PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ab Grasp65 14605208 biogrid,i2d,mint,intact exp G G G Hira ab 19782028 biogrid exp G G ab so 14605208 biogrid,i2d,mint,intact,dip exp G ptc ab 15710747 biogrid,i2d,intact,dip exp spi ab 15710747 biogrid,i2d,mint,intact,dip exp G G G Drongo, isoform F ab 14605208 biogrid,i2d,mint,intact exp G G G ab CG3815-PA, GH06635p 19782028 biogrid exp G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants A4V0W1 Q24174 - 15710747 - X 2 Q24174 P18502 - 15710747 - X 2 Q27350 Q24174 two hybrid 14605208 physical association X 2 A4V0W1 Q24174 two hybrid 15710747 physical association X 2 Q9VW57 Q24174 two hybrid 14605208 physical association X 2 Q24174 Q9VPU3 two hybrid 14605208 physical association X 2 Q24174 P18502 two hybrid 15710747 physical association X 2 A4V0W1 Q24174 two hybrid fragment pooling approach 15710747 physical association X 2 Q8IGE8 Q24174 two hybrid fragment pooling approach 15710747 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B ab CSN4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 20106980,21987634 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0799(additive genetic interaction defined by inequality)|MI:0799(additive genetic interaction defined by inequality)|MI:0794(synthetic genetic interaction defined by inequality) (biogrid)|(biogrid)|(biogrid) BIOGRID_625289|BIOGRID_624012|BIOGRID_552356 prey|bait|prey bait|prey|bait ab del MI:0004(affinity chromatography technology) 21987634 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0799(additive genetic interaction defined by inequality) (biogrid) BIOGRID_623527 bait prey rux ab MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19325107 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0799(additive genetic interaction defined by inequality)|MI:0799(additive genetic interaction defined by inequality) (biogrid)|(biogrid) BIOGRID_576189|BIOGRID_577697 prey|bait bait|prey ab drongo MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|(biogrid)|(intact) MINT_18885|BIOGRID_44982|UniProt_49460 null|prey|null bait|bait|bait Hira ab MI:0004(affinity chromatography technology) 19782028 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_63750 bait prey ab Grasp65 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact)|MI:0465(dip) BIOGRID_46072|MINT_18981|UniProt_61585|DIP_23712 bait|prey|null|- prey|bait|bait|- ab CG3815 MI:0004(affinity chromatography technology) 19782028 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_63785 prey bait ab eIF5 MI:0004(affinity chromatography technology) 22271760 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (biogrid) BIOGRID_633197 prey bait ab Paf-AHalpha MI:0004(affinity chromatography technology) 21987634 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0799(additive genetic interaction defined by inequality) (biogrid) BIOGRID_617897 bait prey ab l(1)G0156 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19325107 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0799(additive genetic interaction defined by inequality)|MI:0799(additive genetic interaction defined by inequality) (biogrid)|(biogrid) BIOGRID_577701|BIOGRID_576774 prey|bait bait|prey CadN ab MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19325107 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0799(additive genetic interaction defined by inequality)|MI:0799(additive genetic interaction defined by inequality) (biogrid)|(biogrid) BIOGRID_576318|BIOGRID_577705 prey|bait bait|prey spi ab MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0399(two hybrid fragment pooling approach)|MI:0018(two hybrid) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint) DIP_27795|BIOGRID_62522|MINT_19772|MINT_19370|UniProt_42753|MINT_19571 -|bait|bait|bait|bait|bait -|prey|prey|prey|prey|prey ab so MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0465(dip)|MI:0471(mint)|(intact) BIOGRID_35862|DIP_8205|MINT_18044|UniProt_54285 prey|-|null|null bait|-|bait|bait ab ptc MI:0399(two hybrid fragment pooling approach) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) (intact) UniProt_41630 prey bait nrv2 ab MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21987634 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0799(additive genetic interaction defined by inequality)|MI:0799(additive genetic interaction defined by inequality) (biogrid)|(biogrid) BIOGRID_621575|BIOGRID_625281 prey|bait bait|prey ab drongo MI:0018(two hybrid) 14605208 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0465(dip) DIP_22266 - - Ef1alpha48D ab MI:0018(two hybrid) 10688190 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0407(direct interaction) (biogrid) BIOGRID_349229 bait prey ptc ab MI:0018(two hybrid) 15710747 taxid:7227(Drosophila melanogaster) taxid:7227(Drosophila melanogaster) MI:0915(physical association) MI:0465(dip) DIP_26638 - -

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q24174 O17468 AB HIRA 0.21 19782028 Q9VW57 Q24174 GRASP65 AB 0.21 14605208 Q24174 P18502 AB PTC 0.21 15710747 Q9VPU3 Q24174 DRONGO AB 0.21 14605208 Q24174 Q01083 AB SPI 0.309 15710747 Q8IGE8 Q24174 PTC AB 0.126 15710747 Q27350 Q24174 SO AB 0.354 14605208