PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q874R3 P41889 affinity chromatography technology 18354085 physical association X 2 O59767 Q874R3 affinity chromatography technology 18556659 physical association X 2 O74358 Q874R3 affinity chromatography technology 12477395 physical association X 2 Q9URV2 Q874R3 affinity chromatography technology 18354085 physical association X 2 O42839 Q874R3 affinity chromatography technology 12477395 physical association X 2 O42839 Q874R3 affinity chromatography technology 16950791 physical association X 2 O42839 Q874R3 affinity chromatography technology 18082611 physical association X 2 O42839 Q874R3 affinity chromatography technology 18556659 physical association X 2 P10505 Q874R3 affinity chromatography technology 18354085 physical association X 2 Q9UT86 Q874R3 two hybrid 16950791 direct interaction X 2 Q874R3 tandem affinity purification 12477395 association C 13 Q874R3 tandem affinity purification 12477395 association C 13

PPI - HINT Gene A Gene B PMID Method Quality CDC13 APC2 21389117 0415 LC CUT2 APC2 21389117 0415 LC MES1 APC2 21389117 0415 LC APC2 APC11 26771498,16950791 0018,0018 HT,LC CUT20 APC2 12477395,18082611,18556659,16950791,12477395 0004,0004,0004,0004,0676 LC MAD3 APC2 18556659 0004 LC APC13 APC2 12477395,12477395 0004,0676 LC NUC2 APC2 18354085 0004 LC CUT9 APC2 18354085 0004 LC APC2 CUT4 18354085 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q874R3 O59767 APC2 MAD3 0.21 18556659 Q874R3 P10505 APC2 NUC2 0.21 18354085 Q874R3 P41889 APC2 CUT9 0.21 18354085 Q9URV2 Q874R3 CUT4 APC2 0.21 18354085 Q874R3 O74358 APC2 APC13 0.236 12477395 Q874R3 O42839 APC2 CUT20 0.623 18082611,18556659,12477395,16950791 Q9UT86 Q874R3 APC11 APC2 0.436 16950791,26771498