PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O14170 O13790 affinity chromatography technology 23535663 physical association X 2 O14170 P41411 affinity chromatography technology 10209119 physical association X 2 O14170 P41411 affinity chromatography technology 9653157 physical association X 2 O14170 P41411 affinity chromatography technology 9653157 physical association X 2 O14170 P87060 affinity chromatography technology 9990507 physical association X 2 O14170 P87060 affinity chromatography technology 9990507 physical association X 2 O14170 O13790 affinity chromatography technology 9990507 physical association X 2 O14170 P87060 affinity chromatography technology 10209119 physical association X 2 O14170 O13959 affinity chromatography technology 12167173 physical association X 2 O14170 O13959 affinity chromatography technology 12167173 physical association X 2 O14170 P87060 affinity chromatography technology 12167173 physical association X 2 O14170 P87060 affinity chromatography technology 12167173 physical association X 2 O14170 O13790 affinity chromatography technology 12167173 physical association X 2 O14170 Q9Y709 affinity chromatography technology 12167173 physical association X 2 O14170 Q9Y709 two hybrid 17016471 direct interaction X 2 O14170 O14170 affinity chromatography technology 9990507 physical association X 2 P40380 O14170 pull down 12167173 direct interaction X 2 O14170 pull down 12167173 association C 3 O14170 P87060 anti bait coimmunoprecipitation 10209119 physical association X 2 O14170 P87060 anti bait coimmunoprecipitation 10209119 physical association X 2 O14170 P87060 anti tag coimmunoprecipitation 12167173 physical association X 2 O14170 P87060 anti tag coimmunoprecipitation 12167173 physical association X 2 O14170 P87060 anti tag coimmunoprecipitation 12167173 physical association X 2 O14170 P87060 anti bait coimmunoprecipitation 12167173 physical association X 2 O14170 Q9Y709 anti bait coimmunoprecipitation 15147268 physical association X 2 O14170 Q9Y709 two hybrid 17016471 physical association X 2 O14170 P41411 anti tag coimmunoprecipitation 9653157 physical association X 2 O14170 P41411 anti tag coimmunoprecipitation 9653157 physical association X 2 O14170 P87060 pull down 9990507 physical association X 2 O14170 P87060 anti tag coimmunoprecipitation 9990507 physical association X 2 O14170 P87060 anti tag coimmunoprecipitation 9990507 physical association X 2 O14170 O13790 anti tag coimmunoprecipitation 9990507 physical association X 2 O14170 anti bait coimmunoprecipitation 10209119 association C 3 O14170 anti bait coimmunoprecipitation 12167173 association C 4 O14170 anti bait coimmunoprecipitation 12167173 association C 4 O14170 anti bait coimmunoprecipitation 12167173 association C 5 O14170 anti bait coimmunoprecipitation 12167173 association C 5 O14170 anti bait coimmunoprecipitation 12167173 association C 5 O14170 anti bait coimmunoprecipitation 12167173 association C 5 O14170 O14170 anti tag coimmunoprecipitation 9990507 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality POP2 SKP1 17016471 0018 LC CUL1 POP2 9990507,12167173,9990507,23535663,12167173 0007,0006,0004,0004,0004 LC PIP1 POP2 12167173,12167173 0006,0004 LC POP2 POP2 9990507,9990507 0007,0004 LC POP2 RUM1 12167173 0096 LC POP2 CDC18 10209119,9653157,9653157,10209119 0006,0004,0007,0004 LC POP2 POP1 9990507,9990507,12167173,9990507,10209119,10209119,12167173,12167173,12167173 0096,0007,0096,0004,0006,0004,0004,0007,0006 LC POP2 SKP1 15147268,12167173,12167173 0006,0006,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID O14170 O13959 POP2 PIP1 0.61 12167173 O14170 O14170 POP2 POP2 0.416 9990507 Q9Y709 O14170 SKP1 POP2 0.671 17016471,15147268,12167173 O14170 O13790 POP2 CUL1 0.757 23535663,12167173,9990507 P87060 O14170 POP1 POP2 0.963 12167173,9990507,10209119 P40380 O14170 RUM1 POP2 0.454 12167173 P41411 O14170 CDC18 POP2 0.692 10209119,9653157