PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P40996 Q01112 - 8943016 - X 2 P40996 P40995 - 8943016 - X 2 P50527 P40996 two hybrid 23615447 direct interaction X 2 P50527 P40996 two hybrid 23615447 direct interaction X 2 P50527 P40996 affinity chromatography technology 12409291 physical association X 2 P50527 P40996 enzymatic study 10567532 direct interaction X 2 P50527 P40996 far western blotting 10567532 direct interaction X 2 P50527 P40996 two hybrid 10567532 direct interaction X 2 P40996 P40996 affinity chromatography technology 12409291 physical association X 2 P40996 O74653 two hybrid 19710424 direct interaction X 2 P40996 P40995 two hybrid 23615447 direct interaction X 2 P40996 Q10447 two hybrid 23615447 direct interaction X 2 P40996 P40995 two hybrid 9660817 direct interaction X 2 P40996 Q01112 two hybrid 9660817 direct interaction X 2 P40996 Q01112 two hybrid 8943016 direct interaction X 2 P40996 P40995 two hybrid 7923372 direct interaction X 2 P40996 Q01112 two hybrid 7923372 direct interaction X 2 P40996 Q01112 affinity chromatography technology 12409291 physical association X 2 P40996 P40995 affinity chromatography technology 12409291 physical association X 2 P40996 Q01112 pull down 15631622 direct interaction X 2 P40996 P40995 far western blotting 10567532 direct interaction X 2 P40996 P40995 two hybrid 10567532 direct interaction X 2 P40996 P40995 pull down 11483497 direct interaction X 2 P40996 P11433 pull down 11483497 direct interaction X 2 P50527 P40996 two hybrid 10567532 physical association X 2 P50527 P40996 far western blotting 10567532 direct interaction X 2 P50527 P40996 protein kinase assay 10567532 phosphorylation reaction X 2 P40996 Q01112 isothermal titration calorimetry 15631622 direct interaction X 2 P40996 Q01112 isothermal titration calorimetry 15631622 direct interaction X 2 P40996 Q01112 isothermal titration calorimetry 15631622 direct interaction X 2 P40996 Q01112 surface plasmon resonance 15631622 direct interaction X 2 P40996 Q01112 affinity chromatography technology 15631622 direct interaction X 2

PPI - HINT Gene A Gene B PMID Method Quality POB1 SCD2 19710424 0018 LC SCD1 SCD2 9660817,10567532,23615447,7923372,10567532,8943016 0018,0018,0018,0018,0047,0018 LC SCD2 SHK1 10567532,10567532,23615447,10567532,10567532 0415,0018,0018,0047,0424 LC SCD2 CDC42 9660817,7923372,15631622,15631622,8943016,15631622,15631622 0018,0018,0004,0107,0018,0065,0096 LC SCD2 PPK2 23615447 0018 LC SCD1 SCD2 12409291,11483497 0004,0096 LC SCD2 SCD2 12409291 0004 LC SCD2 SHK1 12409291 0004 LC SCD2 CDC42 12409291,15631622,15631622,15631622,15631622 0004,0004,0107,0065,0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q01112 P40996 CDC42 SCD2 0.941 9660817,15631622,7923372,8943016,12409291 P40996 P40995 SCD2 SCD1 0.914 9660817,10567532,11483497,23615447,7923372,12409291 P50527 P40996 SHK1 SCD2 0.917 12409291,10567532,23615447 P40996 P11433 SCD2 CDC24 0.309 11483497 P40996 O74653 SCD2 POB1 0.309 19710424 Q10447 P40996 PPK2 SCD2 0.309 23615447 P40996 P40996 SCD2 SCD2 0.236 12409291