PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P40995 O14343 - 14573463 - X 2 P40995 O59751 - 14573463 - X 2 P40996 P40995 - 8943016 - X 2 P40995 O14343 two hybrid 14573463 direct interaction X 2 P40995 O59751 two hybrid 14573463 direct interaction X 2 P40995 O14343 affinity chromatography technology 14573463 physical association X 2 P40995 O59751 affinity chromatography technology 14573463 physical association X 2 P40995 P29366 pull down 11483497 direct interaction X 2 Q9HE04 P40995 affinity chromatography technology 14637153 physical association X 2 P40995 Q01112 two hybrid 23615447 direct interaction X 2 P40995 P08647 two hybrid 16754851 direct interaction X 2 P40995 Q01112 affinity chromatography technology 12409291 physical association X 2 P40995 two hybrid 9892665 direct interaction X 2 P40995 pull down 9892665 direct interaction X 2 P40995 affinity chromatography technology 9892665 physical association X 2 P40995 Q09914 affinity chromatography technology 14637153 physical association X 2 P40995 Q10133 affinity chromatography technology 14637153 physical association X 2 P40995 O13928 affinity chromatography technology 14637153 physical association X 2 P40995 Q874R1 affinity chromatography technology 14637153 physical association X 2 P40995 Q01112 affinity chromatography technology 14637153 physical association X 2 P40996 P40995 two hybrid 23615447 direct interaction X 2 P40996 P40995 two hybrid 9660817 direct interaction X 2 P40996 P40995 two hybrid 7923372 direct interaction X 2 P40996 P40995 affinity chromatography technology 12409291 physical association X 2 P40996 P40995 far western blotting 10567532 direct interaction X 2 P40996 P40995 two hybrid 10567532 direct interaction X 2 P40996 P40995 pull down 11483497 direct interaction X 2 P40995 P08647 two hybrid 16754851 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality KLP5 SCD1 14573463,14573463 0004,0018 LC KLP6 SCD1 14573463,14573463 0004,0018 LC O60130 SCD1 26771498 0018 HT SCD1 SCD2 9660817,10567532,23615447,7923372,10567532,8943016 0018,0018,0018,0018,0047,0018 LC SCD1 CDC42 23615447 0018 LC SCD1 UPI0000162091 9892665,9892665,9892665 0096,0018,0004 LC RHO3 SCD1 14637153 0004 LC KLP5 SCD1 14573463,14573463 0004,0018 LC KLP6 SCD1 14573463,14573463 0004,0018 LC SCD1 SCD2 12409291,11483497 0004,0096 LC SCD1 CDC42 14637153,12409291 0004,0004 LC SCD1 RHO1 14637153 0004 LC SCD1 RHO2 14637153 0004 LC SCD1 RHO4 14637153 0004 LC SCD1 RHO5 14637153 0004 LC SCD1 UPI0000162091 9892665,9892665,9892665 0096,0018,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q09914 P40995 RHO1 SCD1 0.21 14637153 Q10133 P40995 RHO2 SCD1 0.21 14637153 Q9HE04 P40995 RHO5 SCD1 0.21 14637153 Q874R1 P40995 RHO4 SCD1 0.21 14637153 P40995 O14343 SCD1 KLP5 0.454 14573463 P40995 O59751 SCD1 KLP6 0.454 14573463 P40996 P40995 SCD2 SCD1 0.914 9660817,10567532,11483497,23615447,7923372,12409291 P40995 P29366 SCD1 BEM1 0.309 11483497 P40995 O60130 SCD1 O60130 0.183 26771498 P40995 P08647 SCD1 RAS1 0.309 16754851 Q01112 P40995 CDC42 SCD1 0.569 14637153,23615447,12409291 P40995 O13928 SCD1 RHO3 0.21 14637153