PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O94244 - 15369671 - X 2 O94244 - 15369671 - X 2 O42995 O94244 affinity chromatography technology 24789708 physical association X 2 O42995 O94244 affinity chromatography technology 24789708 physical association X 2 O42995 O94244 affinity chromatography technology 24789708 physical association X 2 O42995 O94244 affinity chromatography technology 24789708 physical association X 2 O42995 O94244 affinity chromatography technology 24774534 physical association X 2 O42995 O94244 two hybrid 24774534 direct interaction X 2 O42995 O94244 two hybrid 24774534 direct interaction X 2 O94244 O94682 affinity chromatography technology 24774534 physical association X 2 O94244 O94682 affinity chromatography technology 24774534 physical association X 2 Q9P802 O94244 affinity chromatography technology 15369671 physical association X 2 Q9P802 O94244 affinity chromatography technology 24789708 physical association X 2 Q9P802 O94244 affinity chromatography technology 24789708 physical association X 2 Q9P802 O94244 affinity chromatography technology 24774534 physical association X 2 Q9P802 O94244 affinity chromatography technology 24774534 physical association X 2 Q9P802 O94244 affinity chromatography technology 15369671 physical association X 2 O94244 O59793 two hybrid 11751918 direct interaction X 2 Q9UTM7 O94244 affinity chromatography technology 22771823 physical association X 2 Q9UTM7 O94244 affinity chromatography technology 24789708 physical association X 2 Q9UTM7 O94244 affinity chromatography technology 24789708 physical association X 2 Q9UTM7 O94244 affinity chromatography technology 24789708 physical association X 2 Q9UTM7 O94244 affinity chromatography technology 24774534 physical association X 2 Q9UTM7 O94244 affinity chromatography technology 24774534 physical association X 2 Q9UTM7 O94244 two hybrid 24774534 direct interaction X 2 Q9UTM7 O94244 two hybrid 24774534 direct interaction X 2 Q9P802 O94244 anti tag coimmunoprecipitation 15369671 physical association X 2 Q9P802 O94244 anti tag coimmunoprecipitation 15369671 physical association X 2 O94244 O59793 two hybrid 11751918 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality O42995 MIS16 24774534,24774534 0018,0004 LC BIS1 MIS16 11751918 0018 LC MIS16 MIS18 15369671,15369671,15369671 0019,0004,0007 LC MIS16 HAT1 24774534,24774534 0004,0018 LC O42995 MIS16 24789708,24774534,24774534 0004,0018,0004 LC MIS16 O94682 24774534 0004 LC MIS16 HHF1|HHF2|HHF3 26343758 0096 LC MIS16 Q9HDY7 26343758 0096 LC MIS16 MIS18 24789708,15369671,15369671,15369671,24774534 0004,0019,0004,0007,0004 LC MIS16 HAT1 24789708,24774534,24774534,22771823 0004,0004,0018,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID O94244 O59793 MIS16 BIS1 0.309 11751918 O94682 O94244 O94682 MIS16 0.376 24774534 P09322 O94244 HHF3 MIS16 0.309 26343758 Q9HDY7 O94244 Q9HDY7 MIS16 0.309 26343758 O94244 O42995 MIS16 O42995 0.765 24789708,24774534 Q9P802 O94244 MIS18 MIS16 0.757 15369671,24789708,24774534 Q9UTM7 O94244 HAT1 MIS16 0.853 24789708,22771823,24774534