PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O94451 P36592 enzymatic study 18031226 direct interaction X 2 O94451 P53692 enzymatic study 18031226 direct interaction X 2 O94451 Q09811 enzymatic study 18031226 direct interaction X 2 O94451 O94395 enzymatic study 18031226 direct interaction X 2 O94451 O42915 two hybrid 24265825 direct interaction X 2 O94451 O42915 pull down 24265825 direct interaction X 2 O94451 O59793 two hybrid 11751918 direct interaction X 2 O94451 P07799 enzymatic study 18031226 direct interaction X 2 O94451 O60126 enzymatic study 18031226 direct interaction X 2 O94451 Q9USX3 pull down 19363481 physical association X 2 O94451 O59793 two hybrid 11751918 physical association X 2 O94451 O13826 two hybrid 17762864 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality RFP1 PLI1 17762864 0018 LC UFD1 PLI1 24265825,24265825 0018,0096 LC BIS1 PLI1 11751918 0018 LC TOP3 PLI1 18031226 0415 LC PKU70 PLI1 18031226 0415 LC PLI1 TOP1 18031226 0415 LC PLI1 RAD22 18031226 0415 LC PLI1 SMC6 18031226 0415 LC PLI1 RQH1 18031226 0415 LC UFD1 PLI1 24265825,24265825 0018,0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID O94451 O59793 PLI1 BIS1 0.309 11751918 O94451 O13826 PLI1 RFP1 0.309 17762864 O94451 O60126 PLI1 TOP3 0.309 18031226 O94451 O94395 PLI1 PKU70 0.309 18031226 P07799 O94451 TOP1 PLI1 0.309 18031226 P36592 O94451 RAD22 PLI1 0.309 18031226 P53692 O94451 SMC6 PLI1 0.309 18031226 Q09811 O94451 RQH1 PLI1 0.309 18031226 Q9USX3 O94451 RAD60 PLI1 0.21 19363481 O94451 O42915 PLI1 UFD1 0.523 24265825