PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus cmd-1 F29D10.4 i2d exp G Y53C12B.3b F29D10.4 23549480 intact exp G C04A11.4 F29D10.4 23549480 intact exp G T20F5.6 F29D10.4 23549480 intact exp G F29D10.4 F40F12.5a 23549480 intact exp G F29D10.4 Y44E3A.4 23549480 intact exp G F09F7.5a F29D10.4 23549480 intact exp Uncharacterized protein C09G1.4 F29D10.4 23549480 intact exp G UPF0183 protein T01G9.2 F29D10.4 14704431 biogrid,i2d,mint,intact exp G F29D10.4 T20H4.3a 14704431 biogrid,i2d,mint,intact,dip exp G lrs-2 F29D10.4 14704431 biogrid,mint,intact,dip exp G F29D10.4 F43B10.2a 23549480 intact exp pyp-1 F29D10.4 ortho G F29D10.4 F29D10.4 ortho G dyn-1 F29D10.4 ortho G F36D4.3b, Hum-2 F29D10.4 ortho G F25G6.6 F29D10.4 ortho G cul-1 F29D10.4 ortho G arx-6 F29D10.4 ortho Proline synthase co-transcribed bacterial homolog protein F29D10.4 ortho G C17G10.1 F29D10.4 ortho G F29D10.4 C55F2.1b ortho G F29D10.4 T26C5.3a ortho F29D10.4 Tubulin-specific chaperone B ortho G Probable protein disulfide-isomerase A4 F29D10.4 ortho G F29D10.4 gsp-1 ortho G F29D10.4 enol-1 ortho cand-1 F29D10.4 ortho G F29D10.4 lis-1 ortho G F29D10.4 C11D2.7 ortho G F29D10.4 fln-1 ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q19901 - 14704431 - X 2 Q19901 Q22620 - 14704431 - X 2 Q19901 P34692 - 14704431 - X 2 Q19901 G5EBH2 two hybrid 14704431 direct interaction X 2 Q19901 P34692-2 two hybrid 14704431 direct interaction X 2 Q19901 Q65ZK5 two hybrid 14704431 direct interaction X 2 Q19901 Q23511 two hybrid 14704431 physical association X 2 Q19901 P34692 two hybrid 14704431 physical association X 2 Q19901 Q22620 two hybrid 14704431 physical association X 2 Q19901 Q23511 two hybrid pooling approach 14704431 physical association X 2 Q19901 Q17865 two hybrid 23549480 physical association X 2 Q19901 Q7JMS4 two hybrid 23549480 physical association X 2 Q19901 P91482 two hybrid 23549480 physical association X 2 Q19901 O18218 two hybrid 23549480 physical association X 2 Q19901 Q22620 two hybrid pooling approach 14704431 physical association X 2 Q19901 P34692 two hybrid pooling approach 14704431 physical association X 2 Q19901 Q19275 two hybrid 23549480 physical association X 2 Q19901 G5EDW5 two hybrid 23549480 physical association X 2 Q19901 Q19275 two hybrid 23549480 physical association X 2 Q19901 Q6A573 two hybrid 23549480 physical association X 2 Q1XFY2 Q19901 two hybrid 23549480 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B C09G1.4 hum-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24141 prey bait T01G9.2 hum-1 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0471(mint)|MI:0465(dip)|(biogrid) UniProt_27655|MINT_1734|DIP_3268|BIOGRID_23755 bait|bait|-|bait prey|prey|-|prey hum-1 tag-343 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24145 bait prey nos-3 hum-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23590 prey bait hum-1 pars-1 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(intact) DIP_3735|MINT_2220|UniProt_28123 -|prey|prey -|bait|bait hum-1 lars-2 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(intact) DIP_4898|MINT_3487|UniProt_29292 -|prey|prey -|bait|bait hum-1 adm-2 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23587 bait prey hum-1 cyld-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24143 bait prey F09F7.5 hum-1 MI:0018(two hybrid)|MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_24142|UniProt_23586 prey|prey bait|bait hum-1 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23591 bait prey hum-1 lars-2 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction) (biogrid) BIOGRID_25450 prey bait T20F5.6 hum-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23588 prey bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q19901 Q19275 HUM-1 Q19275 0.183 23549480 Q7JMS4 Q19901 CYLD-1 HUM-1 0.183 23549480 Q6A573 Q19901 Q6A573 HUM-1 0.183 23549480 Q19901 P91482 HUM-1 P91482 0.183 23549480 Q1XFY2 Q19901 TAG-343 HUM-1 0.183 23549480 Q19901 O18218 HUM-1 NOS-3 0.183 23549480 Q19901 P34692 HUM-1 P34692 0.155 14704431 Q19901 G5EDW5 HUM-1 ADM-2 0.183 23549480 Q22620 Q19901 PARS-1 HUM-1 0.155 14704431 Q19901 Q17865 HUM-1 Q17865 0.183 23549480 Q23511 Q19901 LARS-2 HUM-1 0.155 14704431