PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P50527 Q9US59 two hybrid 23615447 direct interaction X 2 P50527 Q9US59 two hybrid 10593886 direct interaction X 2 P50527 Q9US59 affinity chromatography technology 10593886 physical association X 2 Q9US59 P40371 two hybrid 23695164 direct interaction X 2 Q9US59 P40371 two hybrid 23615447 direct interaction X 2 Q10407 Q9US59 affinity chromatography technology 22570491 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality PTC1 SKB5 23695164,26771498,23615447 0018,0018,0018 HT,LC SHK1 SKB5 10593886,23615447,10593886 0004,0018,0018 LC SKB5 SKB5 26771498 0018 HT SHK1 SKB5 10593886,10593886 0004,0018 LC MKH1 SKB5 22570491 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9US59 P50527 SKB5 SHK1 0.623 23615447,10593886 Q9US59 Q10407 SKB5 MKH1 0.21 22570491 Q9US59 Q9US59 SKB5 SKB5 0.21 26771498 Q9US59 P40371 SKB5 PTC1 0.539 23695164,23615447,26771498