PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O14170 P87060 affinity chromatography technology 9990507 physical association X 2 O14170 P87060 affinity chromatography technology 9990507 physical association X 2 O14170 P87060 affinity chromatography technology 10209119 physical association X 2 O14170 P87060 affinity chromatography technology 12167173 physical association X 2 O14170 P87060 affinity chromatography technology 12167173 physical association X 2 O13959 P87060 affinity chromatography technology 12167173 physical association X 2 O13959 P87060 affinity chromatography technology 12167173 physical association X 2 P87060 P41411 affinity chromatography technology 9203581 physical association X 2 P87060 O13790 affinity chromatography technology 23535663 physical association X 2 P87060 O13790 affinity chromatography technology 10880460 physical association X 2 P87060 O13790 affinity chromatography technology 12167173 physical association X 2 P87060 P41411 pull down 14970237 direct interaction X 2 Q9Y709 P87060 affinity chromatography technology 15147268 physical association X 2 Q9Y709 P87060 affinity chromatography technology 12167173 physical association X 2 P40380 P87060 pull down 12167173 direct interaction X 2 P40380 P87060 pull down 14970237 direct interaction X 2 P87060 P87060 affinity chromatography technology 9990507 physical association X 2 P87060 P36630 affinity chromatography technology 14970237 physical association X 2 P87060 P36630 pull down 14970237 direct interaction X 2 P87060 pull down 12167173 association C 3 O14170 P87060 anti bait coimmunoprecipitation 10209119 physical association X 2 O14170 P87060 anti bait coimmunoprecipitation 10209119 physical association X 2 O14170 P87060 anti tag coimmunoprecipitation 12167173 physical association X 2 O14170 P87060 anti tag coimmunoprecipitation 12167173 physical association X 2 O14170 P87060 anti tag coimmunoprecipitation 12167173 physical association X 2 O14170 P87060 anti bait coimmunoprecipitation 12167173 physical association X 2 O14170 P87060 pull down 9990507 physical association X 2 O14170 P87060 anti tag coimmunoprecipitation 9990507 physical association X 2 O14170 P87060 anti tag coimmunoprecipitation 9990507 physical association X 2 P87060 P41411 pull down 14970237 physical association X 2 P87060 P41411 anti tag coimmunoprecipitation 9203581 physical association X 2 P87060 anti bait coimmunoprecipitation 10209119 association C 3 P87060 anti bait coimmunoprecipitation 12167173 association C 4 P87060 anti bait coimmunoprecipitation 12167173 association C 5 P87060 anti bait coimmunoprecipitation 12167173 association C 5 P87060 anti bait coimmunoprecipitation 12167173 association C 5 P87060 anti bait coimmunoprecipitation 12167173 association C 5 Q9Y709 P87060 anti bait coimmunoprecipitation 15147268 physical association X 2 P40380 P87060 pull down 14970237 physical association X 2 P87060 P36630 pull down 14970237 physical association X 2 P87060 P36630 anti tag coimmunoprecipitation 14970237 physical association X 2 P87060 P36630 pull down 14970237 physical association X 2 P87060 P36630 pull down 14970237 physical association X 2 P87060 P87060 anti tag coimmunoprecipitation 9990507 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality POP1 WOS2 26771498 0018 HT CUL1 POP1 12167173,23535663,10880460,12167173 0006,0004,0004,0004 LC PIP1 POP1 12167173,12167173 0006,0004 LC POP2 POP1 9990507,9990507,12167173,9990507,10209119,10209119,12167173,12167173,12167173 0096,0007,0096,0004,0006,0004,0004,0007,0006 LC CBF11 POP1 22540037 0004 LC CIG2 POP1 14970237,14970237,14970237 0004,0096,0007 LC RUM1 POP1 12167173,14970237 0096,0096 LC CDC18 POP1 10209119,9203581,9203581,14970237 0006,0004,0007,0096 LC POP1 POP1 9990507,9990507 0007,0004 LC POP1 SKP1 15147268,12167173,12167173,15147268 0006,0006,0004,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q11118 P87060 WOS2 POP1 0.183 26771498 Q9Y709 P87060 SKP1 POP1 0.61 12167173,15147268 P87060 P87060 POP1 POP1 0.416 9990507 P87060 P41411 POP1 CDC18 0.731 9203581,10209119,14970237 P87060 P36630 POP1 CIG2 0.659 14970237 P87060 O13959 POP1 PIP1 0.61 12167173 P87060 O14170 POP1 POP2 0.963 12167173,9990507,10209119 P87060 P40380 POP1 RUM1 0.623 14970237,12167173 P87060 O13790 POP1 CUL1 0.61 10880460,23535663,12167173