PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus fem-1 fem-3 17609115,18502413 biogrid,intact exp fem-1 par-6 18502413 biogrid exp G fem-1 tra-1 17609115 biogrid,intact exp G fem-1 Y82E9BR.15 17609115 biogrid,intact exp fem-1 fem-2 17609115,18502413 biogrid,intact exp fem-1 sel-10 15306688 intact exp G fem-1 cul-2 17609115 biogrid,intact exp, ortho G fem-1 R106.2 ortho fem-1 csn-5 ortho G Nephrocystin-4-like protein, R13H4.1 fem-1 ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P49594 P17221 affinity chromatography technology 18502413 physical association X 2 P49594 P17221 affinity chromatography technology 17609115 physical association X 2 P49594 P17221 affinity chromatography technology 17609115 physical association X 2 P34691 P17221 affinity chromatography technology 18502413 physical association X 2 P34691 P17221 affinity chromatography technology 17609115 physical association X 2 P34691 P17221 affinity chromatography technology 17609115 physical association X 2 P17221 Q17390-2 affinity chromatography technology 17609115 physical association X 2 Q9NAN2-2 P17221 affinity chromatography technology 18502413 physical association X 2 Q13617 P17221 affinity chromatography technology 17609115 physical association X 2 P17221 P34708-2 affinity chromatography technology 17609115 physical association X 2 P17221 P34708-2 enzymatic study 17609115 direct interaction X 2 Q9BKS1 P17221 affinity chromatography technology 17609115 physical association X 2 Q9BKS1 P17221 affinity chromatography technology 17609115 physical association X 2 P17221 anti tag coimmunoprecipitation 17609115 physical association C 9 P17221 anti tag coimmunoprecipitation 17609115 physical association C 3 P17221 anti tag coimmunoprecipitation 17609115 physical association C 3 P17221 anti tag coimmunoprecipitation 17609115 physical association C 3 P49594 P17221 pull down 17609115 physical association X 2 P34691 P17221 pull down 17609115 physical association X 2 Q13617 P17221 anti tag coimmunoprecipitation 17609115 physical association X 2 P34708 P17221 anti tag coimmunoprecipitation 17609115 physical association X 2 P34708 P17221 pull down 17609115 physical association X 2 P17221 anti tag coimmunoprecipitation 17609115 physical association C 6 Q93794 P17221 anti tag coimmunoprecipitation 15306688 physical association X 2 Q93794 P17221 anti tag coimmunoprecipitation 15306688 physical association X 2 Q9BKS1 P17221 anti tag coimmunoprecipitation 17609115 physical association X 2 Q9BKS1 P17221 pull down 17609115 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B fem-1 tra-1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 17609115 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_92667|UniProt_161|UniProt_174 bait|bait|prey null|null|null fem-1 fem-3 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 17609115 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_92673|UniProt_92672|UniProt_165|UniProt_166|UniProt_92671|UniProt_167|UniProt_173 prey|prey|bait|prey|bait|prey|prey bait|prey|prey|prey|prey|bait|bait fem-1 elc-1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 17609115 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact) UniProt_92666|UniProt_160|UniProt_169|UniProt_92674|UniProt_168 bait|bait|prey|prey|prey prey|prey|bait|bait|bait fem-1 sel-10 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 15306688 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_974|UniProt_973 bait|prey prey|bait fem-1 fem-2 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 17609115 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_92673|UniProt_92672|UniProt_165|UniProt_92671|UniProt_166|UniProt_167|UniProt_170 prey|prey|bait|bait|prey|prey|prey prey|bait|prey|prey|bait|prey|bait