PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus 3L686 T25C8.2 14704431 biogrid exp G 3L686 W02G9.3 14704431 biogrid exp 3L686 F33G12.4 20978077 biogrid exp 3L686 lmn-1 18692475,unassigned701 biogrid,intact exp G 3L686 W04D2.1a 18692475,unassigned701 biogrid,intact exp G 3L686 Y82E9BR.15 18692475,unassigned701,14704431 biogrid,intact exp 3L686 Y6B3A.1a 18692475 biogrid exp G 3L686 Y42H9AR.1 14704431 biogrid,intact exp G 3L686 cul-2 17609115 intact exp G 3L686 spk-1 18692475,unassigned701 biogrid,intact exp G 3L686 kel-8 14704431 intact exp G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants G5ECR7 - 14704431 - X 2 G5ECR7 Q9N3Y1 - 14704431 - X 2 Q9BKS1 G5ECR7 - 14704431 - X 2 Q21443 G5ECR7 two hybrid 18692475 direct interaction X 2 G5ECR7 two hybrid 14704431 direct interaction X 2 G5ECR7 Q9XVU8 two hybrid 18692475 direct interaction X 2 G5ECR7 Q9N3Y1 two hybrid 14704431 direct interaction X 2 Q03563-3 G5ECR7 two hybrid 18692475 direct interaction X 2 Q9BKS1 G5ECR7 two hybrid 18692475 direct interaction X 2 Q9BKS1 G5ECR7 two hybrid 18692475 direct interaction X 2 Q9BKS1 G5ECR7 two hybrid 14704431 direct interaction X 2 G5ECR7 O45815 two hybrid 14704431 direct interaction X 2 G5ECR7 Q19988 affinity chromatography technology 20978077 physical association X 2 Q7K783 G5ECR7 two hybrid 18692475 direct interaction X 2 G5ECR7 Q9N3Y1 two hybrid 14704431 physical association X 2 G5ED84 G5ECR7 two hybrid 14704431 physical association X 2 Q9BKS1 G5ECR7 two hybrid 14704431 physical association X 2 G5ECR7 anti tag coimmunoprecipitation 17609115 physical association C 9 Q21443 G5ECR7 two hybrid - physical association X 2 G5ECR7 Q9N3Y1 two hybrid pooling approach 14704431 physical association X 2 G5ECR7 Q9XVU8 two hybrid - physical association X 2 G5ED84 G5ECR7 two hybrid pooling approach 14704431 physical association X 2 Q03563 G5ECR7 two hybrid - physical association X 2 Q9BKS1 G5ECR7 two hybrid pooling approach 14704431 physical association X 2 Q9BKS1 G5ECR7 two hybrid - physical association X 2 Q9BKS1 G5ECR7 two hybrid - physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Y42H9AR.1 elb-1 MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_28825 prey bait spk-1 elb-1 MI:0018(two hybrid) pubmed:unassigned701 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_25208 prey bait elb-1 G5EE95 MI:0018(two hybrid) pubmed:unassigned701 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association) (intact) UniProt_25043 bait prey elb-1 kel-8 MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_28822 bait prey elc-1 elb-1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_24949|UniProt_24716|UniProt_28824 prey|bait|prey bait|prey|bait lmn-1 elb-1 MI:0018(two hybrid) pubmed:unassigned701 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24886 prey bait atn-1 elb-1 MI:0018(two hybrid) pubmed:unassigned701 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24981 prey bait