PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus gei-17 unc-62 23791784 intact exp G F02E8.4 gei-17 19123269 intact exp T23F11.4 gei-17 23791784 intact exp G mei-2 gei-17 14704431 biogrid,i2d,mint,intact,dip exp gei-17 ubc-9 19123269 intact exp G C26E6.2 gei-17 23791784 intact exp Nuclear receptor protein, Y45G5AM.1a gei-17 23791784 intact exp G smo-1 gei-17 18692475,unassigned701,19123269 biogrid,intact exp G F13G3.1 gei-17 23791784 intact exp R02F2.5 gei-17 19123269 intact exp gei-17 cdk-9 18692475 mint exp G gei-17 gei-17 23791784 intact exp G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O44740 Q94361 two hybrid 14704431 direct interaction X 2 P55853 Q94361 two hybrid 18692475 direct interaction X 2 O44740 Q94361 two hybrid 14704431 physical association X 2 O44740 Q94361 two hybrid pooling approach 14704431 physical association X 2 P55853 Q94361 two hybrid pooling approach 19123269 physical association X 2 P55853 Q94361 two hybrid array 19123269 physical association X 2 G5EEM0 Q94361 two hybrid 23791784 physical association X 2 Q94361 Q22696 two hybrid 23791784 physical association X 2 Q18225 Q94361 two hybrid 23791784 physical association X 2 Q9N5D6 Q94361 two hybrid 23791784 physical association X 2 Q19418 Q94361 two hybrid 23791784 physical association X 2 Q21648 Q94361 two hybrid pooling approach 19123269 physical association X 2 Q21648 Q94361 two hybrid array 19123269 physical association X 2 Q19122 Q94361 two hybrid pooling approach 19123269 physical association X 2 Q19122 Q94361 two hybrid array 19123269 physical association X 2 Q95017 Q94361 two hybrid pooling approach 19123269 physical association X 2 Q95017 Q94361 two hybrid array 19123269 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B T23F11.4 gei-17 MI:0018(two hybrid) 23791784 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_33153 bait prey ztf-2 gei-17 MI:0018(two hybrid) 23791784 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_33457 prey bait CELE_F02E8.4 gei-17 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_18607|UniProt_20523 prey|prey bait|bait mei-2 gei-17 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|MI:0465(dip)|(intact) BIOGRID_23037|MINT_997|DIP_2591|UniProt_30976 bait|bait|-|bait prey|prey|-|prey smo-1 gei-17 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 18692475,19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact)|(intact)|(intact)|(intact) BIOGRID_29272|UniProt_24906|UniProt_21189|UniProt_24733|UniProt_24739|UniProt_19279 bait|bait|prey|bait|bait|prey prey|null|bait|null|null|bait gei-17 nhr-114 MI:0018(two hybrid) 23791784 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_33455 bait prey gei-17 cdk-9 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 18692475 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint) MINT_5099|MINT_5100|MINT_5101|MINT_5102|MINT_5103|MINT_5104|MINT_5098 -|-|-|-|-|-|- -|-|-|-|-|-|- gei-17 unc-62 MI:0018(two hybrid) 23791784 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_33458 bait prey flh-2 gei-17 MI:0018(two hybrid) 23791784 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_33456 prey bait gei-17 ubc-9 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_18818|UniProt_20732 bait|bait prey|prey R02F2.5 gei-17 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_19338|UniProt_21250 prey|prey bait|bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q94361 Q19418 GEI-17 ZTF-2 0.183 23791784 Q9N5D6 Q94361 UNC-62 GEI-17 0.183 23791784 Q94361 Q21648 GEI-17 Q21648 0.236 19123269 Q95017 Q94361 UBC-9 GEI-17 0.236 19123269 Q94361 Q19122 GEI-17 Q19122 0.236 19123269 Q94361 G5EEM0 GEI-17 NHR-114 0.183 23791784 Q94361 O44740 GEI-17 MEI-2 0.286 14704431 Q94361 P55853 GEI-17 SMO-1 0.583 19123269,unassigned701,18692475 Q94361 Q18225 GEI-17 FLH-2 0.183 23791784 Q9TVL3 Q94361 CDK-9 GEI-17 0.183 18692475 Q94361 Q22696 GEI-17 Q22696 0.183 23791784