba3 Probable methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase ortho G G G G G G G G G G Uba3 CG3909 ortho G G G G G G G G G G Uba3 twf ortho G G G G G G G G G G rad23 Uba3 ortho G G G G G G G G G G Ahcy13 Uba3 ortho G G G G G G G G G G Uba3 CG9149 ortho G G G G G G G G G G Jafrac1 Uba3 ortho G G G G G G G G G G Ubi-p63E Uba3 ortho G G G G G G G G G G Autophagy-specific gene 7, isoform A, RE27292p Uba3 ortho G G G G G G G G G G Uba3 FBXO11 ortho G G G G G G G G G Uba3 Nedd8 ortho G G G G G G G G G G PAPS synthetase, isoform D Uba3 ortho G G G G G G G G G Uba3 CG9389, GH15479p ortho G UbcE2H Uba3 ortho G G G G G G G G G G emb Uba3 ortho G G G G G G G G G G Uba3 Cullin 5, FI20194p1 ortho G G G G G G G G G G Uba3 Su(var)3-3 ortho G G G G G G GH01724p, p47 Uba3 ortho G G G G G G G G G G Uba3 CG2091, GH04919p ortho G G G G G G G G Uba3 LD23155p, Rabaptin-5 ortho G G G G G G G G G G CG2277, isoform A, CG2277, isoform B, LD24878p Uba3 ortho G G G G G G G G G G Ubiquitin-fold modifier-conjugating enzyme 1 Uba3 ortho G G G G G G G G G G Uba3 Ubc12 ortho G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9V6U8 Q9VTE9 - 14605208 - X 2 Q9VA73-3 Q9V6U8 - 14605208 - X 2 Q9VD47 Q9V6U8 - 14605208 - X 2 Q9V6U8 Q24311 enzymatic study 21931660 direct interaction X 2 Q9V6U8 Q9VTE9 affinity chromatography technology 21931660 physical association X 2 Q9V6U8 Q8IP45 enzymatic study 21931660 direct interaction X 2 Q9V6U8 Q9VTE9 two hybrid 14605208 direct interaction X 2 Q9VA73 Q9V6U8 two hybrid 14605208 direct interaction X 2 Q9VD47 Q9V6U8 two hybrid 14605208 direct interaction X 2 Q9V6U8 Q9VTE9 two hybrid 14605208 physical association X 2 Q9VA73 Q9V6U8 two hybrid 14605208 physical association X 2 Q9VD47 Q9V6U8 two hybrid 14605208 physical association X 2 Q9V6U8 Q9VTE9 two hybrid 14605208 physical association X 2 Q9VA73 Q9V6U8 two hybrid 14605208 physical association X 2 Q9VD47 Q9V6U8 two hybrid 14605208 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CG13343 APP-BP1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0004(affinity chromatography technology) 14605208,21931660 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|MI:0465(dip)|MI:0471(mint)|(biogrid) UniProt_52194|BIOGRID_31210|DIP_12870|MINT_27859|BIOGRID_75365 bait|bait|-|bait|prey prey|prey|-|prey|bait CG13343 eIF5 MI:0004(affinity chromatography technology) 22271760 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_632967 prey bait lin19 CG13343 MI:0004(affinity chromatography technology) 21931660 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_75366 prey bait Cul-3 CG13343 MI:0004(affinity chromatography technology) 21931660 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_75367 prey bait CG13343 CG13407 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0465(dip)|(intact)|MI:0471(mint)|(biogrid) DIP_12868|UniProt_52192|MINT_27858|BIOGRID_31208 -|prey|prey|bait -|bait|bait|prey CG13343 aralar1 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0471(mint)|MI:0465(dip)|(biogrid) UniProt_52193|MINT_18262|DIP_12869|BIOGRID_31209 prey|prey|-|bait null|null|-|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9VTE9 Q9V6U8 APP-BP1 UBA3 0.49 21931660,14605208 Q9V6U8 Q24311 UBA3 LIN19 0.309 21931660 Q9VD47 Q9V6U8 Q9VD47 UBA3 0.183 14605208 Q9VA73 Q9V6U8 ARALAR1 UBA3 0.354 14605208