PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus bag-1 nhr-2 14704431 biogrid,i2d,mint,intact exp bag-1 Y94H6A.9a 14704431 biogrid,i2d,mint,intact,dip exp G bag-1 hsp-1 14704431 biogrid,i2d,mint,intact,dip exp G bag-1 T03G11.6 14704431 biogrid,i2d,mint,intact,dip exp bag-1 Y43F8B.2a 19123269,14704431 biogrid,i2d,mint,intact,dip exp G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P09446 O44739 - 14704431 - X 2 Q9XWX7 O44739 - 14704431 - X 2 O44739 - 14704431 - X 2 Q10902 O44739 - 14704431 - X 2 Q9N2W5 O44739 - 14704431 - X 2 P09446 O44739 two hybrid 14704431 direct interaction X 2 O44739 two hybrid 14704431 direct interaction X 2 Q10902 O44739 two hybrid 14704431 direct interaction X 2 Q86DD7 O44739 two hybrid 14704431 direct interaction X 2 O44739 D9PTP0 two hybrid 14704431 direct interaction X 2 P09446 O44739 two hybrid 14704431 physical association X 2 Q9XWX7 O44739 two hybrid 14704431 physical association X 2 O44739 two hybrid 14704431 physical association X 2 Q9N2W5 O44739 two hybrid 14704431 physical association X 2 P09446 O44739 two hybrid pooling approach 14704431 physical association X 2 Q9XWX7 O44739 two hybrid pooling approach 14704431 physical association X 2 Q9XWX7 O44739 two hybrid pooling approach 19123269 physical association X 2 Q9XWX7 O44739 two hybrid array 19123269 physical association X 2 Q10902 O44739 two hybrid pooling approach 14704431 physical association X 2 Q9N2W5 O44739 two hybrid pooling approach 14704431 physical association X 2 Q22123 O44739 two hybrid pooling approach 14704431 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B bag-1 ubxn-2 MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(intact)|MI:0471(mint) DIP_2588|UniProt_30974|MINT_994 -|bait|bait -|prey|prey bag-1 nhr-2 MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|MI:0471(mint) UniProt_30970|BIOGRID_23030|MINT_990 bait|bait|bait prey|prey|prey bag-1 Y43F8B.2 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach) 14704431,19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|MI:0465(dip)|(intact)|MI:0471(mint) UniProt_19142|UniProt_21052|DIP_2587|UniProt_30973|MINT_993 bait|bait|-|bait|bait prey|prey|-|prey|prey bag-1 hsp-1 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0471(mint)|(biogrid)|MI:0465(dip) UniProt_30971|MINT_991|BIOGRID_23031|DIP_2585 bait|bait|bait|- prey|prey|prey|- bag-1 uniprotkb:(gene name) MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:180278() MI:0407(direct interaction) (biogrid) BIOGRID_23033 bait prey bag-1 T03G11.6 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0471(mint)|(biogrid)|MI:0465(dip) UniProt_30972|MINT_992|BIOGRID_23032|DIP_2586 bait|bait|bait|- prey|prey|prey|- bag-1 psaB MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:177057() MI:0407(direct interaction) (biogrid) BIOGRID_23034 bait prey