PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9URV2 - 12477395 - C 13 Q9URV2 O42839 affinity chromatography technology 10526233 physical association X 2 Q9URV2 P10505 affinity chromatography technology 8918880 physical association X 2 Q9URV2 P41889 affinity chromatography technology 8918880 physical association X 2 Q9URV2 O42839 affinity chromatography technology 12477395 physical association X 2 Q9URV2 O42839 affinity chromatography technology 16950791 physical association X 2 Q9URV2 P41889 biochemical 10526233 colocalization X 2 Q9URV2 O42839 biochemical 10526233 colocalization X 2 Q9URV2 P10505 biochemical 10526233 colocalization X 2 Q9URV2 P41889 biochemical 8918880 colocalization X 2 Q9URV2 P10505 biochemical 8918880 colocalization X 2 Q9URV2 O42839 affinity chromatography technology 18082611 physical association X 2 Q9URV2 O42839 affinity chromatography technology 18556659 physical association X 2 Q9URV2 O59767 affinity chromatography technology 18556659 physical association X 2 O94444 Q9URV2 pull down 12615927 direct interaction X 2 Q9URV2 Q874R3 affinity chromatography technology 18354085 physical association X 2 Q9URV2 O74358 affinity chromatography technology 12477395 physical association X 2 Q9URV2 Q09823 affinity chromatography technology 19756689 physical association X 2 Q9URV2 tandem affinity purification 12477395 association C 13 Q9URV2 tandem affinity purification 12477395 association C 13 Q9URV2 cosedimentation through density gradient 15148393 physical association C 5

PPI - HINT Gene A Gene B PMID Method Quality CUT20 CUT4 10526233,10526233 0401,0004 LC O74469 CUT4 15148393 0029 LC NUC2 CUT4 10526233,8918880,8918880 0401,0401,0004 LC CDC13 CUT4 21389117 0415 LC CUT2 CUT4 21389117 0415 LC CUT3 CUT4 15148393 0029 LC MES1 CUT4 21389117 0415 LC CUT9 CUT4 10526233,8918880,8918880,15148393 0401,0401,0004,0029 LC CUT4 CND2 15148393 0029 LC CUT20 CUT4 12477395,12477395,18082611,10526233,16950791,10526233,18556659 0676,0004,0004,0401,0004,0004,0004 LC MAD3 CUT4 18556659 0004 LC APC13 CUT4 12477395,12477395 0004,0676 LC RPN10 CUT4 12615927 0096 LC NUC2 CUT4 10526233,8918880,8918880 0401,0401,0004 LC CUT9 CUT4 10526233,8918880,8918880 0401,0401,0004 LC REC10 CUT4 19756689 0004 LC APC2 CUT4 18354085 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9URV2 Q09823 CUT4 REC10 0.21 19756689 Q9URV2 O59767 CUT4 MAD3 0.21 18556659 Q9URV2 O94444 CUT4 RPN10 0.309 12615927 Q9URV2 Q874R3 CUT4 APC2 0.21 18354085 Q9URV2 O74358 CUT4 APC13 0.236 12477395 Q9URV2 P41889 CUT4 CUT9 0.396 10526233,8918880 Q9URV2 P10505 CUT4 NUC2 0.396 10526233,8918880 Q9URV2 O42839 CUT4 CUT20 0.74 18082611,18556659,12477395,16950791,10526233