PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus gpd-3 apc-2 14704431 biogrid,i2d exp G apc-2 unc-87 14704431 biogrid,i2d,mint,intact exp G apc-2 rpl-3 14704431 biogrid,i2d,mint,intact exp G apc-2 C39D10.7 14704431 biogrid,i2d,mint,intact exp gpd-2 apc-2 14704431 i2d,mint,intact exp G apc-2 F35G12.9 18692475,unassigned701,19123269,14704431 biogrid,i2d,mint,intact exp G rpl-21 apc-2 14704431 biogrid,i2d,mint,intact exp G apc-2 pal-1 14704431 biogrid,i2d,mint,intact exp apc-2 Uncharacterized protein C30C11.4 14704431 biogrid,i2d,mint,intact exp G apc-2 cks-1 14704431 biogrid,i2d,mint,intact exp G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P34514 Q05036 two hybrid 14704431 direct interaction X 2 P34514 P34766-2 two hybrid 14704431 direct interaction X 2 P34514 two hybrid 14704431 direct interaction X 2 P34514 P37806-3 two hybrid 14704431 direct interaction X 2 P34514 P50880 two hybrid 14704431 direct interaction X 2 P34514 P17330 two hybrid 14704431 direct interaction X 2 P34514 Q95XM4 two hybrid 14704431 direct interaction X 2 P34334 P34514 two hybrid 14704431 direct interaction X 2 Q20052 P34514 two hybrid 18692475 direct interaction X 2 Q20052 P34514 two hybrid 14704431 direct interaction X 2 P34514 Q05036 two hybrid pooling approach 14704431 physical association X 2 P34514 Q18529 two hybrid pooling approach 14704431 physical association X 2 P34514 P50880 two hybrid pooling approach 14704431 physical association X 2 P34514 P17329 two hybrid pooling approach 14704431 physical association X 2 P34514 P34766 two hybrid pooling approach 14704431 physical association X 2 P34514 P37806 two hybrid pooling approach 14704431 physical association X 2 P34514 Q95XM4 two hybrid pooling approach 14704431 physical association X 2 P34334 P34514 two hybrid pooling approach 14704431 physical association X 2 Q20052 P34514 two hybrid pooling approach 14704431 physical association X 2 Q20052 P34514 two hybrid pooling approach 14704431 physical association X 2 Q20052 P34514 two hybrid pooling approach 19123269 physical association X 2 Q20052 P34514 two hybrid pooling approach 19123269 physical association X 2 Q20052 P34514 two hybrid array 19123269 physical association X 2 Q20052 P34514 two hybrid array 19123269 physical association X 2 Q20052 P34514 two hybrid - physical association X 2 Q20052 P34514 two hybrid - physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B gpd-2 apc-2 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(intact) DIP_2763|MINT_1182|UniProt_31148 -|prey|prey -|bait|bait gpd-3 apc-2 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction) (biogrid) BIOGRID_23221 prey bait apc-2 rpl-3 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|MI:0465(dip)|(intact) BIOGRID_23220|MINT_1180|DIP_2762|UniProt_31147 bait|bait|-|bait prey|prey|-|prey apc-2 pal-1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(biogrid)|MI:0471(mint)|(intact) DIP_2759|BIOGRID_23217|MINT_1177|UniProt_31141 -|bait|bait|bait -|prey|prey|prey apc-2 apc-11 MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14704431,18692475,19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0465(dip)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(biogrid) UniProt_20789|UniProt_30611|UniProt_24802|MINT_4730|MINT_4731|DIP_2229|MINT_1181|UniProt_25179|MINT_535|MINT_4729|UniProt_18874|UniProt_31146|UniProt_18877|UniProt_20790|BIOGRID_29122|BIOGRID_22589 prey|prey|prey|prey|prey|-|bait|prey|prey|prey|bait|bait|prey|bait|prey|prey bait|bait|bait|bait|bait|-|prey|bait|bait|bait|prey|prey|bait|prey|bait|bait apc-2 unc-87 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(biogrid)|(intact)|MI:0471(mint) DIP_2761|BIOGRID_23219|UniProt_31145|MINT_1179 -|bait|bait|bait -|prey|prey|prey apc-2 Y71G12B.27 MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0465(dip)|MI:0471(mint) UniProt_29117|DIP_4725|MINT_3281 prey|-|prey bait|-|bait apc-2 C39D10.7 MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(intact)|MI:0471(mint) DIP_2760|UniProt_31142|MINT_1178 -|bait|bait -|prey|prey apc-2 C30C11.4 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(biogrid)|MI:0471(mint)|(intact) DIP_2758|BIOGRID_23216|MINT_1176|UniProt_31143 -|bait|bait|bait -|prey|prey|prey rpl-21 apc-2 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(biogrid)|(intact) DIP_2757|MINT_1175|BIOGRID_23215|UniProt_31144 -|prey|prey|prey -|bait|bait|bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P34514 P17329 APC-2 GPD-2 0.155 14704431 Q20052 P34514 APC-11 APC-2 0.808 14704431,unassigned701,18692475,19123269 P37806 P34514 UNC-87 APC-2 0.286 14704431 Q95XM4 P34514 Q95XM4 APC-2 0.155 14704431 P34514 P34334 APC-2 RPL-21 0.309 14704431 P34514 P17330 APC-2 GPD-3 0.183 14704431 P34766 P34514 PAL-1 APC-2 0.286 14704431 Q05036 P34514 Q05036 APC-2 0.309 14704431 Q18529 P34514 Q18529 APC-2 0.155 14704431 P50880 P34514 RPL-3 APC-2 0.309 14704431