PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9USX3 Q09170 pull down 16880212 direct interaction X 2 Q9USX3 Q09170 affinity chromatography technology 16880212 physical association X 2 Q9USX3 Q09170 affinity chromatography technology 16880212 physical association X 2 Q9USX3 Q09170 enzymatic study 16880212 direct interaction X 2 Q9USX3 Q09170 two hybrid 12897162 direct interaction X 2 Q9USX3 Q09170 affinity chromatography technology 12897162 physical association X 2 Q9USX3 P87176 pull down 17762865 direct interaction X 2 Q9USX3 P87176 enzymatic study 17762865 direct interaction X 2 Q9USX3 Q09170 enzymatic study 19755492 direct interaction X 2 Q9USX3 Q9USX3 affinity chromatography technology 16880212 physical association X 2 Q9USX3 O13710 affinity chromatography technology 12897162 physical association X 2 O94451 Q9USX3 pull down 19363481 physical association X 2 Q9USX3 P40984 pull down 19363481 direct interaction X 2 Q9USX3 P40984 pull down 19363481 direct interaction X 2 Q9USX3 O42939 pull down 19363481 physical association X 2 Q9USX3 Q09170 pull down 12897162 physical association X 2 Q9USX3 P87176 pull down 17762865 physical association X 2 Q9USX3 O13710 pull down 12897162 physical association X 2 Q9USX3 P53692 pull down 12897162 physical association X 2 Q9USX3 O13710 tandem affinity purification 12897162 association X 2 Q9USX3 O13826 two hybrid 17762864 physical association X 2 Q9USX3 O13826 two hybrid 17762865 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality RFP1 RAD60 17762865,17762864 0018,0018 LC SLX8 RAD60 17762865,17762865 0415,0096 LC CDS1 RAD60 12897162,19755492,12897162,16880212,12897162,16880212,16880212 0018,0415,0004,0004,0096,0415,0096 LC SMC5 RAD60 12897162,12897162,12897162 0004,0676,0096 LC SMC6 RAD60 12897162 0096 LC SLX8 RAD60 17762865,17762865 0415,0096 LC CDS1 RAD60 12897162,12897162,16880212,12897162,16880212,16880212 0018,0004,0004,0096,0415,0096 LC RAD60 RAD60 16880212 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9USX3 O94451 RAD60 PLI1 0.21 19363481 Q9USX3 O42939 RAD60 UBA2 0.21 19363481 Q9USX3 P40984 RAD60 HUS5 0.722 19363481,21444718 Q9USX3 Q09170 RAD60 CDS1 0.858 19755492,16880212,12897162 Q9USX3 O13710 RAD60 SMC5 0.21 12897162 Q9USX3 O13826 RAD60 RFP1 0.523 17762864,17762865 Q9USX3 Q9USX3 RAD60 RAD60 0.236 16880212 Q9USX3 P87176 RAD60 SLX8 0.623 17762865