PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus cul-4 ddb-1 17145765 intact exp G F17E9.5 cul-4 19123269 intact exp

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q17392 Q21554 two hybrid 17145765 physical association X 2 Q17392 O61521 two hybrid pooling approach 19123269 physical association X 2 Q17392 O61521 two hybrid array 19123269 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B cul-4 ddb-1 MI:0096(pull down) 17145765 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_239 bait prey F17E9.5 cul-4 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_18721|UniProt_20634 prey|prey bait|bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q17392 O61521 CUL-4 O61521 0.236 19123269 Q21554 Q17392 DDB-1 CUL-4 0.309 17145765